Article
Fisheries
Man-Jun Liu, Shan Liu, Hai-Peng Liu
Summary: Hematopoiesis in crustaceans involves the continuous formation of HSCs and diverse blood cells, essential for cellular and humoral immunity. The regulation of hematopoiesis involves changes in expression of factors, while some factors play a role in maintaining cellular homeostasis. This review provides insight into the molecular regulation of crustacean hematopoiesis, contributing to a comprehensive understanding of the process.
FISH AND SHELLFISH IMMUNOLOGY REPORTS
(2021)
Article
Food Science & Technology
Xiaogang Zhang, Parinya Noisa, Jirawat Yongsawatdigul
Summary: Nine novel peptides were isolated from tilapia hydrolysate, with LPGYF and SC showing the best ABTS.+ scavenging capacity. Peptides containing C and Y were more effective than ascorbic acid, while K-containing peptides exhibited lower antioxidant activity. These peptides demonstrated potent intracellular reactive oxygen species scavenging capabilities, and were able to upregulate the expression of antioxidant enzymes in cells, with PGY being identified as the most effective cellular antioxidant.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Review
Chemistry, Multidisciplinary
Chenyang Zhang, Xin Wang, Jiangfeng Du, Zhanjun Gu, Yuliang Zhao
Summary: ROS play a vital role in physiological and pathological processes, and research on regulating ROS for disease treatments has gained wide attention. Advances in nanotechnology have led to the development of numerous nanomaterials with the ability to regulate ROS, aiming to find new and effective ROS-related nanotherapeutic modalities. Despite significant progress in ROS-based nanomedicines, there is a need to address fundamental principles for designing ROS-associated nanomedicines to minimize gaps in biomedical applications. This review summarizes current progress in ROS-associated nanomedicines in disease treatments and presents key principles for their design. Future perspectives in the development of ROS-associated nanomedicines are also discussed.
Review
Biotechnology & Applied Microbiology
Jiaxue Liu, Boyan Jia, Zhibo Li, Wenliang Li
Summary: Applying reactive polymer materials sensitive to biological stimuli has attracted extensive research interest. The application of reactive oxygen species (ROS)-responsive polymers as drug-delivery systems in organisms has received much attention due to the special physiological effects of ROS on tumors or inflammation. The research progress of ROS-responsive polymers and their application in recent years were summarized and analyzed in this paper. From the perspective of nanoparticle drug delivery systems, multi-responsive delivery systems, and ROS-responsive hydrogels, the future development trends in this field were discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Engineering, Environmental
Temoor Ahmed, Muhammad Noman, Natasha Manzoor, Shafaqat Ali, Muhammad Rizwan, Munazza Ijaz, Khaled S. Allemailem, Abdulkarim S. BinShaya, Fahad A. Alhumaydhi, Bin Li
Summary: Engineered nanomaterials have gained attention for their beneficial applications in various fields, but their use in agriculture may lead to NPs entering the environment, impacting the food chain. Barriers to implementation include safety concerns and efficient delivery. NPs interactions with ecosystems and their toxicity are global concerns.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Review
Chemistry, Analytical
Zhishun Jie, Jia Liu, Mingcong Shu, Ye Ying, Haifeng Yang
Summary: Reactive oxygen species (ROS) play a crucial role in regulating various physiological functions in living organisms, with superoxide anion being an important type of ROS closely related to many inflammatory diseases. In recent years, more detection techniques for superoxide anion have been developed as understanding of its role deepens in the field of biomedicine.
Review
Biochemistry & Molecular Biology
Silvia Piccirillo, Simona Magi, Alessandra Preziuso, Tiziano Serfilippi, Giorgia Cerqueni, Monia Orciani, Salvatore Amoroso, Vincenzo Lariccia
Summary: ROS have dual roles, acting as signaling molecules shaping physiological cell functions and as detrimental end products of unbalanced redox reactions. The brain is particularly vulnerable to ROS-mediated toxicity, which may influence the onset and progression of neurodegenerative diseases.
Review
Plant Sciences
Emily Medina, Su-Hwa Kim, Miriam Yun, Won-Gyu Choi
Summary: In natural ecosystems, plants constantly adapt to changes in their surroundings, with heat stress posing a risk to plant growth and development. Research has shown that plants respond to heat stress using complex signaling systems like ROS, which play a crucial role in promoting plant growth and triggering downstream reactions.
Review
Chemistry, Multidisciplinary
Si Chen, Piao Zhu, Lijie Mao, Wencheng Wu, Han Lin, Deliang Xu, Xiangyu Lu, Jianlin Shi
Summary: Emerging piezocatalysts show great potential in diverse medical fields. Apart from their high catalytic activities, their unique charge-carrier-releasing properties can initiate redox catalytic reactions, leading to promising medical applications. Piezocatalytic materials, triggered by mechanical energy, can promote the production of effector molecules for medical purposes, such as decontamination, sterilization, and therapy. The review provides an overview of the progress in piezocatalytic medicine, including the principle of piezocatalysis, preparation methods of piezoelectric materials, and medical applications in tumor treatment, antisepsis, organic degradation, tissue repair, regeneration, and biosensing. The challenges and future perspectives in piezocatalytic medicine are also discussed to fuel the development of this emerging discipline.
ADVANCED MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Kyung-Sook Chung, Chae-Bin Yoo, Jeong-Hun Lee, Hwi-Ho Lee, Sang-Eun Park, Hee-Soo Han, Su-Yeon Lee, Byoung-Mok Kwon, Jung-Hye Choi, Kyung-Tae Lee
Summary: The study shows that 2'-HCA induces apoptosis in HL-60 cells via activation of the ROS-dependent JNK pathway, suggesting its potential as a therapeutic agent for leukemia.
Review
Chemistry, Inorganic & Nuclear
Nahyun Kwon, Dayeh Kim, K. M. K. Swamy, Juyoung Yoon
Summary: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play crucial roles in human life, but overproduction can lead to cell damage and diseases. Researchers have developed fluorescent and luminescent probes based on metal-coordinated systems to detect and image these active species, providing valuable tools for studying their roles in signaling and pathology.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Gabriel T. Huynh, Vidhishri Kesarwani, Julia A. Walker, Jessica E. Frith, Laurence Meagher, Simon R. Corrie
Summary: The combination of nanomaterials and fluorescent detection offers new opportunities for monitoring oxygen and ROS in biological systems, improving optical properties and interactions with cells and media, and providing ratiometric sensing robust to environmental drift.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Physical
Patryk Szymaszek, Patrycja Sroda, Malgorzata Tyszka-Czochara, Anna Chachaj-Brekiesz, Tomasz Swiergosz, Joanna Ortyl
Summary: Here we report the synthesis of a novel fluorescent probe P182 for quantitative measurement of H2O2. This fluorometric probe displays a fluorescence turn-on response in the presence of H2O2. It offers good performances in terms of sensitivity and response time, and shows non-toxic activity for in vivo studies. This study provides research on molecular fluorescence probe for the detection of H2O2.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Organic
Yalan Wu, Wenyi Huang, Danfeng Peng, Xin-An Huang, Jiangyong Gu, Shengjun Wu, Tao Deng, Fang Liu
Summary: A mild synthetic method has been presented for preparing dihydroquinolines which have shown great potential for fluorescence detection of biorelevant hydroxyl radicals (center dot OH). One of the synthetic dihydroquinolines has been demonstrated to enable sensitive and selective detection of center dot OH and intracellular organelle-targeted fluorescence imaging. Dihydroquinoline also exhibits promising potential for constructing advanced fluorescence probes for center dot OH with tunable photophysical properties.
Review
Biochemistry & Molecular Biology
Aikaterini Berdiaki, Monica Neagu, Ioanna Spyridaki, Andrey Kuskov, Serge Perez, Dragana Nikitovic
Summary: Hyaluronan (HA) is a natural compound that is found on the cell surface and tissue extracellular matrix. It is synthesized by enzymes and degraded by other substances. HA has different effects on the body depending on its molecular weight, with high molecular weight HA being anti-inflammatory and low molecular weight HA being pro-inflammatory. Reactive oxygen species (ROS) can degrade HA and affect vascular integrity, while HA can also play a role in wound healing. Understanding the interactions between ROS and HA is an important research topic.
Article
Fisheries
Ratiporn Thongsoi, Siriluk Maskaew, Panumas Puechpon, Benjaporn Noppradit, Napassawan Inaek, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: In this study, a PPAE gene called FmPPAE1 was cloned and analyzed in banana shrimp. FmPPAE1 plays a vital role in regulating the proPO system, exhibits antibacterial properties, and contributes to the suppression of bacterial proliferation.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Jishuang Tan, Paizelaiti Sahaer, Huan Li, Wei Han, Hongyan Sun
Summary: Circular RNAs (circRNA) are involved in gene expression and affect cellular processes such as transcription, splicing, and translation by interacting with microRNA and RNA binding proteins. A study identified circDNAJB6 as a circular RNA abundant in chicken macrophages after bacterial infection, and found that circDNAJB6 exacerbates cellular injury and interacts with multiple miRNAs and target genes, potentially impacting autophagy and MAPK signaling pathways.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Rodrigo Guabiraba, Damaris Ribeiro Rodrigues, Paul T. Manna, Melanie Chollot, Vincent Saint-Martin, Sascha Trapp, Marisa Oliveira, Clare E. Bryant, Brian J. Ferguson
Summary: The innate immune response relies on the ability of host cells to detect and respond to microbial nucleic acids. Toll-like receptors (TLRs) play a crucial role in this process by distinguishing self from non-self. This study focused on TLR21, an avian TLR that recognizes bacterial DNA motifs. The findings suggest that avian TLR21 shares similar activation mechanisms to mammalian TLR9, highlighting the conservation of nucleic acid sensing mechanisms across species.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Safieh Zeinali, Kate Sutton, Lonneke Vervelde
Summary: Chickens have a unique immune structure characterized by the absence of draining lymph nodes and the presence of well-developed mucosa-associated lymphoid tissue. The structure and development of chicken lymphoid tissues in the intestine, particularly Peyer's patches, have been poorly studied. However, the use of CSF1R-eGFP reporter transgenic chickens has allowed for the visualization and investigation of the development and distribution of these tissues. This research provides insights that could benefit mucosal vaccination strategies and the development of targeted vaccine delivery systems.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Retraction
Fisheries
G. -g. Li, Z. -z. Guo, X. -f. Ma, N. Cao, S. -n. Geng, Y. -q. Zheng, M. -j. Meng, H. -h. Lin, G. Han, G. -j. Du
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Jinyue Yang, Peng Zhou, Wanrong Wu, Qingxiang Zhang, Dong Chen, Rui Luo
Summary: This study cloned and characterized the full-length sequence of duck MRE11 (duMRE11) for the first time, and found that this protein plays an important role in the innate immune response of ducks.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Mengjiao Guo, Jiaqi Zhang, Mingtao Li, Xiaorong Zhang, Yantao Wu
Summary: rNLRC3 negatively regulates the NF -KB signaling pathway induced by P. multocida in rabbits by inhibiting the activation of NF -KB, reducing the expression of inflammatory cytokines, and interacting with rTRAF4 and rTRAF6. The NACHT-LRR domain is the functional domain of rNLRC3. These findings provide insights into the important role of rNLRC3 in combating P. multocida infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Yinan Li, Xingye Lian, Wenwen Yang, Jinyuan Leng, Jiejie Sun, Yu Liu, Siqi Fan, Lingling Wang, Linsheng Song
Summary: The DM9-containing protein CgDM9CP-7 plays an important role in the innate immune response of molluscs. It is constitutively expressed in various tissues and is up-regulated in haemocytes after stimulation by Vibrio splendidus and lipopolysaccharide (LPS). CgDM9CP-7 binds to various pathogens and exhibits antimicrobial activity, while also regulating the expression of CgMyD88 and CgIL-17.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Xiuwen Bao, Haoran Song, Liying He, Yong Li, Shuqi Niu, Jinlin Guo
Summary: This study focuses on the interaction between Hepialus xiaojinensis larvae and Ophiocordyceps sinensis during the infection process. The results show that the infected third instar larvae enhance antioxidant defense ability, while the infected fourth instar larvae reduce this ability and allocate more energy to growth and development.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)