Article
Crystallography
Dmitriy F. Mertsalov, Rosa M. Gomila, Vladimir P. Zaytsev, Mikhail S. Grigoriev, Eugeniya Nikitina, Fedor Zubkov, Antonio Frontera
Summary: This paper reports the synthesis and X-ray characterization of two derivatives containing the four most abundant halogen atoms, aiming to study Ha···Ha halogen bonding interactions. The heavier halogen atoms exhibit anisotropy of electron density, leading to the formation of multiple Ha···Ha contacts in the solid state. The halogen bonding assemblies in both compounds were analyzed using various methods such as DFT calculations, MEP surfaces, QTAIM, NCIplot, and ELF.
Review
Biochemistry & Molecular Biology
Antonio Frontera, Antonio Bauza
Summary: This review gathers several examples of the application of pnictogen and chalcogen bonding interactions in organocatalytic processes, suggesting that it should be considered as a novel, promising tool in the field of organocatalysis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Inorganic & Nuclear
Thanthapatra Bunchuay, Andrew Docker, Nicholas G. White, Paul D. Beer
Summary: This study reports the synthesis of a series of halogen bonding acyclic anion receptors based on a novel 1,2-iodo-triazoliumtriazole benzene motif, and elucidates key conformational effects and coordination modes associated with ortho-substituted iodotriazole based XB donors through NMR spectroscopic techniques and X-ray crystal structure analysis.
Article
Chemistry, Multidisciplinary
Andrew Docker, Charles H. Guthrie, Heike Kuhn, Paul D. Beer
Summary: A series of acyclic anion receptors containing chalcogen bond (ChB) and halogen bond (XB) donors were described, showing a dramatic modulation in sigma-hole donor atom potency for anion recognition through systematic variation of the electronic-withdrawing nature of the aryl substituents. Incorporation of strongly electron-withdrawing perfluorophenyl units significantly enhanced the anion binding potency of the sigma-hole receptors, especially for ChB and XB receptors displaying over thirty-fold and eight-fold increase in chloride anion affinity, respectively. Linear free energy relationships for ChB based receptors revealed the halide anion recognition behavior of the tellurium donor is highly sensitive to local electronic environments, highlighting the opportunity to fine-tune anion affinity and selectivity in ChB-based receptor systems.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Biochemistry & Molecular Biology
Antonio Frontera, Antonio Bauza
Summary: This study shows that metal coordination can enhance the donor ability of chalcogen atoms, impacting solid state structures, and is therefore of significant importance to supramolecular chemists and solid state chemistry researchers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Alica C. Keuper, Kevin Fengler, Florian Ostler, Tobias Danelzik, Dariusz G. Piekarski, Olga Garcia Mancheno
Summary: A new approach to achieve highly enantioselective halogen-bonding catalysis has been developed by designing fine-tuned halogen-halogen interactions. This strategy utilizes both the electron cloud and sigma-hole site of the substrate's halogen substituent to form a tight chiral complex, enabling controlled induction of high levels of chirality transfer. Remarkable enantioselectivities of up to 95:5 e.r. (90% ee) have been achieved in a model dearomatization reaction using tetrakis-iodotriazole multidentate anion-binding catalysts.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Alexander Friedrich, Juergen Pahl, Jonathan Eyselein, Jens Langer, Nico van Eikema Hommes, Andreas Goerling, Sjoerd Harder
Summary: Complexes of Lewis base-free cations with Ph-X ligands were studied, showing that smaller ligands only form complexes with PhF while heavier ligands cannot compete with weakly coordinating anions, leading to Ph-X bond activation and elongation. The coordination of halogenated species to early main group metals is relevant to C-X bond breaking, and the Mg-X-Ph angle decreases with the size of X due to increasing sigma-hole from F to I.
Article
Chemistry, Inorganic & Nuclear
Chunyang Li, Anne-Doriane Manick, Jian Yang, David Givaudan, Bohdan Biletskyi, Sabine Michaud-Chevalier, Jean-Pierre Dutasta, Damien Herault, Xavier Bugaut, Bastien Chatelet, Alexandre Martinez
Summary: Chloroazaphosphatranes have been identified as a new class of halogen bond donors with modulable synthesis, showing comparable binding abilities to conventional iodine-based monodentate XB receptors and a relationship with the basicity of Verkade superbases. The strength of the XB interaction was revealed by the Delta delta(P-31) NMR shift observed in CD2Cl2 solution in the presence of triethylphosphine oxide (TEPO), expanding the repertory of XB motifs based on C-Ar-I bonds.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Hong-Ying Duan, Shi-Tao Han, Tian-Guang Zhan, Li-Juan Liu, Kang-Da Zhang
Summary: In this study, a visible-light-switchable telluro-triazole/triazolium-based chalcogen bonding system was demonstrated for the first time. The binding strength between the receptors and halide anions could be reversibly regulated by different wavelengths of visible light. The cis-bidentate receptor exhibited enhanced binding ability compared to the trans-monodentate receptor. The telluro-triazolium-based receptor showed both high and significantly photoswitchable binding affinities for halide anions, making it an efficient photocontrolled organocatalyst.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Multidisciplinary
Robert Hein, Paul D. Beer
Summary: Sigma-hole interactions, such as halogen bonding and chalcogen bonding, have wide-ranging applications in supramolecular chemistry, particularly in sensor design. This article provides a detailed overview of developments in XB and ChB mediated sensing, including optical and electrochemical sensors, and discusses the potential for future fundamental developments in the field. The concepts and methodologies described in this review are generically applicable for the development of supramolecular receptors and sensors, making it a useful guide for the chemistry community.
Article
Chemistry, Applied
Dhananjoy Pal, Tim Steinke, Lukas Vogel, Elric Engelage, Sascha Heinrich, Dana Kutzinski, Stefan M. Huber
Summary: This article describes the synthesis of a mixed chalcogen- and halogen-bond donor and provides a first indication of its catalytic activity in a benchmark reaction.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Andrew Docker, James G. Stevens, Paul D. Beer
Summary: A series of novel heteroditopic halogen bonding (XB) receptor functionalised silica-based materials are investigated for extracting sodium halide ion-pair species from aqueous solution. Cooperative XB-mediated sodium halide ion-pair binding is crucial to the material's extraction capabilities, showing a two-fold enhancement in sodium iodide extraction efficiency compared to other functionalised silica materials.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Shilin Yu, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen
Summary: Neutral halogen-bonded O-I-N complexes were prepared using carbonyl hypoiodites and aromatic organic bases. Modulating the Lewis basicity led to halogen-bonded complexes where the O-I...N bond transforms more into an asymmetric ion pair. X-ray analyses and NMR studies confirmed the geometries of the complexes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Alex Iglesias-Reguant, Judyta Zielak-Milewska, Tomasz Misiaszek, Robert Zalesny, Josep M. Luis, Borys Osmialowski
Summary: This study investigates the halogen-bonding interactions between a pyridine-functionalized fluoroborate dye and perfluorohaloarenes using fluorescence spectroscopy. The results indicate that only the complex formed between C6F5I and the emissive dye is stable, and halogen-bonding interactions lead to significant Stokes shifts for the pi pi * band. Experimental evidence also shows that the emission of this complex is suppressed due to a simultaneous decrease in radiative decay rate constant and an increase in nonradiative decay rate constant.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Edward J. Mitchell, Adam J. Beecroft, Jonathan Martin, Sally Thompson, Igor Marques, Vitor Felix, Paul D. Beer
Summary: By combining halogen bonding and coumarin fluorophore incorporation in acyclic host structural design, the first XB receptors capable of binding and sensing the hydrosulfide anion in pure water in a reversible chemosensing fashion have been demonstrated. These XB receptors exhibit characteristic selective quenching of fluorescence upon binding to HS-.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Inorganic & Nuclear
Pegah Hajivand, Johannes Carolus Jansen, Emilio Pardo, Donatella Armentano, Teresa F. Mastropietro, Amirreza Azadmehr
Summary: VOCs in human breath can be used as biomarkers for diseases, and MOFs have been extensively studied as gas sensors for VOCs. This review provides a comprehensive summary of the latest MOF-derived composites used as VOCs biomarkers' sensors, and discusses the structural and functional characteristics of MOFs, sensing properties, and the potential of bio-MOFs in VOCs sensing.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Seoyoon Song, Deborah Lee, Lucia C. Dalle Ore, Sungjun Kwak, Lifeng Kang, Hyung Kyo Kim, Noah Malmstadt, Sun Min Kim, Tae-Joon Jeon
Summary: This paper introduces the latest advancements in photoactivable liposomes in drug delivery, highlighting their advantages in precise control over drug release and targeted delivery, as well as the fine control over release kinetics achieved through the manipulation of light-responsive components. Additionally, the paper emphasizes the design considerations of physicochemical properties and light-related constituents.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shudi Liu, Liangwei Zhang, Heejeong Kim, Jinyu Sun, Juyoung Yoon
Summary: Chromium is a strategic and critical transition metal element with extensive applications. Efficient detection methods, such as fluorescence and colorimetry, have been developed for monitoring its concentrations. However, existing reviews on fluorescent probes for chromium lack comprehensive coverage. This review aims to consolidate information and promote the development of novel fluorescent probes for chromium detection.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rehab H. Elattar, Samah F. El-Malla, Amira H. Kamal, Fotouh R. Mansour
Summary: Metal complexes have strong analysis potential and can be used to measure analytes lacking essential chemical properties. Their analytical methods based on different mechanisms offer superior performance.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Nem Singh, Miae Won, Yunjie Xu, Changyu Yoon, Jiyoung Yoo, Mingle Li, Heemin Kang, Jong Seung Kim
Summary: Hypoxia is a common occurrence in the tumor microenvironment and poses challenges for cancer treatment. The introduction of covalent organic frameworks (COFs) offers promising prospects for addressing hypoxia-related issues. This article explores the role of COFs in enhancing oxygen delivery, generating reactive oxygen species, optimizing drug delivery, and enabling hypoxia-specific imaging, as well as outlining their applications in various hypoxia-targeting therapeutic modalities.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Priyadarshi Roy Chowdhury, Himani Medhi, Krishna G. Bhattacharyya, Chaudhery Mustansar Hussain
Summary: This review critically analyzes the production of waste-derived layered double hydroxides (LDH) and their utility in electrochemical water splitting for the generation of green hydrogen as sustainable energy. It highlights the importance of waste-derived LDH and discusses the challenges and future directions in this field.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rajamanickam Sivakumar, Nae Yoon Lee
Summary: This article reviews the progress in imaging reactive oxygen, nitrogen, and sulfur species (RONSS) using luminescent metal complex-based probes. This technology is selective and sensitive, which is of great significance for studying the impact of RONSS in cells and tissues and preventing diseases.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Xinyang Li, Binbin Ding, Pan Zheng, Ping'an Ma, Jun Lin
Summary: The main goal of immunotherapy is to enhance the response and cytotoxicity of tumor-specific T cells by turning cold tumors into hot tumors. However, metabolic reprogramming in the tumor microenvironment can depress the cytotoxicity of T cells and hinder the effectiveness of immunotherapy. This review discusses the role of metabolic reprogramming in the interplay between cancer cells and immune cells in the tumor microenvironment and explores the use of nanomaterials to modulate metabolic pathways and improve immunotherapy outcomes.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Kingsley Poon, Abhishek Gupta, William S. Price, Hala Zreiqat, Gurvinder Singh
Summary: Progress in the development of manganese oxide nanoparticles (MONPs) has provided an alternative for early-stage diagnosis of life-threatening diseases and therapeutic delivery of drugs and genes. The synthesis and characterization of MONPs have enabled the production of multi-functional targeted nanoparticles in various sizes and shapes. The integration of diagnosis and therapeutic capabilities within a single entity, known as nanotheranostics, is promising for real-time monitoring of disease progression and evaluating therapeutic treatment efficacy.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Reza Abedi-Firoozjah, Hadiseh Ebdali, Mahya Soltani, Parastoo Abdolahi-Fard, Mahshid Heydari, Elham Assadpour, Maryam Azizi-Lalabadi, Fuyuan Zhang, Seid Mahdi Jafari
Summary: With the increasing awareness of food safety, there is a growing demand for efficient and affordable sensing methods for the detection of pathogens and toxins in food products. Nanosensors offer promising solutions with their quick and reliable detection capabilities, although challenges remain in their fabrication and practical application.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Demei Sun, Xuesong Feng, Xinyuan Zhu, Youfu Wang, Jinghui Yang
Summary: Metal organic cages (MOCs) with precise and tunable nano structures show great potential in cancer therapy. Their diverse functions and ultrasmall size make them excellent nanoagents for different anticancer strategies, demonstrating outstanding anticancer performances.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Li Li, Yang-Tao Yu, Ning-Ning Zhang, Shu-Hao Li, Jian-Ge Zeng, Yang Hua, Hong Zhang
Summary: This article summarizes recent advances in POM-based hybrid photochromic materials (PCHPMs), including structure types, new photochromic mechanisms, and applications. It can provide valuable guidance for researchers investigating POM-based hybrid photochromic materials.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Chien Ing Yeo, Clariss Hui Peng Goh, Edward R. T. Tiekink, Jactty Chew
Summary: This review article provides an overview of the antibacterial activity of gold complexes, with a focus on gold(I) and gold(III) complexes. It also summarizes the repurposing of Auranofin for antibacterial purposes and the associated mechanism(s) of action.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Sangharaj Diyali, Nilankar Diyali, Bhaskar Biswas
Summary: This study discusses the recent progress in the design and development of catalysts, focusing on the factors influencing overpotential, catalytic rate, and stability, as well as the mechanisms of the hydrogen evolution reaction in acidic and alkaline media. Moreover, it outlines the challenges in future design of robust and active electrocatalysts.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shaik Gouse Peera, Rahul S. Menon, Sumanta Kumar Das, Akram Alfantazi, K. Karuppasamy, Chao Liu, Akhila Kumar Sahu
Summary: Doped carbon materials, especially F-doped carbon catalysts, have gained significant attention as metal-free catalysts for oxygen reduction reactions and as corrosion-resistant supports for Pt and non-Pt nanoparticles. F-doped carbon materials possess unique properties and greatly improve the activity and durability of the ORR compared to N-doped carbon materials. The high electronegativity of F-doping can efficiently modify the electronic band structure of carbon materials, favoring the ORR. This review systematically discusses the effect of F-doping/F co-doping on the electrocatalytic reduction of O2 in acidic and alkaline conditions, the stability and durability of fuel cell catalysts, and provides guidelines for working with F-doped carbons. Future research directions on F-doped carbons are also proposed to bridge the gap between laboratory-scale assessments and commercial applications.
COORDINATION CHEMISTRY REVIEWS
(2024)