Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

Published 2020 View Full Article

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Title
Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
Authors
Keywords
natural killer cells, iPSCs, CISH, cell therapy, immunotherapy, acute myelogenous leukemia, metabolic reprograming, IL-15, mTOR, JAK-STAT
Journal
Cell Stem Cell
Volume 27, Issue 2, Pages 224-237.e6
Publisher
Elsevier BV
Online
2020-06-11
DOI
10.1016/j.stem.2020.05.008

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