Journal
CELL CALCIUM
Volume 88, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ceca.2020.102212
Keywords
TPC2; TPC; Two-pore channel; Covid-19; SARS-CoV2; Lysosome
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Funding
- German Research Foundation DFG [SFB/TRR152, GR-4315/4-1]
- NCL Stiftung, Hamburg, Germany
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The ongoing SARS-CoV2 outbreak has developed into a global pandemic. Despite previous outbreaks of SARS-CoV and the related MERS-CoV in recent years, neither a vaccine nor any other medication for an effective treatment are currently available. Endo-lysosomal two-pore cation channels have now emerged as potential novel targets for SARS-CoV treatment.
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