Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2

Published 2020 View Full Article

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Title
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2
Authors
Keywords
Niemann-Pick disease type C, NPC1, NPC2, lysosomal cholesterol egress, cholesterol transport, cryo-EM, structural biology
Journal
CELL
Volume 182, Issue 1, Pages 98-111.e18
Publisher
Elsevier BV
Online
2020-06-15
DOI
10.1016/j.cell.2020.05.020

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