4.2 Review

Inpatient Treatment of Functional Neurological Disorder: A Scoping Review

Journal

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Volume 48, Issue 2, Pages 204-217

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1017/cjn.2020.159

Keywords

Functional neurological disorder; Functional movement disorder; Psychogenic movement disorder; Inpatient rehabilitation; Treatment

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This scoping review summarizes literature on characteristics of patients admitted to hospitals for functional neurological disorder treatment, finding that motor symptoms are most common and interventions usually involve physiotherapy and psychotherapy. Most studies report partial or complete symptom resolution.
Background: The aim of this scoping review is to describe the characteristics of patients requiring admission to hospital for functional neurological disorder (FND), assess interventions provided, and evaluate outcomes in the context of acute hospital presentation or elective admission with chronic symptoms (>3 months). Methods: A scoping review was performed. Included articles described adult patients admitted with FND to an inpatient care setting. Articles focusing on psychogenic non-epileptic attacks (PNEA) were excluded. Results: The search strategy identified 1963 citations. A total of 34 articles met inclusion criteria, with 458 patients (66% female) described. The pooled mean age of patients in all studies was 40.6 years. Eleven studies described patients with acute presentation, and 16 studies described patients with chronic FND symptoms admitted to the hospital. Motor symptoms were most common. Interventions were most commonly physiotherapy and psychotherapy. Most studies reported partial or complete resolution of symptoms. Conclusions: This scoping review summarizes the literature on the characteristics of patients admitted to the hospital, both with acute and chronic symptoms, for inpatient treatment of FND. When comparing patients with acute to those with chronic symptoms, we found that acute presentations were older (46.9 vs. 43.7 years) and had a higher representation of men (33% vs. 30%). Those presenting with chronic symptoms were more likely to not improve or relapse. We postulate that early diagnosis and inpatient rehabilitation could have a positive impact on outcomes for patients with FND.

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