A chalcone derivative, 1m‐6, exhibits atheroprotective effects by increasing cholesterol efflux and reducing inflammation‐induced endothelial dysfunction

Specific Disruption of Abca1 Targeting Largely Mimics the Effects of miR-33 Knockout on Macrophage Cholesterol Efflux and Atherosclerotic Plaque Development

(2019) Nathan L. Price et al.   CIRCULATION RESEARCH

Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology

(2018) Steve P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

(2018) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial infarction

(2018) Carol W Chen et al.   CARDIOVASCULAR RESEARCH

Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages

(2018) I-Jou Teng et al.   MOLECULES

Epigallocatechin-3-gallate Reduces Scavenger Receptor A Expression and Foam Cell Formation in Human Macrophages

(2017) Sy-Jou Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The immunology of atherosclerosis

(2017) Anton Gisterå et al.   Nature Reviews Nephrology

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma

(2017) Y-S Liu et al.   ONCOGENE

Novel indolyl-chalcone derivatives inhibit A549 lung cancer cell growth through activating Nrf-2/HO-1 and inducing apoptosis in vitro and in vivo

(2017) Xuan Zhao et al.   Scientific Reports

Micro-RNAs and High-Density Lipoprotein MetabolismHighlights

(2016) Alberto Canfrán-Duque et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Targeting vascular (endothelial) dysfunction

(2016) Andreas Daiber et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of trans-chalcone on atheroma plaque formation, liver fibrosis and adiponectin gene expression in cholesterol-fed NMRI mice

(2016) Leyla Karkhaneh et al.   Pharmacological Reports

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

(2016) Nader G. Abraham et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1

(2015) Yun-cheng Lv et al.   ATHEROSCLEROSIS

The inhibitory effects of xanthohumol, a prenylated chalcone derived from hops, on cell growth and tumorigenesis in human pancreatic cancer

(2015) Weiliang Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

BJP is linking its articles to the IUPHAR/BPS Guide to PHARMACOLOGY

(2015) J C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: Role of TRPV1, oxidative stress, cytokines and NF-κB

(2015) Felipe A. Pinho-Ribeiro et al.   CHEMICO-BIOLOGICAL INTERACTIONS

MicroRNAs in cardiovascular disease: an introduction for clinicians

(2015) Simon P R Romaine et al.   HEART

Attenuation of inflammatory response by a novel chalcone protects kidney and heart from hyperglycemia-induced injuries in type 1 diabetic mice

(2015) Qilu Fang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

microRNAs and HDL life cycle

(2014) A. Canfran-Duque et al.   CARDIOVASCULAR RESEARCH

Molecular Mechanisms of Cellular Cholesterol Efflux

(2014) Michael C. Phillips   JOURNAL OF BIOLOGICAL CHEMISTRY

HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

(2014) Anand Rohatgi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145

(2013) Martin H. Kang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Design, synthesis and evaluation of novel indole derivatives as AKT inhibitors

(2013) Dezhi Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1

(2013) Zhiping Liu et al.   JOURNAL OF LIPID RESEARCH

Evaluation of the Anti-Inflammatory Effect of Chalcone and Chalcone Analogues in a Zebrafish Model

(2013) Yau-Hung Chen et al.   MOLECULES

Diversifying microRNA sequence and function

(2013) Stefan L. Ameres et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells

(2013) L. Baselga-Escudero et al.   NUCLEIC ACIDS RESEARCH

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Heme Oxygenase-1 Inhibits Myoblast Differentiation by Targeting Myomirs

(2011) Magdalena Kozakowska et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

(2011) Cristina M. Ramirez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

(2011) Vinay Bhaskar et al.   ATHEROSCLEROSIS

Viscolin reduces VCAM-1 expression in TNF-α-treated endothelial cells via the JNK/NF-κB and ROS pathway

(2011) Chan-Jung Liang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1

(2010) Jin-Yi Tsai et al.   CARDIOVASCULAR RESEARCH

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs

(2009) Subhash Padhye et al.   Journal of Hematology & Oncology

25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway

(2008) Yongjie Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation

(2008) Megumi Funakoshi-Tago et al.   BIOCHEMICAL PHARMACOLOGY

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

Cinnamaldehyde inhibits the tumor necrosis factor-α-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-κB activation: Effects upon IκB and Nrf2

(2008) Being-Chyuan Liao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY