Review
Anesthesiology
Lu Wang, Meng Yang, Wangtao Meng
Summary: This systematic review and meta-analysis investigated the prevalence and characteristics of persistent postoperative pain (PPP) after thoracic surgery. The results showed that 38.1% of thoracic surgery patients developed PPP, with 40.6% experiencing moderate-to-severe pain and 56.5% requiring opioid analgesics. Therefore, adequate pain treatment and follow-up are needed for patients undergoing thoracic surgery.
ANESTHESIA AND ANALGESIA
(2023)
Article
Anesthesiology
Ciara Hanley, Karim S. Ladha, Hance A. Clarke, Brian C. Cuthbertson, Duminda N. Wijeysundera
Summary: Postoperative complications are associated with post-surgical pain, and the occurrence of major complications increases the likelihood of patients reporting pain at 30 days and possibly 1 year after surgery.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Review
Anesthesiology
Zhengyang Liu, Alexandra D. Karamesinis, Mark Plummer, Reny Segal, Rinaldo Bellomo, Julian A. Smith, Luke A. Perry
Summary: Persistent postoperative opioid use after cardiac surgery affects at least one in 20 patients. Risk factors such as female sex, smoking, alcohol use, congestive cardiac failure, diabetes mellitus, chronic lung disease, chronic kidney disease, and length of hospital stay are associated with this phenomenon.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Oncology
Masahiro Manfuku, Tomohiko Nishigami, Akira Mibu, Hirofumi Yamashita, Ryota Imai, Hiroe Kanamori, Kazuhiro Sumiyoshi
Summary: This study found that axillary lymph node dissection (ALND) and 1-month postoperative central sensitization (CS)-related symptoms were predictors of persistent post-surgical pain (PPSP) intensity and interference at 1 year postoperatively.
Review
Anesthesiology
Joshua Lim, Dili Chen, Ewan McNicol, Lokesh Sharma, Grihith Varaday, Anshuman Sharma, Elizabeth Wilson, Tiffany Wright-Yatsko, Lauren Yaeger, Ian Gilron, Nanna B. Finnerup, Simon Haroutounian
Summary: This study systematically reviewed the literature on risk factors of Persistent postsurgical pain (PPSP) after breast and thoracic surgeries and identified consistent factors. Understanding these factors can help optimize perioperative care in high-risk patients and develop targeted, risk-stratified interventions for PPSP prevention.
Review
Anesthesiology
Vahid Ashoorion, Behnam Sadeghirad, Li Wang, Atefeh Noori, Meisam Abdar, Yechan Kim, Yaping Chang, Nadia Rehman, Luciane C. Lopes, Rachel J. Couban, Mahmood Aminilari, Alireza Malektojari, Sara Ghazizadeh, Yasir Rehman, Mehdi Ghasemi, Anthony Adili, Gordon H. Guyatt, Jason W. Busse
Summary: Approximately one in four total knee replacement patients develop persistent pain. Factors such as pain catastrophizing, younger age, and moderate-to-severe acute post-operative pain are associated with persistent pain after knee replacement surgery, while sex and higher pre-operative pain may also play a role.
Review
Dentistry, Oral Surgery & Medicine
Leanne Teoh, Michael McCullough, Meng-Wong Taing
Summary: This article aims to evaluate the effectiveness of oxycodone for acute dental pain. The systematic review and meta-analysis found that oxycodone, when combined with paracetamol, provides better analgesia. However, compared to non-steroidal anti-inflammatory drugs, oxycodone is less effective.
JOURNAL OF DENTISTRY
(2022)
Article
Surgery
Rathnayaka M. K. D. Gunasingha, Injamamul L. Niloy, Berish B. Wetstein, Peter A. Learn, Lauren C. Turza
Summary: This study investigated postoperative opioid usage among patients undergoing breast surgeries and recommended a set number of opioid pills for discharge. The results indicate that most breast surgery patients can be discharged with fewer than 10 opioid pills, except under special circumstances. Utilization of a standardized discharge opioids protocol can effectively reduce the number of opioids prescribed to patients.
Review
Oncology
Philip J. Chang, Arash Asher, Sean R. Smith
Summary: There are various causes of pain following treatment for breast cancer, including nerve damage and musculoskeletal system problems. Precise diagnosis of the pain generators is essential for directing appropriate treatment.
Review
Surgery
Hala Muaddi, Erin Lillie, Stephanie Silva, Jori-Lee Cross, Karim Ladha, Stephen Choi, Aaron Mocon, Paul Karanicolas
Summary: This study systematically reviewed and meta-analyzed the effects of cryotherapy on closed incisions. The results showed that cryotherapy can significantly reduce postoperative pain and opioid consumption. However, it has no effect on hospital length of stay or surgical site infection rate.
Review
Anesthesiology
Min Xie, Yu Liang, Yan Deng, Tao Li
Summary: This systematic review and meta-analysis evaluated the risk of post-abdominal surgery pain in adults who were administered perioperative S-ketamine. The results showed that S-ketamine effectively reduced early postoperative pain at rest and during movement, without increasing the incidence of postoperative complications. The mode and timing of S-ketamine administration also influenced the pain scores differently.
Article
Anesthesiology
Xiao Deng, Hao Li, Yantong Wan, Xuemei Lin
Summary: This meta-analysis found that pulmonary recruitment maneuver (PRM) is beneficial in alleviating post-laparoscopic shoulder pain (PLSP), based on the analysis of 14 studies involving 1504 patients.
BMC ANESTHESIOLOGY
(2023)
Review
Obstetrics & Gynecology
Mojdeh Banaei, Nourossadat Kariman, Giti Ozgoli, Maliheh Nasiri, Vida Ghasemi, Azam Khiabani, Sareh Dashti, Leila Mohamadkhani Shahri
Summary: In a meta-analysis of 22 studies enrolling 11,457 women of reproductive age, the overall estimated prevalence of dyspareunia was 35%. This prevalence decreased with increasing postpartum duration, highlighting the importance of paying special attention to this common complaint during the postpartum period.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Review
Medicine, General & Internal
Pascal Richard David Clephas, Sanne Elisabeth Hoeks, Marialena Trivella, Christian S. Guay, Preet Mohinder Singh, Markus Klimek, Michael Heesen
Summary: This study aims to summarize the evidence on prognostic factors for chronic post-surgical pain after lung or pleural surgery through systematic reviews and meta-analyses, in order to understand the influencing factors. A large number of relevant studies will be searched and evaluated, with quality assessment and data extraction conducted based on standardized criteria.
Review
Anesthesiology
Taalke Sitter, Patrice Forget
Summary: The proportion of persistent postoperative opioid use in European countries is not well-established, as different studies show varying results. It is not possible to describe persistent opioid use in relation to specific countries or types of surgery due to the wide ranges observed.
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
(2021)
Review
Allergy
Juan Jose Yepes-Nunez, Gordon H. Guyatt, Luis Guillermo Gomez-Escobar, Lucia C. Perez-Herrera, Alexandro W. L. Chu, Renata Ceccaci, Ana Sofia Acosta-Madiedo, Aaron Wen, Sergio Moreno-Lopez, Margaret MacDonald, Monica Barrios, Xiajing Chu, Nazmul Islam, Ya Gao, Melanie M. Wong, Rachel Couban, Elizabeth Garcia, Edgardo Chapman, Paul Oykhman, Lina Chen, Tonya Winders, Rachel Netahe Asiniwasis, Mark Boguniewicz, Anna De Benedetto, Kathy Ellison, Winfred T. Frazier, Matthew Greenhawt, Joey Huynh, Elaine Kim, Jennifer LeBovidge, Mary Laura Lind, Peter Lio, Stephen A. Martin, Monica O'Brien, Peck Y. Ong, Jonathan I. Silverberg, Jonathan Spergel, Julie Wang, Kathryn E. Wheeler, Lynda Schneider, Derek K. Chu
Summary: This article summarizes the evidence regarding the benefits and harms of allergen immunotherapy (AIT) for atopic dermatitis (AD). The findings indicate that subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) can significantly improve the severity and quality of life of AD patients, but they may also increase adverse events. Therefore, a multidisciplinary and shared decision-making approach should be adopted for optimal management of AD.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ganesan Karthikeyan, Amalia Peix, Niveditha Devasenapathy, Amelia Jimenez-Heffernan, Saif-Ul Haque, Carlo Rodella, Raffaele Giubbini, Erick Alexanderson Rosas, Elgin Ozkan, Yung Jih Felix Keng, Joao Vitola, Dragana Sobic-Saranovic, Manoj Soni, Leonardo Lopez, Lazaro O. Cabrera, Santiago Camacho-Freire, Ana Manovel-Sanchez, Hesham Naeem, Shazia Fatima, Roberto Rinaldi, Isabel Carvajal-Juarez, Kerim Esenboga, Maurizio Dondi, Diana Paez
Summary: This study compared the efficacy and safety of ischemia-guided non-culprit vessel angioplasty with routine non-culprit vessel angioplasty in patients with multi-vessel disease presenting with ST elevation myocardial infarction (STEMI). The results showed that ischemia-guided non-culprit PCI resulted in low ischemia burden and was equally effective as routine non-culprit vessel PCI in reducing ischemia burden. This approach may offer cost-savings, particularly in low-resource settings.
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Abdul Rehman Qureshi, Oluwatoni Makanjuola, Samuel Neumark, Andrew Garas, Li Wang, Jason W. Busse
Summary: The study identified research priorities among Canadian military veterans with chronic noncancer pain, including optimizing pain management after release, establishing the effectiveness of self-care, and identifying and treating mental illness in veterans with chronic pain. The importance of improving chronic pain care while in the military was rated higher by females.
Review
Pediatrics
Niveditha Devasenapathy, Alexandro Chu, Melanie Wong, Archita Srivastava, Renata Ceccacci, Clement Lin, Margaret MacDonald, Aaron Wen, Jeremy Steen, Mitchell Levine, Lonnie Pyne, Lynda Schneider, Derek K. Chu
Summary: This study systematically reviewed the risk of cancer in patients with atopic dermatitis using topical calcineurin inhibitors. The analysis of 110 studies found no significant association between the use of topical calcineurin inhibitors and cancer risk. These findings support the safe use of topical calcineurin inhibitors in the treatment of patients with atopic dermatitis.
LANCET CHILD & ADOLESCENT HEALTH
(2023)
Article
Health Care Sciences & Services
Yuting Wang, Tahir Devji, Alonso Carrasco-Labra, Anila Qasim, Qiukui Hao, Elena Kum, Niveditha Devasenapathy, Madeleine T. King, Berend Terluin, Caroline B. Terwee, Michae Walsh, Toshi A. Furukawa, Yasushi Tsujimoto, Gordon H. Guyatt
Summary: The minimal important difference (MID) is the smallest change or difference that patients perceive as important to interpret patient-reported outcome measure (PROM) scores. A credibility instrument for anchor-based MID assessment typically includes a core item evaluating the correlation between the PROM and the anchor. However, many MID studies do not report this correlation. To address this, we developed an alternative construct proximity item to assess credibility when the correlation is lacking.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Review
Surgery
Jian-jun Xue, Yi-yang Cui, Jason W. Busse, Long Ge, Ting Zhou, Wei-hua Huang, Sheng-shuang Ding, Jie Zhang, Ke-hu Yang
Summary: A systematic review showed that transversus thoracic muscle plane blocks (TTMPBs) during cardiac surgery can reduce postoperative pain at rest and with movement, opioid consumption, ICU length of stay, and the incidence of nausea and vomiting.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Rehabilitation
Sabhya Pritwani, Shruti Pandey, Purnima Shrivastava, Ajit Kumar, Rajesh Malhotra, Ralph Maddison, Niveditha Devasenapathy
Summary: This study aims to understand the postoperative experiences of patients following unsupervised home-based physiotherapy protocols and the experiences of healthcare providers in providing rehabilitation care. The findings reveal that patients desire physiotherapy support, particularly during the early recovery period, while healthcare providers want a mechanism to monitor patient progress after discharge. Both patients and healthcare providers identified accessibility to rehabilitation centers as a major barrier in accessing affordable and reliable physiotherapy services.
DISABILITY AND REHABILITATION
(2023)
Article
Health Care Sciences & Services
Linan Zeng, Shelly-Anne Li, Mengting Yang, Lijiao Yan, Lise M. Helsingen, Michael Bretthauer, Thomas Agoritsas, Per O. Vandvik, Reem A. Mustafa, Jason Busse, Reed A. C. Siemieniuk, Lyubov Lytvyn, Lingli Zhang, Romina Brignardello-Petersen, Gordon H. Guyatt
Summary: This study explores guideline panelists' understanding of panel surveys in eliciting patient values and preferences, and their influence on making recommendations. The results show that most panelists found the survey easy to follow and that it helped incorporate patient values and preferences in the tradeoffs, enhancing the rationale behind the decisions.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Review
Medicine, General & Internal
Mansi Patel, Jane Jomy, Rachel J. Couban, Helene Le Scelleur, Jason W. Busse
Summary: This review examines the challenges and transition needs of military personnel living with chronic pain as they return to civilian life. The study identified several challenges in areas such as identity, interpersonal interactions, employment, education, finances, self-care and mental health, and accessing services and care. However, there is a lack of specific research on individuals released with chronic pain, highlighting the need for further studies to address their unique needs and well-being.
Letter
Anesthesiology
Jared C. Cohen, Anthony M. -H. Ho, Heather D. O'Reilly, Glenio B. Mizubuti
BRAZILIAN JOURNAL OF ANESTHESIOLOGY
(2023)
Review
Medicine, General & Internal
Yasir Rehman, Malgorzata Bala, Nadia Rehman, Arnav Agarwal, Magdalena Koperny, Holly Crandon, Ream Abdullah, Alexandra Hull, Nima Makhdami, Savannah Grodecki, Anna Wrzosek, Wiktoria Lesniak, Nathan Evaniew, Vahid Ashoorion, Li Wang, Rachel Couban, Brian Drew, Jason W. Busse
Summary: This study conducted a systematic review to explore factors associated with chronic post-surgical leg pain and impairments after lumbar microdiscectomy for sciatica. The results showed that female sex is likely associated with persistent leg pain and failure to return to work, and older age is probably associated with greater post-surgical disability. Future research should investigate the association between legal representation and preoperative opioid use with persistent pain and impairment after microdiscectomy for sciatica.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Meeting Abstract
Allergy
Alexandro Chu, Niveditha Devasenapathy, Melanie Wong, Archita Srivastava, Clement Lin, Renata Ceccacci, Margaret Mac-Donald, Derek Chu
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Primary Health Care
Meenakshi Tomar, Tarika Sharma, Manya Prasad
Summary: This study assessed the social challenges faced by Hepatitis B-positive patients seeking treatment at a super specialty liver hospital, and found that these patients face social challenges in terms of lack of awareness, psychological issues, and stigmatization by healthcare providers, family members, and colleagues at their workplace. Therefore, a holistic approach is needed to treat patients with Hepatitis B.
JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE
(2023)
Article
Public, Environmental & Occupational Health
Kumar Dushyant, Gagandeep Kaur Walia, Niveditha Devasenapathy
Summary: This study highlights the respiratory burden among vulnerable informal workers exposed to cement dust. Urgent policy reforms are needed to safeguard the occupational health of informal workers.
ANNALS OF GLOBAL HEALTH
(2023)
Review
Medicine, General & Internal
Li Wang, Patrick J. Hong, Wenjun Jiang, Yasir Rehman, Brian Y. Hong, Rachel J. Couban, Chunming Wang, Corey J. Hayes, David N. Juurlink, Jason W. Busse
Summary: This study identified 10 predictors strongly associated with opioid overdose, including a history of overdose, higher opioid dose, multiple prescribers, multiple dispensing pharmacies, prescription of fentanyl, current substance use disorder, any mental health diagnosis, depression, bipolar disorder, and pancreatitis. Awareness of these predictors may facilitate shared decision-making regarding opioid prescribing for chronic pain and inform harm-reduction strategies.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2023)