Update on multi‐gene panel testing and communication of genetic test results

Therapeutic implications of germline genetic findings in cancer

(2019) Subotheni Thavaneswaran et al.   Nature Reviews Clinical Oncology

An update on genetic risk assessment and prevention: the role of genetic testing panels in breast cancer

(2019) Carolyn Piccinin et al.   Expert Review of Anticancer Therapy

Tumor Genomic Sequencing as an Impetus to Screen for Germline Mutations: Primum Non Nocere

(2019) Saroj Niraula   Journal of Oncology Practice

When Should Tumor Genomic Profiling Prompt Consideration of Germline Testing?

(2019) Kim DeLeonardis et al.   Journal of Oncology Practice

Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium

(2019) Pooja Middha Kapoor et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Maternal perceptions of BRCA genetic counseling communication processes about disclosing cancer risk information to children and adult relatives

(2018) Jada G. Hamilton et al.   PSYCHO-ONCOLOGY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Prevalence of Variant Reclassification Following Hereditary Cancer Genetic Testing

(2018) Jacqueline Mersch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation

(2018) Jennifer K. Litton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Breast Cancer Surgical Risk Reduction for Patients With Inherited Mutations in Moderate Penetrance Genes

(2018) Anna Weiss et al.   JAMA Surgery

Clinical validity assessment of genes frequently tested on hereditary breast and ovarian cancer susceptibility sequencing panels

(2018) Kristy Lee et al.   GENETICS IN MEDICINE

Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?

(2018) Peter D. Beitsch et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutations in context: implications of BRCA testing in diverse populations

(2017) Gabriela E. S. Felix et al.   Familial Cancer

Racial/ethnic differences in multiple-gene sequencing results for hereditary cancer risk

(2017) Jennifer L Caswell-Jin et al.   GENETICS IN MEDICINE

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing

(2017) Diana Mandelker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

(2017) Karoline B. Kuchenbaecker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

(2017) Julie Lecarpentier et al.   JOURNAL OF CLINICAL ONCOLOGY

National Estimates of Genetic Testing in Women With a History of Breast or Ovarian Cancer

(2017) Christopher P. Childers et al.   JOURNAL OF CLINICAL ONCOLOGY

Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

(2017) Fergus J. Couch et al.   JAMA Oncology

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

(2017) Dezheng Huo et al.   JAMA Oncology

Gene Panel Testing for Inherited Cancer Risk

(2017) Michael J. Hall et al.   Journal of the National Comprehensive Cancer Network

Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol

(2016) F. Meric-Bernstam et al.   ANNALS OF ONCOLOGY

Risks of first and subsequent cancers amongTP53mutation carriers in the National Cancer Institute Li-Fraumeni syndrome cohort

(2016) Phuong L. Mai et al.   CANCER

Care delivery considerations for widespread and equitable implementation of inherited cancer predisposition testing

(2016) Deborah Cragun et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics

(2016) Sarah S. Kalia et al.   GENETICS IN MEDICINE

Psychosocial and Clinical Factors Associated with Family Communication of Cancer Genetic Test Results among Women Diagnosed with Breast Cancer at a Young Age

(2016) Ashley Elrick et al.   Journal of Genetic Counseling

Counselling framework for moderate-penetrance cancer-susceptibility mutations

(2016) Nadine Tung et al.   Nature Reviews Clinical Oncology

Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA

(2016) Kasmintan A. Schrader et al.   JAMA Oncology

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

(2015) Mark E. Robson et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

(2015) Douglas F. Easton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Personalized genomic analyses for cancer mutation discovery and interpretation

(2015) Siân Jones et al.   Science Translational Medicine

Next-Generation Sequencing for Inherited Breast Cancer Risk: Counseling through the Complexity

(2014) Irene R. Rainville et al.   Current Oncology Reports

Breast cancer genes: beyond BRCA1 and BRCA2

(2013) Ana Vega   Frontiers in Bioscience-Landmark

Risk of Breast Cancer in Women With a CHEK2 Mutation With and Without a Family History of Breast Cancer

(2011) Cezary Cybulski et al.   JOURNAL OF CLINICAL ONCOLOGY

Communication of BRCA Results and Family Testing in 1,103 High-Risk Women

(2010) E. L. Cheung et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Breast Cancer in the Personal Genomics Era

(2010) Rachel E. Ellsworth et al.   CURRENT GENOMICS

Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

(2010) Susan M. Domchek   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The emerging landscape of breast cancer susceptibility

(2007) Michael R Stratton et al.   NATURE GENETICS