Detection of leukemia gene fusions by targeted RNA-sequencing in routine diagnostics

Comparison of Four Next Generation Sequencing Platforms for Fusion Detection: Oncomine by ThermoFisher, AmpliSeq by Illumina, FusionPlex by ArcherDX, and QIAseq by QIAGEN

(2020) Xiaoyu Qu et al.   Cancer Genetics

Detection of recurrent and of novel fusion transcripts in myeloid malignancies by targeted RNA sequencing

(2018) Anna Stengel et al.   LEUKEMIA

Clinical Evaluation of Massively Parallel RNA Sequencing for Detecting Recurrent Gene Fusions in Hematologic Malignancies

(2018) Borahm Kim et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The MLL recombinome of acute leukemias in 2017

(2017) C Meyer et al.   LEUKEMIA

Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia

(2017) Sadia Afrin et al.   MOLECULAR CANCER RESEARCH

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

(2016) Henrik Lilljebjörn et al.   Nature Communications

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Guidelines for diagnostic next-generation sequencing

(2015) Gert Matthijs et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

(2015) Anna K Andersson et al.   NATURE GENETICS

Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors

(2015) Marina N. Nikiforova et al.   NEURO-ONCOLOGY

ChildSeq-RNA

(2014) Mohammed A. Qadir et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Comparison between Karyotyping-FISH-Reverse Transcription PCR and RNA- Sequencing-Fusion Gene Identification Programs in the Detection of KAT6A-CREBBP in Acute Myeloid Leukemia

(2014) Ioannis Panagopoulos et al.   PLoS One

European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013

(2013) M. Baccarani et al.   BLOOD

RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib

(2013) H Lilljebjörn et al.   LEUKEMIA

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Sensitivity of minimal residual disease in acute myeloid leukaemia in first remission - methodologies in relation to their clinical situation

(2012) Peter Hokland et al.   BRITISH JOURNAL OF HAEMATOLOGY

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

(2012) Jolanta Grembecka et al.   Nature Chemical Biology

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

(2011) Scott R. Daigle et al.   CANCER CELL

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases

(2010) Marketa Zaliova et al.   PEDIATRIC BLOOD & CANCER