New insights into the Manila clam and PAMPs interaction based on RNA-seq analysis of clam through in vitro challenges with LPS, PGN, and poly(I:C)

Transcriptome analysis of the hippocampus in environmental noise-exposed SAMP8 mice reveals regulatory pathways associated with Alzheimer’s disease neuropathology

(2020) Donghong Su et al.   Environmental Health and Preventive Medicine

Transcriptome analysis reveals differential immune related genes expression in Ruditapes philippinarum under hypoxia stress: potential HIF and NF-κB crosstalk in immune responses in clam

(2020) Hongtao Nie et al.   BMC GENOMICS

A review of transgenerational effects of ocean acidification on marine bivalves and their implications for sclerochronology

(2020) Liqiang Zhao et al.   ESTUARINE COASTAL AND SHELF SCIENCE

Transcriptomic analysis of Ruditapes philippinarum under aerial exposure and reimmersion reveals genes involved in stress response and recovery capacity of the Manila clam

(2020) Hongtao Nie et al.   AQUACULTURE

Derivatives of the lectin complement pathway in Lophotrochozoa

(2019) Alexander M. Gorbushin   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Comparative Genome and Transcriptome Study of the Gene Expression Difference Between Pathogenic and Environmental Strains of Prototheca zopfii

(2019) Xuanhao Zeng et al.   Frontiers in Microbiology

Molecular characterization and expression analysis of fibrinogen related protein (FREP) genes of Manila clam (Ruditapes philippinarum) after lipopolysaccharides challenge

(2019) Dongdong Li et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

The oyster immunity

(2018) Lingling Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum : Investigation of the antibacterial activities and mode of action

(2018) Dinglong Yang et al.   FISH & SHELLFISH IMMUNOLOGY

Analyzing AbrB-Knockout Effects through Genome and Transcriptome Sequencing of Bacillus licheniformis DW2

(2018) Cheng-Cheng Shu et al.   Frontiers in Microbiology

Molecular cloning and expression analysis of C-type lectin (RpCTL) in Manila clam Ruditapes philippinarum after lipopolysaccharide challenge

(2018) Dongdong Li et al.   FISH & SHELLFISH IMMUNOLOGY

Transcriptome analysis of Ruditapes philippinarum hepatopancreas provides insights into immune signaling pathways under Vibrio anguillarum infection

(2017) Yipeng Ren et al.   FISH & SHELLFISH IMMUNOLOGY

The Whole-Genome and Transcriptome of the Manila Clam (Ruditapes philippinarum)

(2017) Seyoung Mun et al.   Genome Biology and Evolution

Bias and Correction in RNA-seq Data for Marine Species

(2017) Kai Song et al.   MARINE BIOTECHNOLOGY

Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins

(2017) Yuli Li et al.   Nature Communications

RNA-Seq analysis of salinity stress–responsive transcriptome in the liver of spotted sea bass (Lateolabrax maculatus)

(2017) Xiaoyan Zhang et al.   PLoS One

Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata

(2016) Si-Ming Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A new non-phagocytic TLR6 with broad recognition ligands from Pacific oyster Crassostrea gigas

(2016) Weilin Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Insect-derived short proline-rich and murine cathelicidin-related antimicrobial peptides act synergistically on Gram-negative bacteria in vitro

(2016) Daniel Knappe et al.   Future Medicinal Chemistry

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Transcriptome Analysis and Gene Identification in the Pulmonary Artery of Broilers with Ascites Syndrome

(2016) Fei Yang et al.   PLoS One

RNA-Seq in Mytilus galloprovincialis: comparative transcriptomics and expression profiles among different tissues

(2015) Rebeca Moreira et al.   BMC GENOMICS

Identification and functional analysis of a novel IFN-like protein (CgIFNLP) in Crassostrea gigas

(2015) Ran Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Cloning and characterization of a novel caspase-8-like gene in Crassostrea gigas

(2015) Chunyan Li et al.   FISH & SHELLFISH IMMUNOLOGY

Bioinformatics analysis to identify the differentially expressed genes of glaucoma

(2015) XIANG YAN et al.   Molecular Medicine Reports

Gene expression profile analysis of Manila clam (Ruditapes philippinarum) hemocytes after a Vibrio alginolyticus challenge using an immune-enriched oligo-microarray

(2014) Rebeca Moreira et al.   BMC GENOMICS

Transcriptional changes in Manila clam (Ruditapes philippinarum) in response to Brown Ring Disease

(2014) Bassem Allam et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular cloning and mRNA expression of the peptidoglycan recognition protein gene HcPGRP1 and its isoform HcPGRP1a from the freshwater mussel Hyriopsis cumingi

(2014) Ye Tao et al.   GENETICS AND MOLECULAR BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Activation of an innate immune response in the schistosome-transmitting snail Biomphalaria glabrata by specific bacterial PAMPs

(2013) John T. Sullivan et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Involvement of Pacific oyster CgPGRP-S1S in bacterial recognition, agglutination and granulocyte degranulation

(2013) Masao Iizuka et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The first evidence of positive selection in peptidoglycan recognition protein (PGRP) genes of Crassostrea gigas

(2013) Yang Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Experimental challenges of wild Manila clams with Perkinsus species isolated from naturally infected wild Manila clams

(2012) Tsukasa Waki et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

The oyster genome reveals stress adaptation and complexity of shell formation

(2012) Guofan Zhang et al.   NATURE

Massively Parallel RNA Sequencing Identifies a Complex Immune Gene Repertoire in the lophotrochozoan Mytilus edulis

(2012) Eva E. R. Philipp et al.   PLoS One

Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing

(2012) Rebeca Moreira et al.   PLoS One

Cloning and localization of MCdef, a defensin from Manila clams (Ruditapes philippinarum)

(2011) Mausumi Adhya et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Effect of crude lipopolysaccharide from Escherichia coli O127:B8 on the amebocyte-producing organ of Biomphalaria glabrata (Mollusca)

(2011) John T. Sullivan et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Gene expression analysis of clams Ruditapes philippinarum and Ruditapes decussatus following bacterial infection yields molecular insights into pathogen resistance and immunity

(2011) R. Moreira et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular cloning and mRNA expression of two peptidoglycan recognition protein (PGRP) genes from mollusk Solen grandis

(2011) Xiumei Wei et al.   FISH & SHELLFISH IMMUNOLOGY

Identification of two small heat shock proteins with different response profile to cadmium and pathogen stresses in Venerupis philippinarum

(2010) Chenghua Li et al.   CELL STRESS & CHAPERONES

MgC1q, a novel C1q-domain-containing protein involved in the immune response of Mytilus galloprovincialis

(2010) Camino Gestal et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular Characterization of a Novel Big Defensin from Clam Venerupis philippinarum

(2010) Jianmin Zhao et al.   PLoS One

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS

Expression of interferon and interferon-induced genes in salmonids in response to virus infection, interferon-inducing compounds and vaccination

(2008) Børre Robertsen   FISH & SHELLFISH IMMUNOLOGY

Characterization of the interferon genes in homozygous rainbow trout reveals two novel genes, alternate splicing and differential regulation of duplicated genes

(2008) Maureen K. Purcell et al.   FISH & SHELLFISH IMMUNOLOGY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences

(2008) Martina Proell et al.   PLoS One

Study of Diseases and the Immune System of Bivalves Using Molecular Biology and Genomics

(2008) Camino Gestal et al.   REVIEWS IN FISHERIES SCIENCE