Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness

Pricing of pharmaceuticals is becoming a major challenge for health systems

(2020) Steven G Morgan et al.   BMJ-British Medical Journal

Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2

(2019) Linh T. Nguyen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Safety and efficacy of cryopreserved autologous tumor infiltrating lymphocyte therapy (LN-144, lifileucel) in advanced metastatic melanoma patients who progressed on multiple prior therapies including anti-PD-1.

(2019) Amod Sarnaik et al.   JOURNAL OF CLINICAL ONCOLOGY

Severity-Adjusted Probability of Being Cost Effective

(2019) Matthijs M. Versteegh et al.   PHARMACOECONOMICS

Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

(2019) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adoptive cell transfer using autologous tumor infiltrating lymphocytes in gynecologic malignancies

(2018) Paul Mayor et al.   GYNECOLOGIC ONCOLOGY

Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma

(2018) John E. Mullinax et al.   Frontiers in Oncology

Early cost-effectiveness of tumor infiltrating lymphocytes (TIL) for second line treatment in advanced melanoma: a model-based economic evaluation

(2018) Valesca P. Retèl et al.   BMC CANCER

Advanced stage melanoma therapies: Detailing the present and exploring the future

(2018) Chelsea Luther et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option

(2018) Maartje W. Rohaan et al.   Journal for ImmunoTherapy of Cancer

Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer

(2017) Hee Jin Lee et al.   Oncotarget

Scenario drafting for early technology assessment of next generation sequencing in clinical oncology

(2016) S.E.P. Joosten et al.   BMC CANCER

Overcoming Challenges Facing Advanced Therapies in the EU Market

(2016) Mohamed Abou-El-Enein et al.   Cell Stem Cell

Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen

(2016) R. Andersen et al.   CLINICAL CANCER RESEARCH

A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma

(2016) Drew C. Deniger et al.   CLINICAL CANCER RESEARCH

Hurdles in clinical implementation of academic advanced therapy medicinal products: A national evaluation

(2016) Sofieke de Wilde et al.   CYTOTHERAPY

Actual costs of cancer drugs in 15 European countries

(2016) Wim H van Harten et al.   LANCET ONCOLOGY

About ATMPs, SOPs and GMP: The Hurdles to Produce Novel Skin Grafts for Clinical Use

(2016) Fabienne Hartmann-Fritsch et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma

(2015) V Baldan et al.   BRITISH JOURNAL OF CANCER

Are there specific translational challenges in regenerative medicine? Lessons from other fields

(2015) John Gardner et al.   Regenerative Medicine

Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma

(2015) Rikke Andersen et al.   Human Vaccines & Immunotherapeutics

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Regulating cell-based regenerative medicine: the challenges ahead

(2013) Robin R Ali et al.   Regenerative Medicine

Adoptive T-Cell Therapy Using Autologous Tumor-Infiltrating Lymphocytes for Metastatic Melanoma

(2012) Richard Wu et al.   CANCER JOURNAL

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

(2011) S. A. Rosenberg et al.   CLINICAL CANCER RESEARCH

Systematic Review of Medical Treatment in Melanoma: Current Status and Future Prospects

(2011) C. Garbe et al.   ONCOLOGIST

Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens

(2008) Mark E. Dudley et al.   JOURNAL OF CLINICAL ONCOLOGY

The NICE Cost-Effectiveness Threshold

(2008) Christopher McCabe et al.   PHARMACOECONOMICS