Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood during the COVID-19 pandemic

Optimizing Hydroxyurea Dosing in Sickle Cell Anemia: The Uganda MTD Study

(2020) Chandy C. John et al.   BLOOD

Initiating adjunct low-dose hydroxyurea therapy for stroke prevention in children with SCA during the COVID-19 pandemic

(2020) Michael R. DeBaun   BLOOD

American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults

(2020) M. R. DeBaun et al.   Blood Advances

Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia

(2019) Melanie E. Fields et al.   BLOOD

Robust Clinical and Laboratory Response to Hydroxyurea Using Pharmacokinetically Guided Dosing for Young Children with Sickle Cell Anemia

(2019) Patrick T. McGann et al.   AMERICAN JOURNAL OF HEMATOLOGY

RHgenotype matching for transfusion support in sickle cell disease

(2018) Stella T. Chou et al.   BLOOD

Long-term treatment follow-up of children with sickle cell disease monitored with abnormal transcranial Doppler velocities

(2016) F. Bernaudin et al.   BLOOD

Hydroxycarbamide treatment and brain MRI/MRA findings in children with sickle cell anaemia

(2016) Kerri A. Nottage et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia—TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

(2016) Russell E Ware et al.   LANCET

Secondary benefit of maintaining normal transcranial Doppler velocities when using hydroxyurea for prevention of severe sickle cell anemia

(2016) Djamila Labib Ghafuri et al.   PEDIATRIC BLOOD & CANCER

Prevention of conversion to abnormal transcranial Doppler with hydroxyurea in sickle cell anemia: A Phase III international randomized clinical trial

(2015) Jane S. Hankins et al.   AMERICAN JOURNAL OF HEMATOLOGY

Hydroxyurea lowers transcranial Doppler flow velocities in children with sickle cell anaemia in a Nigerian cohort

(2015) IkeOluwa Lagunju et al.   PEDIATRIC BLOOD & CANCER

Stroke With Transfusions Changing to Hydroxyurea (SWiTCH)

(2012) R. E. Ware et al.   BLOOD

Combined blood transfusion and hydroxycarbamide in children with sickle cell anaemia

(2012) Valentine Brousse et al.   BRITISH JOURNAL OF HAEMATOLOGY

Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease

(2010) M. L. Hulbert et al.   BLOOD