Synthesis, biological evaluation and modeling of hybrids from tetrahydro-1H-pyrazolo[3,4-b]quinolines as dual cholinestrase and COX-2 inhibitors

Title
Synthesis, biological evaluation and modeling of hybrids from tetrahydro-1H-pyrazolo[3,4-b]quinolines as dual cholinestrase and COX-2 inhibitors
Authors
Keywords
Alzheimer's disease, Anti-cholinesterase activity, COX-2 inhibition, Tetrahydro-1, H, -pyrazolo[3,4-, b, ]quinolines, Hepatotoxicity
Journal
BIOORGANIC CHEMISTRY
Volume 100, Issue -, Pages 103895
Publisher
Elsevier BV
Online
2020-05-04
DOI
10.1016/j.bioorg.2020.103895

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