Design, synthesis and biological activity evaluation of novel 4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl) oxy) pyridine-2-yl) amino derivatives as potent transforming growth factor-β (TGF-β) type I receptor inhibitors

Published 2020 View Full Article

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Title
Design, synthesis and biological activity evaluation of novel 4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl) oxy) pyridine-2-yl) amino derivatives as potent transforming growth factor-β (TGF-β) type I receptor inhibitors
Authors
Keywords
TGF-β type I receptor, ALK5 inhibitors, Inhibitory activity
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 30, Issue 16, Pages 127339
Publisher
Elsevier BV
Online
2020-06-10
DOI
10.1016/j.bmcl.2020.127339

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