Antiplatelet Effect of Carbon Monoxide Is Mediated by NAD + and ATP Depletion

Mass Spectrometry-based Label-free Quantitative Proteomics To Study the Effect of 3PO Drug at Cellular Level

(2019) Sarath Babu Nukala et al.   ACS Medicinal Chemistry Letters

The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion

(2019) Willem Delabie et al.   TRANSFUSION

Critical Roles of Carbon Monoxide and Nitric Oxide in Ca2+ Signaling for Insulin Secretion in Pancreatic Islets

(2018) Faiz Ur Rahman et al.   ANTIOXIDANTS & REDOX SIGNALING

CORM-401 induces calcium signalling, NO increase and activation of pentose phosphate pathway in endothelial cells

(2018) Patrycja Kaczara et al.   FEBS Journal

The effects of aspirin and ticagrelor on Toll-like receptor (TLR)-mediated platelet activation: results of a randomized, cross-over trial

(2018) Kathryn E Hally et al.   PLATELETS

Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus

(2017) Jayne Louise Wilson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular and angiogenic activities of CORM-401, an oxidant-sensitive CO-releasing molecule

(2016) Sarah Fayad-Kobeissi et al.   BIOCHEMICAL PHARMACOLOGY

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Carbon monoxide shifts energetic metabolism from glycolysis to oxidative phosphorylation in endothelial cells

(2016) Patrycja Kaczara et al.   FEBS LETTERS

Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels

(2015) Patrycja Kaczara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Metabolic Plasticity in Resting and Thrombin Activated Platelets

(2015) Saranya Ravi et al.   PLoS One

Platelets from Asthmatic Individuals Show Less Reliance on Glycolysis

(2015) Weiling Xu et al.   PLoS One

Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation

(2014) N. Cardenes et al.   BLOOD

Epithelial sodium channel modulates platelet collagen activation

(2014) Doris Cerecedo et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway

(2014) Takehiro Yamamoto et al.   Nature Communications

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

CORM-3, a water soluble CO-releasing molecule, uncouples mitochondrial respiration via interaction with the phosphate carrier

(2013) Romain Long et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Suppressive Effect of CORM-2 on LPS-Induced Platelet Activation by Glycoprotein Mediated HS1 Phosphorylation Interference

(2013) Dadong Liu et al.   PLoS One

Antithrombotic Properties of Water-Soluble Carbon Monoxide-Releasing Molecules

(2012) Karol Kramkowski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heme Binding Properties of Glyceraldehyde-3-phosphate Dehydrogenase

(2012) Luciana Hannibal et al.   BIOCHEMISTRY

Protective effect of heme oxygenase-1 on hepatic ischemia-reperfusion injury through inhibition of platelet adhesion to the sinusoids

(2012) Takafumi Tamura et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inhibition of platelet aggregation by carbon monoxide-releasing molecules (CO-RMs): comparison with NO donors

(2012) Stefan Chlopicki et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Endothelial Cell and Platelet Bioenergetics: Effect of Glucose and Nutrient Composition

(2012) Brian D. Fink et al.   PLoS One

Effects of carbon monoxide (CO) delivery by a CO donor or hemoglobin on vascular hypoxia inducible factor 1α and mitochondrial respiration

(2012) Chad E.N. Reiter et al.   FEBS Open Bio

Carbon monoxide prevents hepatic mitochondrial membrane permeabilization

(2011) Cláudia SF Queiroga et al.   BMC CELL BIOLOGY

A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species

(2011) Luisa Lo Iacono et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Carbon Monoxide Rescues Heme Oxygenase-1-Deficient Mice from Arterial Thrombosis in Allogeneic Aortic Transplantation

(2009) Bo Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

CD38 as a Regulator of Cellular NAD: A Novel Potential Pharmacological Target for Metabolic Conditions

(2009) Eduardo Chini   CURRENT PHARMACEUTICAL DESIGN

Platelets of type 2 diabetic patients are characterized by high ATP content and low mitochondrial membrane potential

(2009) Jianmin Ran et al.   PLATELETS

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

(2008) Chris E. Cooper et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES