Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity

Published 2020 View Full Article

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Title
Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
Authors
Keywords
Antiviral, Herpes simplex virus, siRNA, Innate immunity, Fluoro-modification, Bacteriophage phi6 RNA-dependent RNA polymerase
Journal
ANTIVIRAL RESEARCH
Volume -, Issue -, Pages 104916
Publisher
Elsevier BV
Online
2020-08-13
DOI
10.1016/j.antiviral.2020.104916

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