Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle

6′-β-Fluoro-homoaristeromycin and 6′-fluoro-homoneplanocin A are potent inhibitors of chikungunya virus replication through their direct effect on the viral non-structural protein 1

(2020) Kristina Kovacikova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

(2020) Victor M Corman et al.   Eurosurveillance

Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle

(2020) Hongzhou Lu et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

(2020) Barry Rockx et al.   SCIENCE

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

(2020) Timothy P. Sheahan et al.   Science Translational Medicine

Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

(2020) Irina C. Albulescu et al.   Viruses-Basel

Clinical and virological data of the first cases of COVID-19 in Europe: a case series

(2020) Francois-Xavier Lescure et al.   LANCET INFECTIOUS DISEASES

No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection

(2020) J.M. Molina et al.   MEDECINE ET MALADIES INFECTIEUSES

TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms

(2019) Jasmijn A. Schrumpf et al.   Journal of Innate Immunity

Airway and alveolar epithelial cells in culture

(2019) Pieter S. Hiemstra et al.   EUROPEAN RESPIRATORY JOURNAL

100 Years of Suramin

(2019) Natalie Wiedemar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence

(2018) Gimano D. Amatngalim et al.   EUROPEAN RESPIRATORY JOURNAL

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

(2017) Timothy P. Sheahan et al.   Science Translational Medicine

Suramin interacts with the positively charged region surrounding the 5-fold axis of the EV-A71 capsid and inhibits multiple enterovirus A

(2017) Peijun Ren et al.   Scientific Reports

Suramin inhibits chikungunya virus replication through multiple mechanisms

(2015) Irina C. Albulescu et al.   ANTIVIRAL RESEARCH

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

(2015) Vineet D Menachery et al.   NATURE MEDICINE

Suramin Inhibits Chikungunya Virus Entry and Transmission

(2015) Yi-Jung Ho et al.   PLoS One

Suramin inhibits helicase activity of NS3 protein of dengue virus in a fluorescence-based high throughput assay format

(2014) Chandrakala Basavannacharya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of Synthetic Chikungunya Viruses Based on the Consensus Sequence of Recent E1-226V Isolates

(2013) Florine E. M. Scholte et al.   PLoS One

Dynamic Innate Immune Responses of Human Bronchial Epithelial Cells to Severe Acute Respiratory Syndrome-Associated Coronavirus Infection

(2010) Tomoki Yoshikawa et al.   PLoS One