Treatment Considerations for CNS Infections Caused by Vancomycin-Resistant Enterococcus faecium: A Focused Review of Linezolid and Daptomycin

High rate of linezolid intermediate susceptibility and resistance among enteric vancomycin-resistant Enterococcus (VRE) recovered from hospitalized patients actively screened for VRE colonization

(2019) Thomas J. Dilworth et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017

(2019) Lindsey M. Weiner-Lastinger et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice

(2019) Gauri G Rao et al.   THERAPEUTIC DRUG MONITORING

Incidence and Risk Factors for Development of Thrombocytopenia in Patients Treated With Linezolid for 7 Days or Greater

(2018) Alyssa D. Rabon et al.   ANNALS OF PHARMACOTHERAPY

Risk factors for linezolid-induced thrombocytopenia in patients without haemato-oncologic diseases

(2018) Go Wun Choi et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Influence of Minimum Inhibitory Concentration in Clinical Outcomes ofEnterococcus faeciumBacteremia Treated With Daptomycin: Is it Time to Change the Breakpoint?

(2016) Bhavarth S. Shukla et al.   CLINICAL INFECTIOUS DISEASES

Daptomycin versus linezolid for the treatment of vancomycin-resistant enterococcal bacteraemia: implications of daptomycin dose

(2016) Y.-C. Chuang et al.   CLINICAL MICROBIOLOGY AND INFECTION

A retrospective study of the risk factors for linezolid-induced thrombocytopenia and anemia

(2016) Yuki Hanai et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Comparison of Linezolid and Vancomycin for Methicillin-ResistantStaphylococcus aureusPneumonia: Institutional Implications

(2016) ManShan C. Tong et al.   PHARMACOTHERAPY

Evaluation of Effectiveness and Safety of High-Dose Daptomycin: Results from Patients Included in the European Cubicin® Outcomes Registry and Experience

(2015) R. Andrew Seaton et al.   ADVANCES IN THERAPY

In VitroActivity of Daptomycin in Combination with β-Lactams, Gentamicin, Rifampin, and Tigecycline against Daptomycin-Nonsusceptible Enterococci

(2015) Janet A. Hindler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Examining the Use of Ceftaroline in the Treatment of Streptococcus pneumoniae Meningitis with Reference to Human Cathelicidin LL-37

(2015) George Sakoulas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Editorial Commentary: Linezolid vs Daptomycin for Vancomycin-Resistant Enterococci: The Evidence Gap Between Trials and Clinical Experience

(2015) James A. McKinnell et al.   CLINICAL INFECTIOUS DISEASES

 -Lactam combinations with daptomycin provide synergy against vancomycin-resistant Enterococcus faecalis and Enterococcus faecium

(2015) J. R. Smith et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of Daptomycin or Linezolid in Combination with Rifampin or Gentamicin against Biofilm-Forming Enterococcus faecalis or E. faecium in anIn VitroPharmacodynamic Model Using Simulated Endocardial Vegetations and anIn VivoSurvival Assay Using Galleria mellonella Larvae

(2014) Megan K. Luther et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

(2014) Lauren M. Boak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

(2014) S. Luque et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Central nervous system infections due to vancomycin-resistant enterococci: case series and review of the literature

(2014) Jeffrey S. Wang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Successful use of ceftaroline for the treatment of MRSA meningitis secondary to an infectious complication of lumbar spine surgery

(2014) M. A. Balouch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of the novel combination of daptomycin plus ceftriaxone against vancomycin-resistant enterococci in an in vitro pharmacokinetic/pharmacodynamic simulated endocardial vegetation model

(2014) A. Hall Snyder et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative Effectiveness of Linezolid and Vancomycin Among a National Veterans Affairs Cohort with Methicillin-ResistantStaphylococcus aureusPneumonia

(2014) Aisling R. Caffrey et al.   PHARMACOTHERAPY

Assessment of the in vitro synergy of daptomycin plus linezolid against multidrug-resistant enterococci

(2014) José M. Entenza et al.   Journal of Global Antimicrobial Resistance

Multicenter Study of High-Dose Daptomycin for Treatment of Enterococcal Infections

(2013) Anthony M. Casapao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ceftaroline Restores Daptomycin Activity against Daptomycin-Nonsusceptible Vancomycin-Resistant Enterococcus faecium

(2013) George Sakoulas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intraventricular Daptomycin and Intravenous Linezolid for the Treatment of External Ventricular-Drain–Associated Ventriculitis Due to Vancomycin-Resistant Enterococcus faecium

(2012) Scott W Mueller et al.   ANNALS OF PHARMACOTHERAPY

Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study

(2012) R. G. Wunderink et al.   CLINICAL INFECTIOUS DISEASES

Therapeutic drug monitoring may improve safety outcomes of long-term treatment with linezolid in adult patients

(2012) F. Pea et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Vancomycin-resistant Enterococcus faecium meningitis in adults: Case series and review of the literature

(2012) Bettina M. Knoll et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Vancomycin-resistant enterococcal meningitis in an autologous stem cell transplant recipient cured with linezolid

(2012) K.L. Frasca et al.   Transplant Infectious Disease

Intrinsic and acquired resistance mechanisms in enterococcus

(2012) Brian L. Hollenbeck et al.   Virulence

Pharmacokinetics of Single-Dose Daptomycin in Patients with Suspected or Confirmed Neurological Infections

(2011) Ravina Kullar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ampicillin Enhances Daptomycin- and Cationic Host Defense Peptide-Mediated Killing of Ampicillin- and Vancomycin-Resistant Enterococcus faecium

(2011) George Sakoulas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Vancomycin-resistant Enterococcus faecium Meningitis Successfully Treated with Linezolid

(2011) Kelly N. Mizell et al.   SOUTHERN MEDICAL JOURNAL

Treatment of Meningitis Caused by Vancomycin-Resistant Enterococcus faecium: High-Dose and Combination Daptomycin Therapy

(2010) Jennifer Le et al.   ANNALS OF PHARMACOTHERAPY

The importance of tissue penetration in achieving successful antimicrobial treatment of nosocomial pneumonia and complicated skin and soft-tissue infections caused by methicillin-resistantStaphylococcus aureus: vancomycin and linezolid

(2010) Gary E. Stein et al.   CURRENT MEDICAL RESEARCH AND OPINION

Pharmacokinetic/pharmacodynamic (PK/PD) considerations in the management of Gram-positive bacteraemia

(2010) Francesco Scaglione   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Successful Treatment of Methicillin‐ResistantStaphylococcus aureusMeningitis with Daptomycin

(2008) Dong Heun Lee et al.   CLINICAL INFECTIOUS DISEASES