Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity

Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity

(2020) Yasuhiro Onogi et al.   Scientific Reports

Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice

(2020) Akari Ishikawa et al.   PLoS One

Clinical Use of DPP-4 Inhibitors

(2019) Baptist Gallwitz   Frontiers in Endocrinology

Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding

(2019) Martin Gustavsson et al.   Science Signaling

Role of VEGFs in metabolic disorders

(2019) M. di Somma et al.   ANGIOGENESIS

Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology

(2018) K.E. Quinn et al.   CYTOKINE

SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes

(2018) Jihoon Shin et al.   DIABETES

Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition

(2018) Elodie M. Varin et al.   Cell Metabolism

Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance

(2017) Tsutomu Wada et al.   JOURNAL OF ENDOCRINOLOGY

HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance

(2016) Akiko Takikawa et al.   DIABETES

DPP-4 Inhibition by Linagliptin Attenuates Obesity-Related Inflammation and Insulin Resistance by Regulating M1/M2 Macrophage Polarization

(2016) Fen Zhuge et al.   DIABETES

DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation

(2015) Takanori Shinjo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CXCL12-CXCR7 axis is important for tumor endothelial cell angiogenic property

(2015) Kenji Yamada et al.   INTERNATIONAL JOURNAL OF CANCER

Adipokines in health and disease

(2015) Mathias Fasshauer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dipeptidyl Peptidase-4 Regulation of SDF-1/CXCR4 Axis: Implications for Cardiovascular Disease

(2015) Jixin Zhong et al.   Frontiers in Immunology

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

(2014) Yun Sok Lee et al.   CELL

Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl Peptidase-4 Inhibitors

(2014) Erin E. Mulvihill et al.   ENDOCRINE REVIEWS

Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity

(2014) Longbiao Yao et al.   FASEB JOURNAL

Adipose Vascular Endothelial Growth Factor Regulates Metabolic Homeostasis through Angiogenesis

(2013) Hoon-Ki Sung et al.   Cell Metabolism

Adipose Dipeptidyl Peptidase-4 and Obesity: Correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

(2013) H. Sell et al.   DIABETES CARE

Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice

(2013) S. Fujisaka et al.   DIABETOLOGIA

Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet

(2012) Rika Yonezawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12

(2012) Anup Kumar Singh et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CXCR7 impact on CXCL12 biology and disease

(2012) Lorena Sánchez-Martín et al.   TRENDS IN MOLECULAR MEDICINE

The Differential Role of Hif1β/Arnt and the Hypoxic Response in Adipose Function, Fibrosis, and Inflammation

(2011) Kevin Y. Lee et al.   Cell Metabolism

Dipeptidyl Peptidase 4 Is a Novel Adipokine Potentially Linking Obesity to the Metabolic Syndrome

(2011) D. Lamers et al.   DIABETES

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

(2010) Yihai Cao   NATURE REVIEWS DRUG DISCOVERY

Hypoxia-Inducible Factor 1  Induces Fibrosis and Insulin Resistance in White Adipose Tissue

(2009) N. Halberg et al.   MOLECULAR AND CELLULAR BIOLOGY