Tead1 is essential for mitochondrial function in cardiomyocytes

VGLL4 plays a critical role in heart valve development and homeostasis

(2019) Wei Yu et al.   PLoS Genetics

Virtual screening-guided discovery of thioredoxin reductase inhibitors

(2019) Ruijuan Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers

(2019) Brynn N. Akerberg et al.   Nature Communications

YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α

(2018) Akiko Mammoto et al.   MICROVASCULAR RESEARCH

Mitochondrial dysfunction in pathophysiology of heart failure

(2018) Bo Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor

(2018) Yuxuan Guo et al.   Nature Communications

Loss of cardiac carnitine palmitoyltransferase 2 results in rapamycin-resistant, acetylation-independent hypertrophy

(2017) Andrea S. Pereyra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the Hippo Pathway Transcription Factor TEAD

(2017) Kimberly C. Lin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure

(2016) Dale J. Hamilton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association

(2016) Biykem Bozkurt et al.   CIRCULATION

Insulin Signaling and Heart Failure

(2016) Christian Riehle et al.   CIRCULATION RESEARCH

Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth

(2016) Zhiqiang Lin et al.   DEVELOPMENTAL CELL

Mitochondrial function as a therapeutic target in heart failure

(2016) David A. Brown et al.   Nature Reviews Cardiology

Epidemiology of Heart Failure and Scope of the Problem

(2013) Longjian Liu et al.   CARDIOLOGY CLINICS

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

Cardiac Metabolism in Heart Failure

(2013) Torsten Doenst et al.   CIRCULATION RESEARCH

Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes

(2013) Stephen C. Kolwicz et al.   CIRCULATION RESEARCH

Dilated cardiomyopathy: the complexity of a diverse genetic architecture

(2013) Ray E. Hershberger et al.   Nature Reviews Cardiology

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

(2013) Tobias A. Beyer et al.   Cell Reports

Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy

(2012) Andrew M. Walters et al.   CIRCULATION RESEARCH

Mitochondrial dysfunction in heart failure

(2012) Mariana G. Rosca et al.   HEART FAILURE REVIEWS

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

(2008) M. Ota et al.   DEVELOPMENT

Redundant Roles of Tead1 and Tead2 in Notochord Development and the Regulation of Cell Proliferation and Survival

(2008) A. Sawada et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

MCAT Elements and the TEF-1 Family of Transcription Factors in Muscle Development and Disease

(2007) Tadashi Yoshida   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY