Mitochondrial oxidative injury: A key player in nonalcoholic fatty liver disease

Role and Mechanisms of Mitophagy in Liver Diseases

(2020) Xiaowen Ma et al.   Cells

Autophagy in hepatic adaptation to stress

(2019) Younis Hazari et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation

(2018) Samar H Ibrahim et al.   GUT

Determinants of fibrosis progression and regression in NASH

(2018) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice

(2017) Abudukadier Abulizi et al.   FASEB JOURNAL

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity

(2015) Sini Heinonen et al.   DIABETES

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

(2015) Santhosh Satapati et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitohormesis

(2014) Jeanho Yun et al.   Cell Metabolism

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis

(2014) Jef Verbeek et al.   GUT

Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications

(2014) Byoung-Joon Song et al.   Redox Biology

Convergent pathways that cause hepatic fibrosis in NASH

(2013) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

(2013) Kari T. Chambers et al.   Molecular Metabolism

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

The Genetic Epidemiology of Nonalcoholic Fatty Liver Disease

(2012) Silvia Sookoian et al.   Clinics in Liver Disease

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis

(2012) Claudia von Montfort et al.   JOURNAL OF HEPATOLOGY

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

(2011) Haihong Zong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipokines and Redox Signaling: Impact on Fatty Liver Disease

(2011) Maurizio Parola et al.   ANTIOXIDANTS & REDOX SIGNALING

Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice

(2011) Michal Aharoni-Simon et al.   LABORATORY INVESTIGATION

DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation

(2010) Suneil K. Koliwad et al.   JOURNAL OF CLINICAL INVESTIGATION

Uncoupling proteins and non-alcoholic fatty liver disease

(2009) Helena Cortez-Pinto et al.   JOURNAL OF HEPATOLOGY

Vitamin E Succinate Enhances Steatotic Liver Energy Status and Prevents Oxidative Damage Following Ischemia/Reperfusion

(2009) Z.P. Evans et al.   TRANSPLANTATION PROCEEDINGS

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Alterations of hepatic ATP homeostasis and respiratory chain during development of non-alcoholic steatohepatitis in a rodent model

(2008) G. Serviddio et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

(2008) Sudheer K. Mantena et al.   FREE RADICAL BIOLOGY AND MEDICINE

Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury

(2008) G Serviddio et al.   GUT

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET