Review
Chemistry, Physical
Robin Augustine, Abdulla Al Mamun, Anwarul Hasan, Shaheen Abdul Salam, Ramya Chandrasekaran, Rashid Ahmed, Avnesh S. Thakor
Summary: The application of nanostructured materials in medicine, particularly in cancer diagnosis, shows great promise in aiding early detection, treatment, and patient follow-up. The tunable physical, chemical, and biological properties of nanomaterials make them highly desirable for diagnosing and treating various diseases, including cancers.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Mike Filius, Sung Hyun Kim, Ivo Severins, Chirlmin Joo
Summary: The research team introduced a new method that allows for determining multiple distances between FRET pairs in a single object by resolving the FRET efficiency of multiple fluorophore pairs through transient binding of short DNA strands. This FRET X technology is expected to be a tool for high-resolution analysis of biomolecules and nanostructures.
Article
Multidisciplinary Sciences
Artem N. Abramov, Igor Y. Chestnov, Ekaterina S. Alimova, Tatiana Ivanova, Ivan S. Mukhin, Dmitry N. Krizhanovskii, Ivan A. Shelykh, Ivan V. Iorsh, Vasily Kravtsov
Summary: By using local deformation of monolayer WSe2, we have successfully created high-purity single-photon emitters. Through nanoindentation and atomic force microscopy, we have identified the single-photon emitting sites and reconstructed the details of the surrounding local strain potential. The experimental results suggest that the single-photon emission is likely due to strain-induced spectral shift of dark excitonic states and their hybridization with localized states of individual defects.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Nesrine Aissaoui, Josephine Lai-Kee-Him, Allan Mills, Nathalie Declerck, Zakia Morichaud, Konstantin Brodolin, Sonia Baconnais, Eric Le Cam, Jean Baptiste Charbonnier, Remy Sounier, Sebastien Granier, Virginie Ropars, Patrick Bron, Gaetan Bellot
Summary: Technological breakthroughs in electron microscopy have made it possible to study biological macromolecular complexes with novel challenges, such as sample preparation and heterogeneous macromolecular assemblies. In this study, a V-shaped DNA origami template was used to position proteins, demonstrating a new approach for characterizing mechanosensitive proteins and expanding the range of potential targets for single-particle EM investigation. Validation with RNAP protein showed compatibility with cryo-EM sample preparation.
Article
Chemistry, Multidisciplinary
Junlin Sun, Feng Liu, Wenqian Yu, Dandan Fu, Qunying Jiang, Fengye Mo, Xiuyuan Wang, Tianhui Shi, Fuan Wang, Dai-Wen Pang, Xiaoqing Liu
Summary: Quantum dot nanomaterials can monitor vaccine dynamics, enhance immune response, and enable spatial and temporal tracking of vaccine transportation, providing a powerful strategy for studying immune response and evaluating vaccine efficacy.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Spectroscopy
Jinzhi Lv, Shuying Liu, Yanming Miao
Summary: A fluorescent biological quantum dots (Bio-dots) probe was prepared using TC base-rich single-stranded DNA (ssDNA) as raw material, with an extended lifetime and low detection limit for melamine detection. The probe is considered a green and environmentally-friendly photoluminescent functional material due to the non-toxic nature of the raw material and absence of toxic substances in the synthesis process.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Subir Paul, Anindita Bhattacharya, Niladri Hazra, Kousik Gayen, Prosenjit Sen, Arindam Banerjee
Summary: This study demonstrates the one-step preparation of lipophilic carbon dots and their usage in selectively imaging lipid droplets. This provides a new approach for studying lipid droplets inside living cells.
Article
Chemistry, Applied
Qingyi Wei, Peiyao Zhang, Ting Liu, Hongbin Pu, Da-Wen Sun
Summary: A simple fluorescent biosensor based on single-stranded DNA (ssDNA) and carbon quantum dots (CQDs) was developed for the sensitive detection of acrylamide (AM) in food products. The sensor exhibited a low detection limit of 2.41 x 10-8 M in standard solution and a wide linear range with high accuracy. Practical applications of the biosensor showed promising results with good recovery percentage in bread crust samples.
Article
Biophysics
Shuyan Xu, Tingfan Wu, Na Ren, Jingwen Li, Yuying Zhang, Haiqing Wang, Hong Liu, Haiyun Liu
Summary: A study has developed an integrated DNA triangular prism nanomachines for dynamic recognition and imaging of biomarkers from the plasma membrane to the cytoplasm. This strategy provides a reliable platform for tumor diagnosis and biomarker research.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Shuyan Xu, Tingfan Wu, Na Ren, Jingwen Li, Yuying Zhang, Haiqing Wang, Hong Liu, Haiyun Liu
Summary: This study presents an integrated DNA nanomachine that enables the identification and dynamic response of biomarkers from the plasma membrane to the cytoplasm in living cells. This platform offers a reliable tool for tumor diagnosis and biomarker research.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Shuai Li, Feng Li, Yuhang Dong, Nachuan Song, Li Pan, Dayong Yang
Summary: Carbon dots synthesized from ribonucleosides can mimic artificial enzymes and regulate the structure and oxidative cleavage of DNA.
Article
Biochemistry & Molecular Biology
Brandon Davis, Peng Shi, Erin Gaddes, Jinping Lai, Yong Wang
Summary: This study investigated the reversible display of supramolecular nanomaterials on the surface of living cells. The data showed that DNA initiators could induce the self-assembly of DNA-alginate conjugates to form supramolecular nanomaterials and amplify the fluorescence signals on the cell surface. Complementary DNA (cDNA), DNase, and alginase could all trigger the reversal of the signals from the cell surface.
Article
Materials Science, Multidisciplinary
Yanbin Zhang, Lu-Lu Qiao, Zhi-Qiang Zhang, Yong-Fang Liu, Lin-Song Li, Huaibin Shen, Mei-Xia Zhao
Summary: Mitochondria play a crucial role in numerous cellular functions, making it important to conduct long-term stable studies of their activity. However, current commercial mitochondrial probes have poor stability, hindering their ability to trace mitochondria. In this study, a novel mitochondrial fluorescent probe was designed using InP quantum dots as a fluorescent marker, combined with TPP for specific recognition. The bespoke InP quantum dots probes demonstrated several advantages, including simple and low-cost synthesis, high quantum yields, extremely low toxicity, good biocompatibility, and excellent photochemical stability.
MATERIALS & DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Xiaowei Yu, Kaikai Liu, Bolun Wang, Hongyue Zhang, Yuanyuan Qi, Jihong Yu
Summary: This study successfully developed a time-dependent polychrome stereoscopic luminescence system by designing a luminescence system with adjustable afterglow lifetime and multicolor quantum dots. The system allows tunable afterglow emission and has been applied in time-space division multiplexing, expanding the information capacity.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Analytical
Shengnan Fu, Tengfang Zhang, Huanling Jiang, Yan Xu, Jing Chen, Linghao Zhang, Xin Su
Summary: Single-molecule tools, with the application of DNA nanotechnology, not only improve sensitivity and specificity, but also provide molecular receptors and rulers, helping to address the challenges hindering the development of single-molecule sensing and imaging.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Materials Science, Biomaterials
Tian Tian, Yan Han, Bing Ma, Chengtie Wu, Jiang Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2015)
Article
Materials Science, Biomaterials
Qiongyu Zeng, Yan Han, Haiyan Li, Jiang Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2015)
Article
Materials Science, Biomaterials
Yan Han, Yonghui Li, Qiongyu Zeng, Haiyan Li, Jinliang Peng, Yuhong Xu, Jiang Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2017)
Article
Engineering, Biomedical
Yanling Zhou, Long Gao, Jinliang Peng, Min Xing, Yan Han, Xiaoya Wang, Yuhong Xu, Jiang Chang
ADVANCED HEALTHCARE MATERIALS
(2018)
Article
Engineering, Biomedical
Yan Han, Qiongyu Zeng, Haiyan Li, Jiang Chang
ACTA BIOMATERIALIA
(2013)
Article
Engineering, Biomedical
Qiongyu Zeng, Yan Han, Haiyan Li, Jiang Chang
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2014)
Article
Biochemistry & Molecular Biology
Rui Hua, Qingwen Ni, Travis D. Eliason, Yan Han, Sumin Gu, Daniel P. Nicolella, Xiaodu Wang, Jean X. Jiang
Article
Engineering, Biomedical
Pengfei Zhao, Yan Han, Holly Nguyen, Eva Corey, Xiaohu Gao
Summary: A simple yet effective cancer treatment method involves repurposing clinically approved magnetic nanoparticles and utilizing static parallel magnetic fields for intracellular nanoparticle self-assembly, leading to targeted cell death while preserving other cells and organs intact. This approach opens up a new avenue for cancer treatment by utilizing nanosciences and nanoparticle design principles accumulated over the past decades.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Yan Han, Joel Gomez, Rui Hua, Pengwei Xiao, Wei Gao, Jean X. Jiang, Xiaodu Wang
Summary: Research shows that removal of GAGs from bone tissues increases the elastic modulus and reduces plastic energy dissipation, particularly in wet conditions. GAGs not only affect the capacity of EFM, but may also impact the elastic modulus of MCFs.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Endocrinology & Metabolism
Pengwei Xiao, Tinghe Zhang, Xuanliang Neil Dong, Yan Han, Yufei Huang, Xiaodu Wang
Article
Nanoscience & Nanotechnology
Yonghui Li, Yan Han, Xiaoya Wang, Jinliang Peng, Yuhong Xu, Jiang Chang
ACS APPLIED MATERIALS & INTERFACES
(2017)
Article
Chemistry, Multidisciplinary
Xiaoya Wang, Long Gao, Yan Han, Min Xing, Cancan Zhao, Jinliang Peng, Jiang Chang
