Ionic Liquids and Deep Eutectic Solvents for Enhanced Delivery of Antibodies in the Gastrointestinal Tract

Biomimetic Micromotor Enables Active Delivery of Antigens for Oral Vaccination

(2019) Xiaoli Wei et al.   NANO LETTERS

Design Principles of Ionic Liquids for Transdermal Drug Delivery

(2019) Eden E. L. Tanner et al.   ADVANCED MATERIALS

Development of pH-responsive organic-inorganic hybrid nanocomposites as an effective oral delivery system of protein drugs

(2019) Sang Hoon Lee et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced paracellular delivery of vaccine by hydrogel microparticles-mediated reversible tight junction opening for effective oral immunization

(2019) Xiang Yi Chen et al.   JOURNAL OF CONTROLLED RELEASE

Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability

(2019) Nicholas G. Lamson et al.   Nature Biomedical Engineering

Advances in oral peptide therapeutics

(2019) Daniel J. Drucker   NATURE REVIEWS DRUG DISCOVERY

Materials for oral delivery of proteins and peptides

(2019) Tyler D. Brown et al.   Nature Reviews Materials

Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery

(2018) Weiwei Fan et al.   BIOMATERIALS

Recent advances in oral delivery of biologics: nanomedicine and physical modes of delivery

(2018) Driton Vllasaliu et al.   Expert Opinion on Drug Delivery

Overview of Antibody Drug Delivery

(2018) Sahar Awwad et al.   Pharmaceutics

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

(2018) J. Scott Crowe et al.   Scientific Reports

Local delivery of macromolecules to treat diseases associated with the colon

(2018) A. Bak et al.   ADVANCED DRUG DELIVERY REVIEWS

Oral delivery of the anti-tumor necrosis factor α domain antibody, V565, results in high intestinal and fecal concentrations with minimal systemic exposure in cynomolgus monkeys

(2018) J. Scott Crowe et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Non-invasive delivery strategies for biologics

(2018) Aaron C. Anselmo et al.   NATURE REVIEWS DRUG DISCOVERY

Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist

(2018) Stephen T. Buckley et al.   Science Translational Medicine

Choline based ionic liquids and their applications in organic transformation

(2017) Balu L. Gadilohar et al.   JOURNAL OF MOLECULAR LIQUIDS

Micromotor-enabled active drug delivery for in vivo treatment of stomach infection

(2017) Berta Esteban-Fernández de Ávila et al.   Nature Communications

The intestinal barrier: a fundamental role in health and disease

(2017) Maaike Vancamelbeke et al.   Expert Review of Gastroenterology & Hepatology

Current progress in innovative engineered antibodies

(2017) William R. Strohl   Protein & Cell

A new approach to quantification of mAb aggregates using peptide affinity probes

(2017) Crystal S. F. Cheung et al.   Scientific Reports

Oral delivery of macromolecular drugs: Where we are after almost 100 years of attempts

(2016) Elena Moroz et al.   ADVANCED DRUG DELIVERY REVIEWS

Sodium alginate decreases the permeability of intestinal mucus

(2016) Alan R. Mackie et al.   FOOD HYDROCOLLOIDS

AVX-470, an Orally Delivered Anti-Tumour Necrosis Factor Antibody for Treatment of Active Ulcerative Colitis: Results of a First-in-Human Trial

(2016) M. Scott Harris et al.   Journal of Crohns & Colitis

A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives

(2016) Abdul Muheem et al.   SAUDI PHARMACEUTICAL JOURNAL

Choline and Geranate Deep Eutectic Solvent as a Broad-Spectrum Antiseptic Agent for Preventive and Therapeutic Applications

(2016) Michael Zakrewsky et al.   Advanced Healthcare Materials

Inhibited fragmentation of mAbs in buffered ionic liquids

(2015) Romiza R. Mazid et al.   CHEMICAL COMMUNICATIONS

Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Antibodies: An in Vitro and ex Vivo Evaluation of Antibody Stability and Bioactivity

(2015) Brenda R. Carrillo-Conde et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Safety and Efficacy of Oral Octreotide in Acromegaly: Results of a Multicenter Phase III Trial

(2015) Shlomo Melmed et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Microneedles for Drug Delivery via the Gastrointestinal Tract

(2015) Giovanni Traverso et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Circular Dichroism Spectroscopy as a Tool for Monitoring Aggregation in Monoclonal Antibody Therapeutics

(2014) Varsha Joshi et al.   ANALYTICAL CHEMISTRY

Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

(2014) Marie Boegh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Ionic Liquids in Pharmaceutical Applications

(2014) I.M. Marrucho et al.   Annual Review of Chemical and Biomolecular Engineering

Permeation of Insulin, Calcitonin and Exenatide across Caco-2 Monolayers: Measurement Using a Rapid, 3-Day System

(2013) Vivek Gupta et al.   PLoS One

Glucose-Reducing Effect of the ORMD-0801 Oral Insulin Preparation in Patients with Uncontrolled Type 1 Diabetes: A Pilot Study

(2013) Roy Eldor et al.   PLoS One

Oral delivery of octreotide acetate in Intravail® improves uptake, half-life, and bioavailability over subcutaneous administration in male Swiss Webster mice

(2011) Edward T. Maggio et al.   REGULATORY PEPTIDES

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

(2010) Ron J. Keizer et al.   CLINICAL PHARMACOKINETICS

Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

(2009) Sam Maher et al.   ADVANCED DRUG DELIVERY REVIEWS