Distinct Signaling Pathways Between Human Macrophages and Primary Gingival Epithelial Cells by Aggregatibacter actinomycetemcomitans

Inflammasome‐associated cell death: Pyroptosis, apoptosis, and physiological implications

(2020) Kohsuke Tsuchiya   MICROBIOLOGY AND IMMUNOLOGY

Host inflammasome defense mechanisms and bacterial pathogen evasion strategies

(2019) Susan M Brewer et al.   CURRENT OPINION IN IMMUNOLOGY

Aggregatibacter Actinomycetemcomitans: Clinical Significance of a Pathobiont Subjected to Ample Changes in Classification and Nomenclature

(2019) Nørskov-Lauritsen et al.   Pathogens

Salivary Levels of NLRP3 Inflammasome-Related Proteins as Potential Biomarkers of Periodontal Clinical Status

(2017) Diana M. Isaza-Guzmán et al.   JOURNAL OF PERIODONTOLOGY

4E-BP1, a multifactor regulated multifunctional protein

(2016) Xiaoyu Qin et al.   CELL CYCLE

Aggregatibacter actinomycetemcomitans-Induced AIM2 Inflammasome Activation Is Suppressed by Xylitol in Differentiated THP-1 Macrophages

(2016) Seyeon Kim et al.   JOURNAL OF PERIODONTOLOGY

Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

(2016) M. F. Konig et al.   Science Translational Medicine

The expression of NLRP3, NLRP1 and AIM2 in the gingival tissue of periodontitis patients: RT-PCR study and immunohistochemistry

(2015) Fei Xue et al.   ARCHIVES OF ORAL BIOLOGY

The toxicity of theAggregatibacter actinomycetemcomitanscytolethal distending toxin correlates with its phosphatidylinositol-3,4,5-triphosphate phosphatase activity

(2015) Bruce J. Shenker et al.   CELLULAR MICROBIOLOGY

Immune–microbiota interactions in health and disease

(2015) Noah W. Palm et al.   CLINICAL IMMUNOLOGY

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activates the NLRP3 Inflammasome in Human Macrophages, Leading to the Release of Proinflammatory Cytokines

(2015) Bruce J. Shenker et al.   INFECTION AND IMMUNITY

Variability of the Dendritic Cell Response Triggered by Different Serotypes of Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis Is Toll-Like Receptor 2 (TLR2) or TLR4 Dependent

(2015) Jaime Díaz-Zúñiga et al.   JOURNAL OF PERIODONTOLOGY

The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity

(2015) Özlem Yilmaz et al.   PERIODONTOLOGY 2000

Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia

(2015) Ji-Yun Kim et al.   Oncotarget

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Streptococcus pneumoniae Induces Autophagy through the Inhibition of the PI3K-I/Akt/mTOR Pathway and ROS Hypergeneration in A549 Cells

(2015) Pu Li et al.   PLoS One

NLRP3 inflammasome is required for apoptosis of Aggregatibacter actinomycetemcomitans-infected human osteoblastic MG63 cells

(2014) Panyu Zhao et al.   ACTA HISTOCHEMICA

The cytolethal distending toxin of Aggregatibacter actinomycetemcomitans inhibits macrophage phagocytosis and subverts cytokine production

(2014) Ellen Sayuri Ando-Suguimoto et al.   CYTOKINE

Tyrosine phosphorylation in Toll-like receptor signaling

(2014) Saurabh Chattopadhyay et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Diverse Toll-Like Receptors Mediate Cytokine Production by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in Macrophages

(2014) Se-Ra Park et al.   INFECTION AND IMMUNITY

Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles Are Internalized in Human Host Cells and Trigger NOD1- and NOD2-Dependent NF-κB Activation

(2014) Bernard Thay et al.   INFECTION AND IMMUNITY

TLR2 Promoter Hypermethylation Creates Innate Immune Dysbiosis

(2014) M. Benakanakere et al.   JOURNAL OF DENTAL RESEARCH

Activation of Focal Adhesion Kinase by Salmonella Suppresses Autophagy via an Akt/mTOR Signaling Pathway and Promotes Bacterial Survival in Macrophages

(2014) Katherine A. Owen et al.   PLoS Pathogens

A Consortium of Aggregatibacter actinomycetemcomitans, Streptococcus parasanguinis, and Filifactor alocis Is Present in Sites Prior to Bone Loss in a Longitudinal Study of Localized Aggressive Periodontitis

(2013) D. H. Fine et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Microbial composition of atherosclerotic plaques

(2013) CA Calandrini et al.   ORAL DISEASES

Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity

(2013) Jonathan Ferrand et al.   Frontiers in Immunology

Aggregatibacter actinomycetemcomitans targets NLRP3 and NLRP6 inflammasome expression in human mononuclear leukocytes

(2012) Georgios N. Belibasakis et al.   CYTOKINE

Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment

(2012) Atsushi Arai et al.   JOURNAL OF CELL SCIENCE

Involvement of Toll-like receptor 2 in apoptosis of Aggregatibacter actinomycetemcomitans-infected THP-1 cells

(2012) Satsuki Kato et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Signaling transduction analysis in gingival epithelial cells after infection with Aggregatibacter actinomycetemcomitans

(2011) J.E. Umeda et al.   Molecular Oral Microbiology

Interaction of oral bacteria with gingival epithelial cell multilayers

(2011) B.C. Dickinson et al.   Molecular Oral Microbiology

Aggregatibacter actinomycetemcomitans Omp29 Is Associated with Bacterial Entry to Gingival Epithelial Cells by F-Actin Rearrangement

(2011) Mikihito Kajiya et al.   PLoS One

Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections

(2011) Manoranjan Sahoo et al.   TheScientificWorldJOURNAL

Cellular and molecular response of human macrophages exposed to Aggregatibacter actinomycetemcomitans leukotoxin

(2011) P Kelk et al.   Cell Death & Disease

Dual roles of NOD2 in TLR4-mediated signal transduction and -induced inflammatory gene expression in macrophages

(2010) Wen-Hsiang Tsai et al.   CELLULAR MICROBIOLOGY

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism

(2009) Panagiota G Stathopoulou et al.   BMC MICROBIOLOGY

Epithelial cell pro-inflammatory cytokine response differs across dental plaque bacterial species

(2009) Panagiota G. Stathopoulou et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae

(2009) G. Hajishengallis et al.   JOURNAL OF IMMUNOLOGY

The Role of Toll-Like Receptor 2 in the Recognition ofAggregatibacter actinomycetemcomitans

(2009) Valéria Gelani et al.   JOURNAL OF PERIODONTOLOGY

Characterization of the transduction pathway involved in c-fos and c-jun expression induced by Aggregatibacter actinomycetemcomitans lipopolysaccharides in human gingival fibroblasts

(2008) Gloria Gutiérrez-Venegas et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cytokines That Promote Periodontal Tissue Destruction

(2008) Dana Graves   JOURNAL OF PERIODONTOLOGY

IL-1β secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans is mainly caused by the leukotoxin

(2007) Peyman Kelk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY