Article
Public, Environmental & Occupational Health
Kimberly A. Bertrand, Katie M. O'Brien, Lauren B. Wright, Julie R. Palmer, William J. Blot, A. Heather Eliassen, Lynn Rosenberg, Sven Sandin, Deirdre Tobias, Elisabete Weiderpass, Wei Zheng, Anthony J. Swerdlow, Minouk J. Schoemaker, Hazel B. Nichols, Dale P. Sandler
Summary: The history of gestational diabetes mellitus (GDM) is not a risk factor for breast cancer in young women. The well-established protective effect of parity on the risk of ER-positive breast cancer persists even for pregnancies complicated by GDM.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Kirsten S. Dorans, Lydia A. Bazzano, Xingyan Li, Joshua D. Bundy, Ling Tian, Jiang He
Summary: This study compared cardiometabolic risk factors among parous women aged 20-44 in the United States with and without a history of gestational diabetes mellitus (GDM). The results showed that women with a history of GDM had less favorable cardiometabolic risk factor profiles, highlighting the importance of developing interventions to improve cardiovascular health in women with a history of GDM.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Environmental Sciences
Zhigang Li, Rongrong Xu, Zhanshan Wang, Nianfeng Qian, Yan Qian, Jianhao Peng, Xiaojing Zhu, Chen Guo, Xiaoqian Li, Qiujin Xu, Yongjie Wei
Summary: This study found that ozone exposure, especially in the first month before pregnancy, is associated with an increased risk of gestational diabetes mellitus (GDM). The odds of GDM also increase with increasing ozone concentration. These findings highlight the importance of stricter air pollution controls to improve the health of pregnant women and their offspring.
Article
Endocrinology & Metabolism
Yi-Xin Wang, Siwen Wang, Makiko Mitsunami, JoAnn E. Manson, Janet W. Rich-Edwards, Liang Wang, Cuilin Zhang, Jorge E. Chavarro
Summary: This study found that women with long or irregular menstrual cycles during mid-adulthood, but not in adolescence or young adulthood, were at higher risk of developing gestational diabetes mellitus (GDM).
Article
Endocrinology & Metabolism
Daryl J. Selen, Tanayott Thaweethai, Carolin C. M. Schulte, Sarah Hsu, Wei He, Kaitlyn James, Anjali Kaimal, James B. Meigs, Camille E. Powe
Summary: Gestational glucose intolerance (GGI), an abnormal initial gestational diabetes mellitus (GDM) screening test without a GDM diagnosis, is associated with an increased risk of future diabetes. Individuals with GGI have a higher risk of developing diabetes compared to those with normal glucose tolerance during pregnancy. Routine clinical data can be used to identify this unrecognized group who may benefit from enhanced diabetes screening and prevention.
Article
Public, Environmental & Occupational Health
Shih-Chun Pan, Ching-Chun Huang, Bing-Yu Chen, Wei-Shan Chin, Yue Leon Guo
Summary: This study aimed to determine whether air pollutants modify the effects of gestational diabetes mellitus (GDM) on the occurrence of diabetes mellitus (DM). The results showed that exposure to high levels of PM2.5 and O-3 increases the risk of DM, and GDM acts synergistically with PM2.5 exposure in DM development.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Immunology
Jiawei Xu, Xuan Lin, Ying Fang, Jing Cui, Zhi Li, Fang Yu, Libin Tian, Hongyan Guo, Xinyan Lu, Jiahao Ding, Lu Ke, Jiahui Wu
Summary: This study found that lifestyle interventions, including dietary guidance, health education, and weight management, have positive effects on pregnancy outcomes in women at high risk of gestational diabetes mellitus (GDM). The risk of GDM was reduced by 46.9% and the risk of pregnancy induced hypertension (PIH) was reduced by 74.2% in the intervention group compared to the control group. This highlights the importance of early screening and intervention for high-risk pregnant women.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Medicine, General & Internal
Grammata Kotzaeridi, Julia Blaetter, Daniel Eppel, Ingo Rosicky, Veronica Falcone, Gabriela Adamczyk, Tina Linder, Guelen Yerlikaya-Schatten, Karen Weisshaupt, Wolfgang Henrich, Andrea Tura, Christian S. Goebl
Summary: Women with a history of gestational diabetes mellitus show alterations in glucose metabolism at the beginning of a subsequent pregnancy, increasing the risk of gestational diabetes recurrence.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Endocrinology & Metabolism
Yumeng Tian, Ping Li
Summary: This article reviews the research progress in the use of genetic risk score (GRS) in diabetes mellitus in recent years and discusses future prospects.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Kalpana Bastola, Paivikki Koponen, Natalia Skogberg, Mika Gissler, Tarja Kinnunen
Summary: A study in Finland found that migrant women from South Asian, East Asian, and Middle Eastern/North African regions have a higher risk of gestational diabetes mellitus compared to Finnish origin women.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2021)
Review
Biochemistry & Molecular Biology
Julien Simon, Karine Goueslard, Sonia Bechraoui-Quantin, Patrick Arveux, Catherine Quantin
Summary: The association between gestational diabetes mellitus (GDM) and breast cancer (BC) risk remains controversial, with some studies suggesting an increased risk while others indicating a possible protective effect. Due to methodological shortcomings, caution should be taken when interpreting these conflicting results, and further research is needed to better understand the underlying mechanisms.
Article
Obstetrics & Gynecology
Yiling Wei, Andong He, Chaoping Tang, Haixia Liu, Ling Li, Xiaofeng Yang, Xiufang Wang, Fei Shen, Jia Liu, Jing Li, Ruiman Li
Summary: This study aimed to build and evaluate models for predicting gestational diabetes mellitus (GDM) using routine indexes. The results showed that the models had good discrimination and calibration in both the training and validation cohorts, indicating their potential use in predicting the risk of GDM in early pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Endocrinology & Metabolism
Mukkesh Kumar, Li Chen, Karen Tan, Li Ting Ang, Cindy Ho, Gerard Wong, Shu E. Soh, Kok Hian Tan, Jerry Kok Yen Chan, Keith M. Godfrey, Shiao-yng Chan, Mary Foong Fong Chong, John E. Connolly, Yap Seng Chong, Johan G. Eriksson, Mengling Feng, Neerja Karnani
Summary: This study evaluated the predictive ability of the UK NICE guidelines for GDM risk assessment in Singaporean women and found that they performed poorly. A non-invasive predictive model, comprising of four non-invasive factors, outperformed the UK NICE guidelines.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Medicine, General & Internal
Kymberleigh A. Pagel, Hoyin Chu, Rashika Ramola, Rafael F. Guerrero, Judith H. Chung, Samuel Parry, Uma M. Reddy, Robert M. Silver, Jonathan G. Steller, Lynn M. Yee, Ronald J. Wapner, Matthew W. Hahn, Sriraam Natarajan, David M. Haas, Predrag Radivojac
Summary: This cohort study found that the addition of polygenic risk scores (PRS) was associated with the stratified risk of gestational diabetes (GD) diagnosis among high-risk patient subgroups, suggesting the benefits of targeted PRS ascertainment to encourage early intervention.
Review
Nutrition & Dietetics
Yaolin Ren, Yuan Zeng, Yifan Wu, Jie Yu, Qian Zhang, Xinhua Xiao
Summary: This article reviews the role of maternal gut microbiota in offspring glucose metabolism. The differences in gut microbiota between healthy pregnant women and those with GDM have been established. Clinical studies and animal models support the hypothesis that the gut microbiota affects glucose metabolism in offspring, and interventions to improve glucose metabolism are discussed.
Article
Peripheral Vascular Disease
Benmai Luo, Yizhou Lin, Si Gao, Yali Lu, Yuxin Zhao, Juan Xie, Xin Zhang, Hong Zhu
Summary: This study evaluated the impact of the 2017 AAP Guidelines on pediatric hypertension prevalence estimates in Chinese children. Results showed a significant increase in hypertension prevalence and a decrease in prehypertension prevalence under the new criteria. The updated definitions particularly affected boys, overweight children, and older children in terms of prevalence estimation.
JOURNAL OF HUMAN HYPERTENSION
(2021)
Article
Pediatrics
Minning Cheng, Ying Yao, Yuxin Zhao, Yizhou Lin, Si Gao, Juan Xie, Xin Zhang, Hong Zhu
Summary: In this study, urban girls were found to experience menarche earlier than rural girls, and this urban-rural difference could not be explained by family income, parental education, weight status of the participants and their parents, participants' physical exercise, and sleeping hours. Higher parental education was associated with earlier onset of menarche, but this association disappeared after adjustment for living residence.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Peripheral Vascular Disease
Yuxin Zhao, Shuaixiang Zhang, Yue Yi, Ting Qu, Si Gao, Yizhou Lin, Hong Zhu
Summary: Based on a cohort study in Tianjin, China, this study explores the relationship between neutrophils-to-lymphocyte ratio (NLR) and the risk of cardiovascular diseases (CVDs), finding a significant association between NLR and the risk of CVDs.
JOURNAL OF HUMAN HYPERTENSION
(2023)