Article
Thermodynamics
Wei Guo, Lige Tong, Liuan Yang, Shujie Zhao, Shaowu Yin, Chuanping Liu, Li Wang
Summary: The drying kinetics of moisture-containing porous material at constant temperature and humidity were investigated in this study. It was found that the drying rate is linearly correlated with the moisture content, but decreases with an increase in the number of stacked layers. A new semitheoretical drying model was proposed and validated experimentally.
INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER
(2023)
Article
Environmental Sciences
Michiel T. O. Jonker
Summary: This study investigated the impact of freezing, freeze-drying, and grinding on the C-free of HOCs in field sediments determined with SPME. Freezing and subsequent grinding of samples increased the C-free of PAHs up to a factor of 16. It is suggested that these sample manipulations should be avoided before ex situ C-free determinations to prevent overestimation of risks.
Article
Chemistry, Medicinal
Israel Borges Sebastiao, Bakul Bhatnagar, Serguei Tchessalov
Summary: The study introduces an improved modeling framework to describe the fast freezing process of droplets in spray freeze-drying, offering insights on optimizing pharmaceutical production processes. Additionally, a simplified model is proposed for validation purposes.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Agricultural Engineering
Raphael N. Alolga, Richard Osae, Traore S. Ibrahim, Vitus Onoja, Maurice T. Apaliya, Emmanuel Kwaw, Feng-Qing Huang
Summary: This study investigated the impact of four drying methods on the metabolomes and quality characteristics of vacuum-assisted osmosonic-pretreated turmeric slices. The results showed that freeze drying method yielded the best outcomes in terms of all quality parameters examined. Relative humidity convective drying method ranked second in all quality characteristics assessed.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Review
Food Science & Technology
Chibuzo Stanley Nwankwo, Endurance Oghogho Okpomor, Nesa Dibagar, Marta Wodecki, Wiktor Zwierz, Adam Figiel
Summary: Freeze-drying is an excellent method for dehydration, but traditional freeze-drying systems face challenges in the food industry. Upgrading or developing conventional freeze-dryers is necessary. Hybrid freeze-drying methods have the potential to achieve shorter drying durations, lower costs, and environmental friendliness while maintaining the same nutritive and sensory qualities as traditional freeze-drying in specific circumstances.
Article
Chemistry, Applied
Yuan-yuan Liu, Wei-hong Sun, Bing-zheng Li, Nan Shang, Yong Wang, Wei-qiao Lv, Dong Li, Li-jun Wang
Summary: Platycodon grandiflorus roots were extracted and dried to produce four different powders, with the ultrasound-assisted extraction and freeze drying process leading to the highest nutritional value and antioxidant activity among the powders.
Article
Pharmacology & Pharmacy
Laurens Leys, Gust Nuytten, Pieter-Jan Van Bockstal, Thomas De Beer
Summary: Continuous spin freeze-drying allows for the implementation of several in-line process analytical technologies to control and optimize the freeze-drying process. Two methods were developed to control the freezing and drying phases at the individual vial level. Accurate control of the freezing rate and vial temperature resulted in uniform drying time between replicates.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Metallurgy & Metallurgical Engineering
Han-quan Zhang, Cheng-xin Liu, Man-man Lu, Hong Yu
Summary: The study revealed that the drying process of artificial magnetite green pellet can be divided into three stages, with drying temperature and hot airflow speed being significant factors while the diameter of the pellet has a minor impact. By applying various fitting models, it was found that the Correction Page (III) model accurately describes the drying kinetics of artificial magnetite green pellet.
JOURNAL OF CENTRAL SOUTH UNIVERSITY
(2021)
Article
Acoustics
Xin Xu, Lei Zhang, Yabin Feng, Cunshan Zhou, Abu ElGasim A. Yagoub, Hafida Wahia, Haile Ma, Jin Zhang, Yanhui Sun
Summary: The study found that ultrasound and different freeze-thawing pretreatments significantly reduced drying time and total energy consumption in vacuum freeze-drying, with the AT and US pretreatment methods having the greatest impact on drying efficiency and quality preservation of okra. Ultrasound was particularly effective in maintaining the quality characteristics of okra, while the combination of AT + US had the most variable effects on quality. AT and US pretreatment methods were found to be superior to others in terms of dry matter loss, chlorophyll degradation, and antioxidant capacity.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Engineering, Chemical
Qiaolan Sun, Zezhi Wang, Li Chen, Cunshan Zhou, Clinton Emek Okonkwo, Yuxin Tang, Aiping Lu, Qiaomin Lu
Summary: This study evaluated the effects of main drying temperature (constant temperature, variable temperature (VT)) on the drying characteristics and product quality of scallion in vacuum freeze-drying (VFD) technology. The results showed that the drying time of VT group was 48.38% shorter than that of -20 degrees C group, with brighter scallion samples, lower volume shrinkage and tissue structure damage, and higher bioactives content. Additionally, the VT-VFD scallion better retained its flavor after rehydration compared to the constant temperature-VFD scallion. Thus, VT drying can significantly improve the drying characteristics and product quality of VFD scallion.
Review
Pharmacology & Pharmacy
Ji Young Yu, Piyanan Chuesiang, Gye Hwa Shin, Hyun Jin Park
Summary: Liposomes have potential as drug delivery systems, but issues such as self-aggregation, coalescence, flocculation, and precipitation may occur during formulation or storage. Post-processing techniques like freeze drying, spray drying, and spray freeze drying have been used to increase the stability of liposomes. The use of protective agents to overcome limitations of each process is also crucial.
Article
Computer Science, Interdisciplinary Applications
Prakitr Srisuma, George Barbastathis, Richard D. Braatz
Summary: Freeze drying, also known as lyophilization, is a vacuum-sublimation drying process for pharmaceutical products. Microwave-assisted freeze drying is an alternative method that utilizes microwave irradiation to dry the product, reducing drying time by 70%-80%. This article provides exact and approximate analytical solutions for conventional, microwave-assisted, and hybrid freeze drying, serving as reference solutions for validation and offering computationally efficient and accurate results.
COMPUTERS & CHEMICAL ENGINEERING
(2023)
Article
Pharmacology & Pharmacy
Laurens Leys, Gust Nuytten, Joris Lammens, Pieter-Jan Van Bockstal, Jos Corver, Chris Vervaet, Thomas De Beer
Summary: The pharmaceutical industry is moving towards more continuous manufacturing techniques and improved process control through the implementation of process analytical technology tools. Near-infrared (NIR) spectroscopy was used to study desorption kinetics during the secondary drying step of continuous spin freeze-drying, leading to the development of an inline calibration model to predict residual moisture content and evaluate the impact of different process parameters on the drying rate. The study revealed that product temperature and cooling rate during spin freezing had significant effects on the drying rate, while chamber pressure during drying had no significant impact in the tested range.
Article
Biochemistry & Molecular Biology
Angeline Chua, The-Thien Tran, Siyu Pu, Jin-Won Park, Kunn Hadinoto
Summary: This study successfully developed a dry-powder form of the CUR-BSA nanoplex using sucrose as a cryoprotectant. Sucrose exhibited excellent cryoprotective activity, preserving the integrity of BSA and ensuring good aqueous reconstitution. While the aqueous reconstitution, CUR dissolution, and amorphous form of the nanoplex were minimally affected by elevated heat and humidity, the BSA payload decreased and protein aggregation increased after exposure. However, these adverse effects can be minimized by increasing the mass fraction of sucrose.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Applied
J. Alarcon-Moyano, D. Acuna, S. Matiacevich, L. Caballero, F. Melo, F. Quero, P. Diaz-Calderon
Summary: This study evaluated the physical-chemical properties and structure of cellulose nanocrystals (CNC) dried by two different methods: Spray-Drying (SD) or Freeze-Drying (FD). The results showed that the drying method influenced the size, aspect ratio, and sorption of CNC. However, it did not affect zeta potential, crystallinity, or degradation temperature. The study suggests that the drying method plays a role in modifying the physico-chemical properties of CNC.
FOOD HYDROCOLLOIDS
(2023)
Article
Engineering, Chemical
Timilehin Martins Oyinloye, Won Byong Yoon
Article
Engineering, Chemical
Timilehin Martins Oyinloye, Won Byong Yoon
Summary: Computational fluid dynamics (CFD) was used to investigate the deposition and printability of rice paste for 3D printing. The study found that a rice to water ratio of 100:80, ambient temperature of 47±5℃, and a nozzle diameter of 0.8 mm resulted in optimal printing conditions.
Review
Engineering, Chemical
Timilehin Martins Oyinloye, Won Byong Yoon
Summary: This paper mainly discusses the application of CFD simulation to optimize processing conditions for food 3D printing and explores three core processes associated with it. It also details the major achievements of CFD simulation in food 3D printing with varied food materials, as well as the problems and potential solutions encountered by modelers.
Article
Food Science & Technology
Won Byong Yoon, Jae Won Park, Hwabin Jung
Summary: This study investigated the anti-proteolytic effect of potato protein isolate (PPI) on the endogenous protease activity in Pacific whiting surimi. The results showed that the addition of 2% PPI significantly improved the gel quality and retained the gel structure and whiteness.
Article
Engineering, Chemical
Hwabin Jung, Myeong Gi Lee, Won Byong Yoon
Summary: The effects of container design on heat transfer and food quality during microwave heating were investigated. It was found that using a container with a center-perforated lid improved heating uniformity and final food quality. A simulation model was proposed to describe the microwave heating process.
Article
Engineering, Chemical
Hyeon Woo Park, Jae W. Park, Won Byong Yoon
Summary: Due to the lack of accuracy and repeatability in data obtained from conventional methods, a standardized method is needed to evaluate the material properties of surimi gels. A study was conducted using 250 batches of different surimi gels to investigate the relationships between different texture measurement methods. The results showed that the strain distributions of surimi gels with added ingredients were significantly different from those without added ingredients, and digital image correlation (DIC) analysis was an effective tool for evaluating these strain distribution characteristics.
Article
Engineering, Chemical
Hwabin Jung, Won Byong Yoon
Summary: This study investigates the effect of physical parameters on the flow patterns of soybeans with different moisture contents in cylindrical silos with varying orifice sizes. Experimental and simulation results show that the flow behavior of soybeans at different moisture contents can be accurately predicted. These findings are useful for designing silos for continuous food processing.
Article
Food Science & Technology
Hwabin Jung, Timilehin Martins Oyinloye, Won Byong Yoon
Summary: This study investigates the stress response characteristics of hydrocolloid mixture gel systems under large deformation based on texture and rheological measurements. The results show that an increase in the ratio of xanthan can improve the flexibility of the agarose network, resulting in a decrease in failure stress and an increase in failure strain. The ring tensile test was found to provide a more accurate calculation of the stress-strain relationship compared to the compression test.
Article
Polymer Science
Hwabin Jung, Timilehin Martins Oyinloye, Won Byong Yoon
Summary: This study analyzed the stress and strain properties of surimi gels with 72.49% moisture content under large deformation. Mechanical measurements were compared and validated using digital image correlation (DIC) and numerical simulations. The study demonstrated that DIC and numerical simulation can be effective tools in analyzing the textural properties of surimi gel.
