Importance of Mesoporous Silica Particle Size in the Stabilization of Amorphous Pharmaceuticals—The Case of Simvastatin

Mechanistic aspects of drug loading in liquisolid systems with hydrophilic lipid-based mixtures

(2020) Barbora Vraníková et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ultraslow Cooling for the Stabilization of Pharmaceutical Glasses

(2019) Kohsaku Kawakami   JOURNAL OF PHYSICAL CHEMISTRY B

Glass Transition Dynamics and Physical Stability of Amorphous Griseofulvin in Binary Mixtures with Low-Tg Excipients

(2019) Wenkang Tu et al.   MOLECULAR PHARMACEUTICS

Molecular dynamics, viscoelastic properties and physical stability studies of a new amorphous dihydropyridine derivative with T-type calcium channel blocking activity

(2019) Justyna Knapik-Kowalczuk et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Scaling laws and size effects for amorphous crystallization kinetics: Constraints imposed by nucleation and growth specificities

(2018) Marc Descamps et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica

(2018) Nele-Johanna Hempel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mesoporous systems for poorly soluble drugs – recent trends

(2018) Joakim Riikonen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hot Melt Extrusion as Solvent-Free Technique for a Continuous Manufacturing of Drug-Loaded Mesoporous Silica

(2018) Natalja Genina et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Can Storage Time Improve the Physical Stability of Amorphous Pharmaceuticals with Tautomerization Ability Exposed to Compression? The Case of a Chloramphenicol Drug

(2018) Justyna Knapik-Kowalczuk et al.   MOLECULAR PHARMACEUTICS

Co-Stabilization of Amorphous Pharmaceuticals—The Case of Nifedipine and Nimodipine

(2018) Justyna Knapik-Kowalczuk et al.   MOLECULAR PHARMACEUTICS

Influence of Low-Molecular-Weight Excipients on the Phase Behavior of PVPVA64 Amorphous Solid Dispersions

(2018) Kristin Lehmkemper et al.   PHARMACEUTICAL RESEARCH

Advances in Coamorphous Drug Delivery Systems

(2018) Qin Shi et al.   Acta Pharmaceutica Sinica B

Enhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges

(2018) Kristen E. Bremmell et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Atorvastatin as a Promising Crystallization Inhibitor of Amorphous Probucol: Dielectric Studies at Ambient and Elevated Pressure

(2017) J. Knapik-Kowalczuk et al.   MOLECULAR PHARMACEUTICS

A New Method To Identify Physically Stable Concentration of Amorphous Solid Dispersions (I): Case of Flutamide + Kollidon VA64

(2017) K. Chmiel et al.   MOLECULAR PHARMACEUTICS

Molecular Factors Governing the Liquid and Glassy States Recrystallization of Celecoxib in Binary Mixtures with Excipients of Different Molecular Weights

(2017) K. Grzybowska et al.   MOLECULAR PHARMACEUTICS

Crystallization of supercooled fenofibrate studied at ambient and elevated pressures

(2017) Grzegorz Szklarz et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Recent developments in the experimental investigations of relaxations in pharmaceuticals by dielectric techniques at ambient and elevated pressure

(2016) Katarzyna Grzybowska et al.   ADVANCED DRUG DELIVERY REVIEWS

Ordered mesoporous silica to enhance the bioavailability of poorly water-soluble drugs: Proof of concept in man

(2016) Katarina Bukara et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Pore size effect on the stabilization of amorphous drug in a mesoporous material: Insights from molecular simulation

(2016) Yin Yani et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Molecular Dynamics and Physical Stability of Amorphous Nimesulide Drug and Its Binary Drug–Polymer Systems

(2016) J. Knapik et al.   MOLECULAR PHARMACEUTICS

Long-Term Physical Stability of PVP- and PVPVA-Amorphous Solid Dispersions

(2016) Kristin Lehmkemper et al.   MOLECULAR PHARMACEUTICS

Stabilization of the Amorphous Ezetimibe Drug by Confining Its Dimension

(2016) J. Knapik et al.   MOLECULAR PHARMACEUTICS

Universal Behavior of Dielectric Responses of Glass Formers: Role of Dipole-Dipole Interactions

(2016) M. Paluch et al.   PHYSICAL REVIEW LETTERS

Surface Effects on the Crystallization of Ritonavir Glass

(2015) Kohsaku Kawakami   JOURNAL OF PHARMACEUTICAL SCIENCES

Correlation between Glass-Forming Ability and Fragility of Pharmaceutical Compounds

(2015) Kohsaku Kawakami et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular Dynamics and Physical Stability of Coamorphous Ezetimib and Indapamide Mixtures

(2015) J. Knapik et al.   MOLECULAR PHARMACEUTICS

Insoluble drug delivery strategies: review of recent advances and business prospects

(2015) Sandeep Kalepu et al.   Acta Pharmaceutica Sinica B

Dissolution Improvement of Simvastatin by Surface Solid Dispersion Technology

(2015) Monica Rao et al.   DISSOLUTION TECHNOLOGIES

Isothermal Cold Crystallization Kinetics Study of Sildenafil

(2014) K. Kolodziejczyk et al.   CRYSTAL GROWTH & DESIGN

Physical Stability of the Amorphous Anticholesterol Agent (Ezetimibe): The Role of Molecular Mobility

(2014) J. Knapik et al.   MOLECULAR PHARMACEUTICS

Assessment of the Amorphous “Solubility” of a Group of Diverse Drugs Using New Experimental and Theoretical Approaches

(2014) Luis Almeida e Sousa et al.   MOLECULAR PHARMACEUTICS

Relationship between Crystallization Tendencies during Cooling from Melt and Isothermal Storage: Toward a General Understanding of Physical Stability of Pharmaceutical Glasses

(2014) Kohsaku Kawakami et al.   MOLECULAR PHARMACEUTICS

Synergistic role of self-emulsifying lipids and nanostructured porous silica particles in optimizing the oral delivery of lovastatin

(2014) Shasha Rao et al.   Nanomedicine

Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug–polymer mixtures

(2013) Petra A. Priemel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impact of surface area of silica particles on dissolution rate and oral bioavailability of poorly water soluble drugs: A case study with aceclofenac

(2013) Dinesh Kumar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Relaxation Dynamics and Crystallization Study of Sildenafil in the Liquid and Glassy States

(2013) K. Kolodziejczyk et al.   MOLECULAR PHARMACEUTICS

Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs

(2012) Kohsaku Kawakami   ADVANCED DRUG DELIVERY REVIEWS

Emerging trends in the stabilization of amorphous drugs

(2012) Riikka Laitinen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Evaluation of Drug Supersaturation by Thermodynamic and Kinetic Approaches for the Prediction of Oral Absorbability in Amorphous Pharmaceuticals

(2012) Shunsuke Ozaki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Enhancement of Amorphous Celecoxib Stability by Mixing It with Octaacetylmaltose: The Molecular Dynamics Study

(2012) K. Grzybowska et al.   MOLECULAR PHARMACEUTICS

Molecular Dynamics in Supercooled Liquid and Glassy States of Antibiotics: Azithromycin, Clarithromycin and Roxithromycin Studied by Dielectric Spectroscopy. Advantages Given by the Amorphous State

(2012) K. Adrjanowicz et al.   MOLECULAR PHARMACEUTICS

Evaluation of amorphous solid dispersion properties using thermal analysis techniques

(2011) Jared A. Baird et al.   ADVANCED DRUG DELIVERY REVIEWS

Role of α-Relaxation on Crystallization of Amorphous Celecoxib aboveTgProbed by Dielectric Spectroscopy

(2011) Ajay K. R. Dantuluri et al.   MOLECULAR PHARMACEUTICS

Molecular Dynamics and Physical Stability of Amorphous Anti-Inflammatory Drug: Celecoxib

(2010) K. Grzybowska et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Solubility Advantage of Amorphous Pharmaceuticals: II. Application of Quantitative Thermodynamic Relationships for Prediction of Solubility Enhancement in Structurally Diverse Insoluble Pharmaceuticals

(2010) Sharad B. Murdande et al.   PHARMACEUTICAL RESEARCH

Stabilization of the amorphous state of pharmaceuticals in nanopores

(2008) G. T. Rengarajan et al.   JOURNAL OF MATERIALS CHEMISTRY