Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells

Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance

(2019) Daiana Vitale et al.   FEBS Journal

Role of cell surface proteoglycans in cancer immunotherapy

(2019) Nancy A. Espinoza-Sánchez et al.   SEMINARS IN CANCER BIOLOGY

Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character

(2018) Ainara Crespo et al.   BMC CANCER

Extracellular matrix functions in lung cancer

(2018) Martin Götte et al.   MATRIX BIOLOGY

Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways

(2017) Sherif Abdelaziz Ibrahim et al.   Molecular Cancer

Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth

(2017) Argyris Spyrou et al.   MOLECULAR CANCER THERAPEUTICS

Oleuropein represses the radiation resistance of ovarian cancer by inhibiting hypoxia and microRNA-299-targetted heparanase expression

(2017) Yubai Xing et al.   Food & Function

Heparanase: From basic research to therapeutic applications in cancer and inflammation

(2016) Israel Vlodavsky et al.   DRUG RESISTANCE UPDATES

Heparan sulfate proteoglycans undergo differential expression alterations in right sided colorectal cancer, depending on their metastatic character

(2015) Iván Fernández-Vega et al.   BMC CANCER

Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy

(2015) Anna Shteingauz et al.   CANCER RESEARCH

MicroRNA regulation of proteoglycan function in cancer

(2014) Sherif A. Ibrahim et al.   FEBS Journal

HS3ST2modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression

(2014) Archana Vijaya Kumar et al.   INTERNATIONAL JOURNAL OF CANCER

Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling

(2014) Sherif A. Ibrahim et al.   PLoS One

Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models

(2013) G. Cassinelli et al.   BIOCHEMICAL PHARMACOLOGY

An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization

(2013) Tsukasa Shibue et al.   CANCER CELL

The heparanase/syndecan-1 axis in cancer: mechanisms and therapies

(2013) Vishnu C. Ramani et al.   FEBS Journal

Syndecan-1 modulates β-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiation

(2013) Hebatallah Hassan et al.   FEBS Journal

Characterization of Heparanase-induced Phosphatidylinositol 3-Kinase-AKT Activation and Its Integrin Dependence

(2013) Anjum Riaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells

(2013) Vinitha Richard et al.   Biomed Research International

The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment

(2012) Alina Filatova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Flow cytometry in cancer stem cell analysis and separation

(2012) Burkhard Greve et al.   CYTOMETRY PART A

Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism

(2012) Sherif A. Ibrahim et al.   INTERNATIONAL JOURNAL OF CANCER

The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity

(2012) M. Angela Nieto et al.   SEMINARS IN CANCER BIOLOGY

Role of Heparanase in Radiation-Enhanced Invasiveness of Pancreatic Carcinoma

(2011) A. Meirovitz et al.   CANCER RESEARCH

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

(2011) Immanuel Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle progression and apoptosisviaNotch-1 and p21WAF1/CIP1

(2010) Martin Götte et al.   INTERNATIONAL JOURNAL OF CANCER

Tumorigenic and adhesive properties of heparanase

(2010) Flonia Levy-Adam et al.   SEMINARS IN CANCER BIOLOGY

Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells

(2010) LON D. RIDGWAY et al.   Experimental and Therapeutic Medicine

Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors

(2008) Yosuke Hashimoto et al.   BMC CANCER

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression

(2008) Sara Cabodi et al.   JOURNAL OF CELLULAR PHYSIOLOGY