IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer

Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12

(2020) Juan P. Arab et al.   JOURNAL OF HEPATOLOGY

Effects of IGFBP‐3 and GalNAc‐T14 on proliferation and cell cycle of glioblastoma cells and its mechanism

(2019) Jiao Yang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

IGFBP-3 Interacts with the Vitamin D Receptor in Insulin Signaling Associated with Obesity in Visceral Adipose Tissue

(2017) Inmaculada Moreno-Santos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IGFBP-3 Gene Methylation in Primary Tumor Predicts Recurrence of Stage II Colorectal Cancers

(2016) Tao Fu et al.   ANNALS OF SURGERY

Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses

(2016) Hae-Ki Min et al.   FASEB JOURNAL

Caveolin-1 in the regulation of cell metabolism: a cancer perspective

(2016) Zeribe Chike Nwosu et al.   Molecular Cancer

miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia

(2016) Wei Zhou et al.   ONCOLOGY REPORTS

Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-β

(2015) Evert Njomen et al.   PROTEIN AND PEPTIDE LETTERS

GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma

(2015) Ok-Seon Kwon et al.   Oncotarget

Epigenetic regulation of insulin-like growth factor binding protein-3 (IGFBP-3) in cancer

(2015) Claire M Perks et al.   Journal of Cell Communication and Signaling

Methylation status ofIGFBP-3as a useful clinical tool for deciding on a concomitant radiotherapy

(2014) Olga Pernía et al.   Epigenetics

IGFBP-3: A cell fate pivot in cancer and disease

(2014) Michael A. Johnson et al.   GROWTH HORMONE & IGF RESEARCH

IGFBP3 Methylation Is a Novel Diagnostic and Predictive Biomarker in Colorectal Cancer

(2014) Lucia Perez-Carbonell et al.   PLoS One

A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer

(2013) Zsuzsanna Mihály et al.   BREAST CANCER RESEARCH AND TREATMENT

Tobacco specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone suppresses a newly identified anti-tumor IGFBP-3/IGFBP-3R system in lung cancer cells

(2013) Aki Harada et al.   LUNG CANCER

IGFBP-3 Inhibits Cytokine-Induced Insulin Resistance and Early Manifestations of Atherosclerosis

(2013) Lathika Mohanraj et al.   PLoS One

IGFBP-3 sensitizes antiestrogen-resistant breast cancer cells through interaction with GRP78

(2012) Chao Li et al.   CANCER LETTERS

IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments

(2012) S Grkovic et al.   ONCOGENE

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Insulin-like growth factor-binding protein-3 suppresses tumor growth via activation of caspase-dependent apoptosis and cross-talk with NF-κB signaling

(2011) Jinfeng Han et al.   CANCER LETTERS

IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer

(2011) H. H. Mehta et al.   CANCER RESEARCH

ER Stress and Apoptosis: A New Mechanism for Retinal Cell Death

(2011) Guangjun Jing et al.   Experimental Diabetes Research

Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer

(2010) Angela R. Ingermann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perspectives in mammalian IGFBP-3 biology: local vs. systemic action

(2009) Paulette M. Yamada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of adipocyte differentiation by insulin-like growth factor-binding protein-3

(2009) Sophie S. Y. Chan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Unraveling Insulin-Like Growth Factor Binding Protein-3 Actions in Human Disease

(2009) Sherryline Jogie-Brahim et al.   ENDOCRINE REVIEWS

IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer

(2009) I Ibanez de Caceres et al.   ONCOGENE

The metal-binding domain of IGFBP-3 selectively delivers therapeutic molecules into cancer cells

(2008) Anja Huq et al.   ANTI-CANCER DRUGS

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Induction of Apoptosis in Human Prostate Cancer Cells by Insulin-Like Growth Factor Binding Protein-3 Does Not Require Binding to Retinoid X Receptor-α

(2007) Giovanna Zappala et al.   ENDOCRINOLOGY