Article
Biochemistry & Molecular Biology
Amir Barzegar Behrooz, Zahra Talaie, Fatemeh Jusheghani, Marek J. Los, Thomas Klonisch, Saeid Ghavami
Summary: Glioblastoma (GBM) is a devastating type of brain tumor, and targeting the Wnt/β-catenin and PI3K/Akt/mTOR (PAM) signaling pathways, which play crucial roles in GBM progression and invasion, may provide important advancements in alternative treatment strategies for GBM.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar
Summary: The PI3K/AKT/mTOR (PAM) signaling pathway plays a crucial role in cell survival, growth, and cell cycle progression. Dysregulation of this pathway is associated with cancer development and resistance to therapy. This review focuses on the major dysregulations in the PAM signaling pathway in cancer and discusses strategies for overcoming treatment resistance. The role of PAM signaling in immunology and immunotherapies is also discussed.
Review
Pharmacology & Pharmacy
Nazanin Momeni Roudsari, Naser-Aldin Lashgari, Saeideh Momtaz, Shaghayegh Abaft, Fatemeh Jamali, Pardis Safaiepour, Kiyana Narimisa, Gloria Jackson, Anusha Bishayee, Nima Rezaei, Amir Hossein Abdolghaffari, Anupam Bishayee
Summary: The importance of the PI3K/Akt/mTOR pathway in prostate cancer treatment and the clinical applications of natural agents and small molecule inhibitors targeting this pathway are discussed in the study. Research suggests that natural mTOR inhibitors can interfere with the PI3K/Akt/mTOR pathway through multiple mechanisms, with inhibition of Akt and suppression of mTOR 1 activity being the main therapeutic approaches. Combination therapy has been shown to improve the efficacy of these inhibitors in suppressing prostate cancer progression or overcoming resistance by cancer cells.
Article
Biochemistry & Molecular Biology
Kostas A. Papavassiliou, Athanasios G. Papavassiliou
Summary: GBM, a deadly brain tumor, has limited treatment options and mTOR pathway plays a crucial role in its pathogenesis. Initial attempts with first-generation mTOR inhibitors lacked significant success in clinical trials, but the development of next-generation inhibitors offers new hope for the potential of mTOR inhibitors in GBM.
Review
Biochemistry & Molecular Biology
Torki A. Zughaibi, Mohd Suhail, Mohammad Tarique, Shams Tabrez
Summary: Cancer is a leading cause of death globally, and current therapies often fail due to side effects, drug resistance, and limited accessibility. Studies have shown that flavonoids, found in herbal/plant sources, may act as complementary treatments for cancer patients with their broad biological properties and anticancer activity by affecting different signaling cascades.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Cell Biology
Kunrui Zhu, Yanqi Wu, Ping He, Yu Fan, Xiaorong Zhong, Hong Zheng, Ting Luo
Summary: Phosphatidylinositol 3-kinase (PI3K), protein kinase B (PKB/AKT) and mechanistic target of rapamycin (mTOR) (PAM) pathways play important roles in breast tumorigenesis and offer potential targets for cancer therapy.
Review
Biochemistry & Molecular Biology
Yu-Chieh Su, Wei-Chang Lee, Chih-Chun Wang, Shyh-An Yeh, Wen-Hui Chen, Po-Jen Chen
Summary: This review discusses the oncogenic significance of PI3K/AKT/mTOR signaling in HNSCC radiotherapy resistance and highlights the therapeutic potential of small molecule inhibitors against this pathway for radiosensitization in HNSCC treatment. It provides a mechanistic framework for the development of new drugs for radiosensitization in HNSCC radiotherapy via targeting the PI3K/AKT/mTOR signaling pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, Research & Experimental
Maryam Akbarzadeh, Ainaz Mihanfar, Shabnam Akbarzadeh, Bahman Yousefi, Maryam Majidinia
Summary: The PI3K/AKT/mTOR signaling pathway plays a crucial role in cancer and has been found to interact with miRNAs, which is important for understanding cancer biology.
Review
Biochemistry & Molecular Biology
Vivek Makwana, Santosh Rudrawar, Shailendra Anoopkumar-Dukie
Summary: Hexosamine biosynthetic (HBP) and PI3K/AKT/mTOR pathways play crucial roles in the proliferation and survival of prostate cancer cells by increasing androgen receptor expression and protein levels. Inhibition of a single pathway is insufficient to halt disease progression, suggesting that targeting multiple pathways at common junctions may be beneficial for effective management of prostate cancer.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2021)
Article
Pharmacology & Pharmacy
Hao Yan, Zhenhao Fu, Pingxin Lin, Yu Gu, Jin Cao, Ye Li
Summary: Glioblastoma is a highly deadly malignant nervous system tumor that is difficult to treat. This study investigated the inhibitory effects of the compound DCV on glioblastoma and discovered its potential as a candidate for developing more potent chemotherapy drugs.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Neurosciences
Hai Yu, Xiaodong Li, Yi Li, Tuo Wang, Maode Wang, Ping Mao
Summary: Increasing evidence has shown that ALDH1A3 is closely associated with tumorigenesis, therapy resistance, and prognosis in various cancers. This study demonstrates that ALDH1A3 is highly expressed in GBM cells and plays a critical role in their proliferation and radioresistance. The study also identifies miR-4524b-5p as an upstream regulator of ALDH1A3 and shows that overexpression of miR-4524b-5p reduces proliferation and radioresistance in GBM cells. Targeting the miR-4524b-5p and ALDH1A3 axis could be a promising therapeutic strategy for treating GBM.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Review
Biochemistry & Molecular Biology
Carla L. Alves, Henrik J. Ditzel
Summary: The PI3K/AKT/mTOR pathway plays a crucial role in estrogen receptor-positive breast cancer tumorigenesis and drug resistance, making it a highly attractive therapeutic target. Several inhibitors targeting this pathway are currently under clinical development. The recent approval of the PIK3CA isoform-specific inhibitor alpelisib and the pan-AKT inhibitor capivasertib, in combination with fulvestrant, has provided new treatment options for advanced estrogen receptor-positive breast cancer patients. However, the clinical development of multiple inhibitors and incorporating CDK4/6 inhibitors into the standard treatment has complicated the personalization of therapy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Stefano Ratti, Raffaella Mauro, Cristina Rocchi, Sara Mongiorgi, Giulia Ramazzotti, Mauro Gargiulo, Lucia Manzoli, Lucio Cocco, Roberta Fiume
Summary: This review examines the importance of critical enzymes such as PI3K, AKT, and mTOR in the maturation and failure of arteriovenous fistula (AVF) for haemodialysis treatment. These enzymes play a role in various cellular activities and are associated with multiple diseases. They are also druggable targets, which can be targeted to control specific aspects of AVF and provide more personalized therapy.
Review
Biochemistry & Molecular Biology
Krisida Cerma, Federico Piacentini, Luca Moscetti, Monica Barbolini, Fabio Canino, Antonio Tornincasa, Federica Caggia, Sara Cerri, Alessia Molinaro, Massimo Dominici, Claudia Omarini
Summary: Breast cancer is the most common and deadliest cancer in women, and new drugs often have limited clinical benefits. Mutations in the PI3K/AKT/mTOR pathway are frequent in breast cancer and contribute to aggressive tumor behavior and treatment resistance. Understanding the role of PI3K-mTORC1/C2 mutations in different breast cancer subtypes is crucial for improving clinical outcomes and treatment efficacy. A broad knowledge of tumor biology will be essential for personalized breast cancer therapy in the era of precision medicine.
Article
Oncology
Kasun Wanigasooriya, Joao D. Barros-Silva, Louise Tee, Mohammed E. El-asrag, Agata Stodolna, Oliver J. Pickles, Joanne Stockton, Claire Bryer, Rachel Hoare, Celina M. Whalley, Robert Tyler, Toritseju Sillo, Christopher Yau, Tariq Ismail, Andrew D. Beggs
Summary: This study investigates the mechanisms of resistance to chemoradiotherapy in rectal cancer using patient derived organoid models. The upregulation of PI3K/AKT/mTOR pathway is found to contribute to radioresistance, and its targeted pharmacological inhibition leads to significant improvement in cancer cell sensitivity to radiotherapy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Infectious Diseases
Luke B. Snell, Chloe L. Fisher, Usman Taj, Oliver Stirrup, Blair Merrick, Adela Alcolea-Medina, Themoula Charalampous, Adrian W. Signell, Harry D. Wilson, Gilberto Betancor, Mark Tan Kia Ik, Emma Cunningham, Penelope R. Cliff, Suzanne Pickering, Rui Pedro Galao, Rahul Batra, Stuart J. D. Neil, Michael H. Malim, Katie J. Doores, Sam T. Douthwaite, Gaia Nebbia, Jonathan D. Edgeworth, Ali R. Awan
Summary: Analysis of viral genome sequences and epidemiological data in a large healthcare institution during the early stages of the COVID-19 pandemic revealed 44 transmission clusters, with genomics playing a crucial role in accurately resolving these clusters. Evidence suggests that unidentified cases, such as healthcare workers or asymptomatic patients, may be important vectors of transmission.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Article
Immunology
Rodric Francis, Harriet Billam, Mitch Clarke, Carl Yates, Theocharis Tsoleridis, Louise Berry, Nikunj Mahida, William L. Irving, Christopher Moore, Nadine Holmes, Jonathan K. Ball, Matthew Loose, C. Patrick McClure
Summary: Utilizing whole-genome sequencing technology to analyze SARS-CoV-2 clusters in hospital settings helps to identify the origin and transmission pathways of outbreaks, enabling timely intervention measures. Additionally, this technology can also exclude false nosocomial transmission events, saving healthcare resources.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Virology
Florencia A. T. Boshier, Juanita Pang, Justin Penner, Matthew Parker, Nele Alders, Alasdair Bamford, Louis Grandjean, Stephanie Grunewald, James Hatcher, Timothy Best, Caroline Dalton, Patricia Dyal Bynoe, Claire Frauenfelder, Jutta Koeglmeier, Phoebe Myerson, Sunando Roy, Rachel Williams, Thushan Silva, Richard A. Goldstein, Judith Breuer
Summary: The study found that remdesivir treatment suppressed viral load in some patients but not in others, with additional effects on viral replication observed in certain cases. The presence of discrete viral populations in the lung may limit the efficacy of remdesivir in vivo.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Infectious Diseases
Katherine A. Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A. Sinnathamby, Shirin Aliabadi, Shaun R. Seaman, Ross J. Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M. Presanis, Gavin Dabrera
Summary: A study in England found that patients with COVID-19 infected with the delta variant were more likely to be admitted to hospital or attend emergency care compared to those infected with the alpha variant. This suggests that outbreaks of the delta variant in unvaccinated populations may pose a greater burden on healthcare services.
LANCET INFECTIOUS DISEASES
(2022)
Article
Pathology
Stephen P. Kidd, Daniel Burns, Bryony Armson, Andrew D. Beggs, Emma L. A. Howson, Anthony Williams, Gemma Snell, Emma L. Wise, Alice Goring, Zoe Vincent-Mistiaen, Seden Grippon, Jason Sawyer, Claire Cassar, David Cross, Thomas Lewis, Scott M. Reid, Samantha Rivers, Joe James, Paul Skinner, Ashley Banyard, Kerrie Davies, Anetta Ptasinska, Celina Whalley, Jack Ferguson, Claire Bryer, Charlie Poxon, Andrew Bosworth, Michael Kidd, Alex Richter, Jane Burton, Hannah Love, Sarah Fouch, Claire Tillyer, Amy Sowood, Helen Patrick, Nathan Moore, Michael Andreou, Nick Morant, Rebecca Houghton, Joe Parker, Joanne Slater-Jefferies, Ian Brown, Cosima Gretton, Zandra Deans, Deborah Porter, Nicholas J. Cortes, Angela Douglas, Sue L. Hill, Keith M. Godfrey, Veronica L. Fowler
Summary: This study validates an improved extraction-free RT-LAMP method and reports the clinical performance of four RT-LAMP assay formats for SARS-CoV-2 detection. The results demonstrate that RT-LAMP is applicable to a variety of use cases, including frequent, interval-based direct testing of saliva from asymptomatic individuals.
JOURNAL OF MOLECULAR DIAGNOSTICS
(2022)
Article
Cardiac & Cardiovascular Systems
Ewen A. Griffiths
Summary: Handsewn anastomoses are associated with higher rates of anastomotic failure compared to stapled anastomoses, particularly in neck anastomoses. There is minimal difference between techniques for chest anastomoses. Further research into standardization of anastomotic approach and techniques may lead to improved outcomes.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Surgery
K. Wanigasooriya, D. R. Sarma, P. Woods, P. O'Connor, A. Matthews, M. I. Aslam, C. Dando, H. Ferguson, J. Francombe, N. Lal, P. D. Murphy, T. Papettas, S. Ramcharan, K. Busby
Summary: The study evaluated the use of virtual clinic appointments for lower gastrointestinal (LGI) clinics during the COVID-19 pandemic in the UK. The results showed that virtual appointments were effective, safe, and had positive environmental and financial impacts. The waiting times and cancer detection rates were similar to face-to-face appointments, and there were cost and emissions savings.
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
(2023)
Article
Oncology
Kasun Wanigasooriya, Joao D. Barros-Silva, Louise Tee, Mohammed E. El-asrag, Agata Stodolna, Oliver J. Pickles, Joanne Stockton, Claire Bryer, Rachel Hoare, Celina M. Whalley, Robert Tyler, Toritseju Sillo, Christopher Yau, Tariq Ismail, Andrew D. Beggs
Summary: This study investigates the mechanisms of resistance to chemoradiotherapy in rectal cancer using patient derived organoid models. The upregulation of PI3K/AKT/mTOR pathway is found to contribute to radioresistance, and its targeted pharmacological inhibition leads to significant improvement in cancer cell sensitivity to radiotherapy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Lennard Y. W. Lee, Michael Tilby, Thomas Starkey, Maria C. Ionescu, Alex Burnett, Rosie Hattersley, Sam Khan, Martin Little, Justin K. H. Liu, James R. Platt, Arvind Tripathy, Isabella Watts, Sophie Therese Williams, Nathan Appanna, Youssra Al-Hajji, Matthew Barnard, Liza Benny, Andrew Buckley, Emma Cattell, Vinton Cheng, James Clark, Leonie Eastlake, Kate Gerrand, Qamar Ghafoor, Simon Grumett, Catherine Harper-Wynne, Rachel Kahn, Alvin J. X. Lee, Anna Lydon, Hayley McKenzie, Hari Panneerselvam, Jennifer Pascoe, Grisma Patel, Vijay Patel, Vanessa Potter, Amelia Randle, Anne S. Rigg, Tim Robinson, Rebecca Roylance, Tom Roques, Stefan Rozmanowski, Rene L. Roux, Ketan Shah, Martin Sintler, Harriet Taylor, Tania Tillett, Mark Tuthill, Sarah Williams, Andrew Beggs, Tim Iveson, Siow Ming Lee, Gary Middleton, Mark Middleton, Andrew S. Protheroe, Matthew W. Fittall, Tom Fowler, Peter Johnson
Summary: Accurate identification of patient groups with the lowest level of protection following COVID-19 vaccination is important. This study aims to evaluate the association between spike protein antibody vaccine response and the risk of SARS-CoV-2 breakthrough infection or hospitalization among patients with cancer.
Article
Gastroenterology & Hepatology
Sofie Bosch, Animesh Acharjee, Mohammed Nabil Quraishi, Irene Bijnsdorp, Patricia Rojas, Abdellatif Bakkali, Erwin Ew Jansen, Pieter Stokkers, Johan Kuijvenhoven, Thang Pham, Andrew D. Beggs, Connie R. Jimenez, Eduard A. Struys, Georgios Gkoutos, Tim Gj de Meij, Nanne Kh de Boer
Summary: This study aimed to explore potential biomarker panels for colorectal cancer (CRC) and adenoma detection, as well as investigate the interaction between gut microbiota and human metabolism in the presence of these lesions. By integrating data from multiple omics platforms, new biomarker panels were identified that outperformed the current screening method of hemoglobin, potentially improving noninvasive screening for CRC.
Review
Biochemistry & Molecular Biology
Toritseju O. Sillo, Andrew D. Beggs, Gary Middleton, Akinfemi Akingboye
Summary: There is increasing evidence that the microbiome has a direct role in modulating the immune response against cancer, both at the gut level and systemically. Differences in the gut microbiota are correlated with differences in immunotherapy responses in various types of cancer. The gut microbiome is significantly different between DNA mismatch repair-deficient (dMMR) and proficient (pMMR) colorectal cancer, and these differences may contribute to varied responses to immunotherapy. Targeting the microbiome could enhance the response to immunotherapy and improve patient selection. This paper reviews the existing literature on the role of the microbiome in immunotherapy response in dMMR and pMMR colorectal cancer, explores potential causal relationships, and discusses future research directions in this field.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Letter
Surgery
Maria Picciochi, James C. Glasbey, Elizabeth Li, Sivesh K. Kamarajah, Dmitri Nepogodiev, Joana F. F. Simoes, Aneel Bhangu, Arjun Nathan, Nizar S. M. Ismail, Amer J. Durrani, Fanourios Georgiades, Ignatius Liew, Mamun D. Dornseifer, Chetan D. Parmar, Angelos G. Kolias, Efstratia A. Baili, Ashwani Kumar Nugur, Erminia Albanese, Marios Ghobrial, Andreas K. Demetriades, Joseph P. Attwood, Baljit Singh, Ciaran M. Barlow, Sheila M. Fraser, Manas K. Dube, Avinash Aujayeb, Dinesh K. Thekkinkattil, Abraham J. Botha, Tosin O. Akinyemi, W. K. E. Peng, Salah A. Hammouche, Muyed K. A. Mohamed, Mahmoud K. A. Elmesalmi, Maria G. Cannoletta, Kai Yuen Wong, Hassan M. T. Fawi, Suk F. Cheng, Funlayo O. Odejinmi, Hugo R. M. Layard Horsfall, Nikolaos Machairas, Rory C. Cuthbert, Shahbaz S. Malik, Rory G. Callan, Richard J. Egan, Nader N. Moawad, David W. Ferguson, Nathan Grundy, Michelle L. Collins, Jonathan B. T. Herron, Chetan Khatri, Sophia E. Lewis, Tariq Alhammali, Andrew J. Beamish, Kiran K. Singisetti, Joseph Shalhoub, Chung S. Chean, Rajesh Sivaprakasam, Sreekar Devarakonda, Miles W. Benjamin, James Ashcroft, Pierfrancesco Lapolla, Christin Henein, Cillian T. Forde, Mohammad Zain Sohail, Rachael J. Clegg, Zoe M. Seymour, Stavros Parasyris, Nikolaos Dimitrokallis, Benjamin J. Davies, Waleed F. A. Fahmy, Obafemi K. Wuraola, Athanasios Serlis, Binay Gurung, Andrew J. Kelly, Rishi Talwar, Paul S. Cullis, Dale J. Gracie, Markus P. Baker, George W. Cross, Wai Wai Win Mar, Raashad Hasan, Dimitri J. Pournaras, Cho Ee Ng, Ashok R. Ramasamy, Amir N. A. Iskandar, Haaris A. Shiwani, Sujesh Bansal, Stephen F. McAleer, Omar Ahmed, Umakanth R. Kempanna, John-Joe Reilly, Richard J. Davies, Sibtain Anwar, Grant A. Harris, Usama Ahmed, Kareem T. Elsanhoury, Wen Jie Chin, Nikhil Kumar Ponugoti, Javaria Faiz, Jonathon R. C. Sheen, Imran H. Yusuf, Ziyan Sheng, Grant D. Stewart, Shafquat Zaman, Aloka S. Danwaththa Liyanage, Karthikeyan P. Iyengar, Ravi Aggarwal, Setthasorn Z. Y. Ooi, Ayesha Mahmud, Mingzheng Aaron Goh, James M. D. Wheeler, Nicola J. Eardley, Michael El Boghdady, Delvene Soares, Alexander D. O'Connor, Ankur D. Kariya, Filip Fryderyk Brzeszczynski, Joshua L. Moreau, Abdel Saed, Isobel Pilkington, Devaraj M. Navaratnam, Neil A. Ryan, Hooman Soleymani Majd, Lamiese Ismail, Hemina B. Shah, Akib M. Khan, Paul C. Nankivell, Waleed Fayez Ali Fahmy, Robert W. Tyler, Leandro Siragusa, Syed S. Mannan, Giorgio Bogani, Jibran Abbasy, Piergiorgio Solli, Nadine Di Donato, Josh R. Burke, Abdul Hakeem, Firas Aljanadi, Alexander J. Baldwin, Mohamed Bekheit, Peter P. Bobak, Matyas Fehervari, Fabio Barra, Mohamed A. Thaha, Nadir Syed, James B. Olivier, Khaled A. K. Mohammed, Kate J. Williams, Tatiana Martin, Aman S. Coonar, Michael W. S. Ho, Mark W. Yao, Alexandros Konstantinos Charalabopoulos, Porfyrios G. Korompelis, Kay Anne Mak, Abdelrahman A. A. Elsayed, Eve R. Hawley, Ahmed Y. Azzam, Alan J. B. Kirk, Ahmed E. Sherif, Mostafa K. A. Hussein, James A. Blair, Yirupaiahgari K. S. Viswanath, Simon J. Cole, Dheeraj S. Attarde, Anna Y. Allan, Ioannis N. Gerogiannis, Shiva Dindyal, Muhammad H. Siddique, Saidah Sahid, Jonathan J. Neville, David N. Naumann, Matthew H. Byrne, Sean M. A. Garcia, Ali Yasen Y. Mohamedahmed, Alan A. Askari, Joerg M. Pollok, Hani J. Marcus, Kapil Sahnan, Qamar Mustafa, Ruben P. Thumbadoo, Ketan Agarwal, Sean Khedar Ramcharan, Mehran Lashari, Mostafa E. A. Abdelkarim, Toby M. Noton, Bilal H. Kirmani, Robert D. J. Whitham, Sofia Anastasiadou, Rute S. S. Castelhano, Sanad Saad, Gakul Dr Bhatta, Antonio Leyte Golpe, Rucira Ooi, Emily C. M. McKenzie, Kenneth N. Linton, Khalid M. Bhatti, Shyama S. Chadha, Liam N. Phelan, Alvaro Bedoya Ronga, Vladislav Kutuzov, Mohammed Jibreel Mohammed, Sharan H. Sambhwani, Catrin Sohrabi, Raghavan Vidya, Jaskiran K. Gill, Lisa S. Rampersad, Bincy Merin Zacharia, Waheeb A. K. Al-Azzani, Omar Pathmanaban N. Pathmanaban, Rachel Sarah Olive, Fahad S. Hossain, Jessica Harvey, Naren K. Kumaran, Annamaria Minicozzi, Andrew Neil Wheelton, Victoria A. Evans, Andrew D. Beggs, Omar M. Ismail, Chandra Shekhar Biyani, Shaikh S. Seraj, Mohammed Deputy, Eltayeb B. E. Shammeseldin, Wafi Mohammed W. M. Mohammed, Mohamed Onsa, Yizhe Lim, Ahmad Riyadh Abdulsaheb Al-Shaye, Mujahid Gasemelseed Fadlallah, Hash Al-Musawi, Umar B. J. Yousuf, Safia Zahir Ahmed, Alexandros Laios, Aliabbas Moosa, Zoe Li, Peter J. Hutchinson, Abdalla Hassan Abdalla Hassan, Shreya M. Kulkarni, Shihab A. Chowdhury, Ahmed Y. Ammar, Tarig Hassan Ahmed, Raimundas A. Lunevicius, Dimitrios Angelou, Edward J. Caruana, Panna K. Patel, Stephen J. Bromage, Panagiotis Kapsampelis, Khaled M. Sarraf, Antonios Nicolaos Athanasiou, Jai Relwani, James E. Tomlinson, Amarkumar D. Rajgor, Pedram Panahi, Rachael Collins
BRITISH JOURNAL OF SURGERY
(2023)
Article
Surgery
Dale Vimalachandran, Robert P. Jones, Ed Dickson, Jaspreet Seehra, Austin Acheson, Ewen A. Griffiths, Sivesh Kamarajah, Elaine Leung, Andrew Torrance, Christian Ottensmeier, Andrew D. Beggs, Ellen Whiteside, Helen Sanna, Danielle Bury, Esther Youd, Gareth Leopold, Matthew Pugh, Sudha Sundar, Graham S. Taylor
BRITISH JOURNAL OF SURGERY
(2023)
Meeting Abstract
Gastroenterology & Hepatology
Nabil Quraishi, Christopher Quince, Catherine Hewitt, Andrew Beggs, Konstantinos Gerasimidis, Naveen Sharma, Ye H. Oo, Peter Hawkey, Natalie J. Ives, Susan Manzoor, Nicholas Loman, Richard Hansen, Ailsa Hart, Daniel Gaya, Tariq H. Iqbal
Meeting Abstract
Gastroenterology & Hepatology
Peter Rimmer, Richard Horniblow, Jonathan Cheesbrough, Naveen Sharma, Samantha Tull, Asif Iqbal, Amanda Rossiter, Andrew Beggs, Tariq Iqbal, Mohammed Nabil Quraishi