Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

Humanized mouse models of immunological diseases and precision medicine

(2019) Leonard D. Shultz et al.   MAMMALIAN GENOME

Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy

(2019) Quynh Thu Le et al.   JNCI-Journal of the National Cancer Institute

Nasopharyngeal carcinoma

(2019) Yu-Pei Chen et al.   LANCET

Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma

(2019) Yuan Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Editorial: Combinatorial Approaches to Enhance Anti-tumor Immunity: Focus on Immune Checkpoint Blockade Therapy

(2019) Patrik Andersson et al.   Frontiers in Immunology

Characterization of PD-L1 and PD-1 Expression and CD8+ Tumor-infiltrating Lymphocyte in Epstein-Barr Virus-associated Nasopharyngeal Carcinoma

(2018) Noppadol Larbcharoensub et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Humanized Mice as Unique Tools for Human-Specific Studies

(2018) Kylie Su Mei Yong et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

CD8+ T-cell exhaustion in cancer: mechanisms and new area for cancer immunotherapy

(2018) Qi-Feng He et al.   Briefings in Functional Genomics

T Cell Dysfunction in Cancer

(2018) Daniela S. Thommen et al.   CANCER CELL

Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy

(2018) Yue Zhao et al.   GUT

Prognostic significance of tumor-infiltrating lymphocytes in nondisseminated nasopharyngeal carcinoma: A large-scale cohort study

(2018) Ya-Qin Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742)

(2018) Brigette B.Y. Ma et al.   JOURNAL OF CLINICAL ONCOLOGY

An integrated automated multispectral imaging technique that simultaneously detects and quantitates viral RNA and immune cell protein markers in fixed sections from Epstein-Barr virus-related tumours

(2018) Yu Ting Felicia Wee et al.   Annals of Diagnostic Pathology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma

(2018) Cheng-Lung Hsu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Camrelizumab (SHR-1210) alone or in combination with gemcitabine plus cisplatin for nasopharyngeal carcinoma: results from two single-arm, phase 1 trials

(2018) Wenfeng Fang et al.   LANCET ONCOLOGY

Humanized Mice for the Study of Immuno-Oncology

(2018) Philippe De La Rochere et al.   TRENDS IN IMMUNOLOGY

Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate

(2018) Kazuki Taoka et al.   Scientific Reports

Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice

(2018) Yanyan Ke et al.   JOURNAL OF VIROLOGY

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

(2018) Weitao Lin et al.   Nature Communications

Safety and Antitumor Activity of Pembrolizumab in Patients With Programmed Death-Ligand 1–Positive Nasopharyngeal Carcinoma: Results of the KEYNOTE-028 Study

(2017) Chiun Hsu et al.   JOURNAL OF CLINICAL ONCOLOGY

Epstein–Barr virus infection and nasopharyngeal carcinoma

(2017) Sai Wah Tsao et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models

(2017) William K. Decker et al.   Frontiers in Immunology

Tumor cells PD-L1 expression as a favorable prognosis factor in nasopharyngeal carcinoma patients with pre-existing intratumor-infiltrating lymphocytes

(2017) Qian Zhu et al.   OncoImmunology

Gene expression markers of Tumor Infiltrating Leukocytes

(2017) Patrick Danaher et al.   Journal for ImmunoTherapy of Cancer

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

(2016)   MOLECULES AND CELLS

Tumor CTLA-4 overexpression predicts poor survival in patients with nasopharyngeal carcinoma

(2016) Pei-Yu Huang et al.   Oncotarget

Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2R null Immunodeficient Mice

(2015) M. F. Sanmamed et al.   CANCER RESEARCH

Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection

(2015) Choong Tat Keng et al.   GUT

Erratum to: Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma

(2015) Ying Jin et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo

(2015) De-Kuan Chang et al.   Molecular Cancer

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

Human tumor infiltrating lymphocytes cooperatively regulate prostate tumor growth in a humanized mouse model

(2015) Michael D Roth et al.   Journal for ImmunoTherapy of Cancer

nCounter® PanCancer Immune Profiling Panel (NanoString Technologies, Inc., Seattle, WA)

(2015) Alessandra Cesano   Journal for ImmunoTherapy of Cancer

New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape

(2014) Deepak Mittal et al.   CURRENT OPINION IN IMMUNOLOGY

HLA-ASNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese

(2014) Yoon-Ming Chin et al.   INTERNATIONAL JOURNAL OF CANCER

Imiquimod Inhibits Melanoma Development by Promoting pDC Cytotoxic Functions and Impeding Tumor Vascularization

(2014) Caroline Aspord et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The two faces of IL-6 in the tumor microenvironment

(2014) Daniel T. Fisher et al.   SEMINARS IN IMMUNOLOGY

One mouse, one patient paradigm: New avatars of personalized cancer therapy

(2013) Prerna Malaney et al.   CANCER LETTERS

At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

(2013) Margaret K. Callahan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

GM-CSF and IL-4 Stimulate Antibody Responses in Humanized Mice by Promoting T, B, and Dendritic Cell Maturation

(2012) Q. Chen et al.   JOURNAL OF IMMUNOLOGY

Non-viral environmental risk factors for nasopharyngeal carcinoma: A systematic review

(2012) Wei-Hua Jia et al.   SEMINARS IN CANCER BIOLOGY

Bone marrow and the control of immunity

(2011) Ende Zhao et al.   Cellular & Molecular Immunology

Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways

(2010) Yi-Lan Zhang et al.   Molecular Cancer

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ in Cancer

(2008) Joan Massagué   CELL

Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinoma

(2008) Dirk P. Dittmer et al.   INTERNATIONAL JOURNAL OF CANCER