Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype

Attributes of alternatively activated (M2) macrophages

(2019) Richa Shrivastava et al.   LIFE SCIENCES

DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer.

(2019) Meghan Travers et al.   CANCER RESEARCH

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy

(2019) Vikash P. Chauhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Tumor-Associated Macrophages in Cancer

(2019) Paulina Pathria et al.   TRENDS IN IMMUNOLOGY

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

(2019) Brooke Benner et al.   Journal for ImmunoTherapy of Cancer

Cancer immunotherapy: the art of targeting the tumor immune microenvironment

(2019) Jesse Lopes da Silva et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

(2019) Chanju Lee et al.   Journal for ImmunoTherapy of Cancer

Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice

(2019) Lingyu Wei et al.   ONCOGENE

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer

(2019) Diletta Di Mitri et al.   Cell Reports

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

(2018) Degao Chen et al.   Nature Communications

Targeting VEGF/VEGFR to Modulate Antitumor Immunity

(2018) Ju Yang et al.   Frontiers in Immunology

Lactoferrin-Containing Immunocomplexes Drive the Conversion of Human Macrophages from M2- into M1-like Phenotype

(2018) Chen-Hui Gao et al.   Frontiers in Immunology

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Targeting tumor associated macrophages: The new challenge for nanomedicine

(2017) Fernando Torres Andón et al.   SEMINARS IN IMMUNOLOGY

Extraordinarily potent proinflammatory properties of lactoferrin-containing immunocomplexes against human monocytes and macrophages

(2017) Lulu Hu et al.   Scientific Reports

Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity

(2017) Karla R. Wiehagen et al.   Cancer Immunology Research

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

(2016) Mathias Wenes et al.   Cell Metabolism

Immune suppressive mechanisms in the tumor microenvironment

(2016) David H Munn et al.   CURRENT OPINION IN IMMUNOLOGY

Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe

(2015) Lulu Hu et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype

(2015) Min Liu et al.   JOURNAL OF IMMUNOLOGY

A Novel Murine Anti-Lactoferrin Monoclonal Antibody Activates Human Polymorphonuclear Leukocytes through Membrane-Bound Lactoferrin and TLR4

(2015) Xiao-Min Hu et al.   Biomed Research International

Immunomodulatory effects of lactoferrin

(2014) Tania Siqueiros-Cendón et al.   ACTA PHARMACOLOGICA SINICA

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Intravenous Immunoglobulin Promotes Antitumor Responses by Modulating Macrophage Polarization

(2014) Angeles Domínguez-Soto et al.   JOURNAL OF IMMUNOLOGY

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Anticancer effects of lactoferrin: underlying mechanisms and future trends in cancer therapy

(2014) Yunlei Zhang et al.   NUTRITION REVIEWS

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

(2014) Theerawut Chanmee et al.   Cancers

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

The role of B7 family molecules in hematologic malignancy

(2012) P. Greaves et al.   BLOOD

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-Associated Macrophages Promote Invasion while Retaining Fc-Dependent Anti-Tumor Function

(2012) K. D. Grugan et al.   JOURNAL OF IMMUNOLOGY

Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond

(2012) P. Mark Hogarth et al.   NATURE REVIEWS DRUG DISCOVERY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility

(2010) G. Solinas et al.   JOURNAL OF IMMUNOLOGY

Production of immune-modulatory nonclassical molecules HLA-G and HLA-E by tumor infiltrating ameboid microglia/macrophages in glioblastomas: A role in innate immunity?

(2010) Leos Kren et al.   JOURNAL OF NEUROIMMUNOLOGY

In vivo veritas: the surprising roles of Fc receptors in immunity

(2010) Jeffrey Ravetch   NATURE IMMUNOLOGY

Lactoferrin modulation of BCG-infected dendritic cell functions

(2009) S.-A. Hwang et al.   INTERNATIONAL IMMUNOLOGY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Influence of bovine lactoferrin on expression of presentation molecules on BCG-infected bone marrow derived macrophages

(2008) S HWANG et al.   BIOCHIMIE

Lactoferrin: structure, function and applications

(2008) Susana A. González-Chávez et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark