C reactive protein impairs adaptive immunity in immune cells of patients with melanoma

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

(2018) Margherita Norelli et al.   NATURE MEDICINE

Association of preoperative serum CRP with PD-L1 expression in 508 patients with non-small cell lung cancer: A comprehensive analysis of systemic inflammatory markers

(2018) Takaki Akamine et al.   SURGICAL ONCOLOGY-OXFORD

C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance

(2018) Rachel V. Jimenez et al.   Frontiers in Immunology

Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes

(2018) James D. McFadyen et al.   Frontiers in Immunology

CCL1 is a major regulatory T cell attracting factor in human breast cancer

(2018) Benjamin Kuehnemuth et al.   BMC CANCER

Baseline and postoperative C-reactive protein levels predict mortality in operable lung cancer

(2017) Ugo Pastorino et al.   EUROPEAN JOURNAL OF CANCER

Early response of C-reactive protein as a predictor of survival in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors

(2017) Yosuke Yasuda et al.   International Journal of Clinical Oncology

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

(2017) Paul M Ridker et al.   LANCET

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

C-reactive protein promotes bone destruction in human myeloma through the CD32–p38 MAPK–Twist axis

(2017) Jing Yang et al.   Science Signaling

Predictive clinical parameters for the response of nivolumab in pretreated advanced non-small-cell lung cancer

(2017) Yuko Oya et al.   Oncotarget

C-reactive protein promotes bone destruction in human myeloma through the CD32–p38 MAPK–Twist axis

(2017) Jing Yang et al.   Science Signaling

A Serum Protein Signature Associated with Outcome after Anti–PD-1 Therapy in Metastatic Melanoma

(2017) Jeffrey S. Weber et al.   Cancer Immunology Research

Pretreatment C-reactive protein to albumin ratio for predicting overall survival in advanced pancreatic cancer patients

(2017) Junjie Hang et al.   Scientific Reports

Biomarkers of inflammation and breast cancer risk: a case-control study nested in the EPIC-Varese cohort

(2017) Claudia Agnoli et al.   Scientific Reports

Toxicities of chimeric antigen receptor T cells: recognition and management

(2016) Jennifer N. Brudno et al.   BLOOD

Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn’s disease: a case report

(2016) Marc Uemura et al.   Journal of Hematology & Oncology

Sequential administration of nivolumab and ipilimumab with a planned switch in patients with advanced melanoma (CheckMate 064): an open-label, randomised, phase 2 trial

(2016) Jeffrey S Weber et al.   LANCET ONCOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

(2016) D. T. Teachey et al.   Cancer Discovery

Interleukin-6 as a Therapeutic Target

(2015) J.-F. Rossi et al.   CLINICAL CANCER RESEARCH

C-Reactive Protein As a Marker of Melanoma Progression

(2015) Shenying Fang et al.   JOURNAL OF CLINICAL ONCOLOGY

C-Reactive Protein Directly Suppresses Th1 Cell Differentiation and Alleviates Experimental Autoimmune Encephalomyelitis

(2015) Lin Zhang et al.   JOURNAL OF IMMUNOLOGY

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Safety and Efficacy of Combination Immunotherapy With Interferon Alfa-2b and Tremelimumab in Patients With Stage IV Melanoma

(2011) Ahmad A. Tarhini et al.   JOURNAL OF CLINICAL ONCOLOGY

Review: Soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

(2010) Michael L. Litvack et al.   Innate Immunity

Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses

(2009) Yun Lin et al.   CYTOTHERAPY

Serum Amyloid A As a Prognostic Marker in Melanoma Identified by Proteomic Profiling

(2009) Peter Findeisen et al.   JOURNAL OF CLINICAL ONCOLOGY

Structural recognition and functional activation of FcγR by innate pentraxins

(2008) Jinghua Lu et al.   NATURE