Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway

Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis

(2019) Jinbeom Heo et al.   EMBO Molecular Medicine

Ascorbic Acid 2-Glucoside Stably Promotes the Primitiveness of Embryonic and Mesenchymal Stem Cells Through Ten–Eleven Translocation- and cAMP-Responsive Element-Binding Protein-1-Dependent Mechanisms

(2019) Seungun Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy

(2018) Bruce R. Blazar et al.   BLOOD

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

(2018) Jacques Galipeau et al.   Cell Stem Cell

Small hypoxia-primed mesenchymal stem cells attenuate graft-versus-host disease

(2018) YongHwan Kim et al.   LEUKEMIA

Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function

(2018) Eui Man Jeong et al.   Stem Cell Reports

Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells

(2017) Jisun Lim et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Cytokine mediators of chronic graft-versus-host disease

(2017) Kelli P.A. MacDonald et al.   JOURNAL OF CLINICAL INVESTIGATION

Perspectives on Manufacturing of High-Quality Cell Therapies

(2017) Isabelle Rivière et al.   MOLECULAR THERAPY

Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

(2017) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets

(2017) Robert Zeiser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sirt1 Regulates DNA Methylation and Differentiation Potential of Embryonic Stem Cells by Antagonizing Dnmt3l

(2017) Jinbeom Heo et al.   Cell Reports

Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation

(2017) Federico Simonetta et al.   Frontiers in Immunology

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Association of Cumulative Steroid Dose with Risk of Infection after Treatment for Severe Acute Graft-versus-Host Disease

(2016) Yayoi Matsumura-Kimoto et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Phase II Multicenter, Randomized, Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord–Derived Mesenchymal Stromal Cells in the Prophylaxis of Chronic Graft-Versus-Host Disease After HLA-Haploidentical Stem-Cell Transplantation

(2016) Lei Gao et al.   JOURNAL OF CLINICAL ONCOLOGY

Novel targets in the treatment of chronic graft-versus-host disease

(2016) A Im et al.   LEUKEMIA

Oligodendrocyte precursors migrate along vasculature in the developing nervous system

(2016) H.-H. Tsai et al.   SCIENCE

Protein Kinase A Signaling Is Inhibitory for Reprogramming into Pluripotent Stem Cells

(2016) Jong Soo Kim et al.   STEM CELLS AND DEVELOPMENT

The Free Radical Scavenger NecroX-7 Attenuates Acute Graft-versus-Host Disease via Reciprocal Regulation of Th1/Regulatory T Cells and Inhibition of HMGB1 Release

(2015) Keon-Il Im et al.   JOURNAL OF IMMUNOLOGY

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

(2015) Galbha Duggal et al.   STEM CELLS

A Porous Membrane-Mediated Isolation of Mesenchymal Stem Cells from Human Embryonic Stem Cells

(2015) Ki-Sung Hong et al.   TISSUE ENGINEERING PART C-METHODS

New Strategies for Overcoming Limitations of Mesenchymal Stem Cell-Based Immune Modulation

(2015) Nayoun Kim et al.   International Journal of Stem Cells

Optimization of the therapeutic efficacy of human umbilical cord blood–mesenchymal stromal cells in an NSG mouse xenograft model of graft-versus-host disease

(2014) Yun Kyung Jang et al.   CYTOTHERAPY

Thiol/Redox Metabolomic Profiling Implicates GSH Dysregulation in Early Experimental Graft versus Host Disease (GVHD)

(2014) Jung H. Suh et al.   PLoS One

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Fasting Induces Nuclear Factor E2-Related Factor 2 and ATP-Binding Cassette Transporters via Protein Kinase A and Sirtuin-1 in Mouse and Human

(2013) Supriya R. Kulkarni et al.   ANTIOXIDANTS & REDOX SIGNALING

A Coumarin-based Fluorescence Sensor for the Reversible Detection of Thiols

(2012) A Young Cho et al.   CHEMISTRY LETTERS

Influence of immunosuppressive treatment on risk of recurrent malignancy after allogeneic hematopoietic cell transplantation

(2011) Y. Inamoto et al.   BLOOD

Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease

(2011) E. Gatza et al.   Science Translational Medicine

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Mesenchymal stem cell as salvage treatment for refractory chronic GVHD

(2010) J Y Weng et al.   BONE MARROW TRANSPLANTATION

CRTC3 links catecholamine signalling to energy balance

(2010) Youngsup Song et al.   NATURE

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutathione: A key player in autoimmunity

(2009) Carlo Perricone et al.   AUTOIMMUNITY REVIEWS

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

α-Melanocyte-Stimulating Hormone Counteracts the Suppressive Effect of UVB on Nrf2 and Nrf-Dependent Gene Expression in Human Skin

(2009) Agatha Kokot et al.   ENDOCRINOLOGY