Neuroprotective effects of FK866 against traumatic brain injury: Involvement of p38/ERK pathway

Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets

(2019) Si Yun Ng et al.   Frontiers in Cellular Neuroscience

Regionally clusteredABCC8polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury

(2018) Ruchira Menka Jha et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

(2017) Andrew I R Maas et al.   LANCET NEUROLOGY

NAMPT inhibitor protects ischemic neuronal injury in rat brain via anti-neuroinflammation

(2017) Chen-Xiang Chen et al.   NEUROSCIENCE

Extracellular NAMPT/Visfatin induces proliferation through ERK1/2 and AKT and inhibits apoptosis in breast cancer cells

(2017) Zafar Gholinejad et al.   PEPTIDES

Cellular microparticles and pathophysiology of traumatic brain injury

(2017) Zilong Zhao et al.   Protein & Cell

Metabolic, enzymatic and gene involvement in cerebral glucose dysmetabolism after traumatic brain injury

(2016) Angela Maria Amorini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Melatonin attenuates neuronal apoptosis through up-regulation of K+-Cl−cotransporter KCC2 expression following traumatic brain injury in rats

(2016) Haijian Wu et al.   JOURNAL OF PINEAL RESEARCH

Cerebral Edema in Traumatic Brain Injury

(2016) Ethan A. Winkler et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages

(2015) Bente Halvorsen et al.   ATHEROSCLEROSIS

The contribution of astrocytes and microglia to traumatic brain injury

(2015) Ila P Karve et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening

(2015) Venkat K. Pulla et al.   Chemical Biology & Drug Design

Chloroquine exerts neuroprotection following traumatic brain injury via suppression of inflammation and neuronal autophagic death

(2015) CHANG-MENG CUI et al.   Molecular Medicine Reports

Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury

(2015) Rajaneesh K. Gupta et al.   MOLECULAR NEUROBIOLOGY

Minocycline Protects Against NLRP3 Inflammasome-Induced Inflammation and P53-Associated Apoptosis in Early Brain Injury After Subarachnoid Hemorrhage

(2015) Jianru Li et al.   MOLECULAR NEUROBIOLOGY

Cytotoxic and vasogenic cerebral oedema in traumatic brain injury: Assessment with FLAIR and DWI imaging

(2014) Anne M. Hudak et al.   BRAIN INJURY

On-Target Effect of FK866, a Nicotinamide Phosphoribosyl Transferase Inhibitor, by Apoptosis-Mediated Death in Chronic Lymphocytic Leukemia Cells

(2014) I. Gehrke et al.   CLINICAL CANCER RESEARCH

Depletion of the Central Metabolite NAD Leads to Oncosis-mediated Cell Death

(2014) Christopher Del Nagro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of NF-κB Mediates Astrocyte Swelling and Brain Edema in Traumatic Brain Injury

(2014) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROTRAUMA

Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis

(2014) Marie-Charlotte Laiguillon et al.   ARTHRITIS RESEARCH & THERAPY

FK866, a Visfatin Inhibitor, Protects Against Acute Lung Injury After Intestinal Ischemia–Reperfusion in Mice via NF-κB Pathway

(2013) Akihisa Matsuda et al.   ANNALS OF SURGERY

Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis

(2013) Jessy Présumey et al.   ANNALS OF THE RHEUMATIC DISEASES

Foxo3a Transcriptionally Upregulates AQP4 and Induces Cerebral Edema Following Traumatic Brain Injury

(2013) S. Kapoor et al.   JOURNAL OF NEUROSCIENCE

Immediate splenectomy down-regulates the MAPK–NF-κB signaling pathway in rat brain after severe traumatic brain injury

(2013) Weihua Chu et al.   Journal of Trauma and Acute Care Surgery

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

(2012) Emanuela Esposito et al.   Journal of Neuroinflammation

Protective Effects of mGluR5 Positive Modulators Against Traumatic Neuronal Injury Through PKC-Dependent Activation of MEK/ERK Pathway

(2012) Tao Chen et al.   NEUROCHEMICAL RESEARCH

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY