Synthetic and External Controls in Clinical Trials – A Primer for Researchers

The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm

(2019) Viswanathan Mohan et al.   Diabetes Therapy

Roche pays $1.9 billion for Flatiron's army of electronic health record curators

(2018) Justin Petrone   NATURE BIOTECHNOLOGY

A review of NICE appraisals of pharmaceuticals 2000-2016 found variation in establishing comparative clinical effectiveness

(2018) Michael Anderson et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Is the concept of clinical equipoise still relevant to research?

(2017) Spencer Phillips Hey et al.   BMJ-British Medical Journal

Is the concept of clinical equipoise still relevant to research?

(2017) Spencer Phillips Hey et al.   BMJ-British Medical Journal

No rationale for 1 variable per 10 events criterion for binary logistic regression analysis

(2016) Maarten van Smeden et al.   BMC Medical Research Methodology

Changing clinical patterns in rheumatoid arthritis management over two decades: sequential observational studies

(2016) Aneela N Mian et al.   BMC MUSCULOSKELETAL DISORDERS

Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia

(2016) N Gökbuget et al.   Blood Cancer Journal

Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration

(2015) Karel G.M. Moons et al.   ANNALS OF INTERNAL MEDICINE

Quantum of Effectiveness Evidence in FDA’s Approval of Orphan Drugs

(2015) Frank J. Sasinowski et al.   Therapeutic Innovation & Regulatory Science

Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies: The CHARMS Checklist

(2014) Karel G. M. Moons et al.   PLOS MEDICINE

Making inferences on treatment effects from real world data: propensity scores, confounding by indication, and other perils for the unwary in observational research

(2013) N. Freemantle et al.   BMJ-British Medical Journal

The prognostic value of baseline CD4+ cell count beyond 6 months of antiretroviral therapy in HIV-positive patients in a resource-limited setting

(2012) Edward J. Mills et al.   AIDS

Orphan drugs, orphan diseases. The first decade of orphan drug legislation in the EU

(2012) Roberta Joppi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

State-Transition Modeling: A Report of the ISPOR-SMDM Modeling Good Research Practices Task Force-3

(2012) Uwe Siebert et al.   VALUE IN HEALTH

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

(2011) Gordon Guyatt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Propensity scores: From naïve enthusiasm to intuitive understanding

(2011) Elizabeth Williamson et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER