Article
Chemistry, Applied
Benjamin P. Westberry, Bradley W. Mansel, Timothy M. Ryan, Leif Lundin, M. A. K. Williams
Summary: The traditional notion that.-carrageenan exists in solution as a random coil has been challenged by new research, which shows that the solution-state structure of.-carrageenan retains the helical motifs present in the solid-state. Additionally, there is no evidence to suggest that single chains undergo any conformational transition upon the addition of ions.
CARBOHYDRATE POLYMERS
(2022)
Article
Materials Science, Multidisciplinary
Jiacheng Ge, Peng Luo, Zhenduo Wu, Wentao Zhang, Sinan Liu, Si Lan, Jonathan D. Almer, Yang Ren, Xun-Li Wang, Weihua Wang
Summary: Studying the flow behavior of amorphous solids is crucial for understanding their deformation mechanism, but detecting basic flow events in these materials is challenging. Using simultaneous SAXS/WAXS experiments, researchers have identified elementary flow carriers in wound metallic glasses, with a radius of gyration ranging from 2.5 to 3.5 nm, based on flow-induced structural heterogeneities. The size of these carriers increases and their morphology changes from spherical to rod-like during flow. Additionally, the atomic structure undergoes an unusual change to a more disordered state during winding/annealing at a temperature around 0.8 Tg. This work provides an atomic-to-nanoscale description of flow carriers in amorphous solids during deformation.
MATERIALS RESEARCH LETTERS
(2023)
Article
Chemistry, Physical
Xinyi Liu, Shao-Chun Lee, Soenke Seifer, Randall E. Winans, Lei Cheng, Y. Z, Tao Li
Summary: In this study, the solvation structures of a series of imide-based lithium salt aqueous solutions were investigated using SAXS/WAXS and MD simulation techniques. Two competing structures were found, and the anion network played a crucial role in obtaining a stable and enlarged electrochemical window.
ENERGY STORAGE MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Uri Raviv, Roi Asor, Asaf Shemesh, Avi Ginsburg, Tal Ben-Nun, Yaelle Schilt, Yehonatan Levartovsky, Israel Ringel
Summary: The current challenges of structural biophysics include determining the structure of large self-assembled complexes, resolving the structure of ensembles of complex structures, and unraveling the dynamic pathways and mechanisms leading to the formation of complex structures from their subunits. Modern solution X-ray scattering data provide high-spatial and high-temporal structural data that can address these challenges. However, analyzing solution scattering data is challenging, and various analysis tools have been developed.
JOURNAL OF STRUCTURAL BIOLOGY
(2023)
Article
Chemistry, Applied
Benjamin P. Westberry, Bradley W. Mansel, Leif Lundin, M. A. K. Williams
Summary: Recently, molecular dynamics simulations and solution-state x-ray scattering experiments have shown that ir-carrageenan chains have a helical structure even in aqueous solution. The addition of ions to single chains does not result in conformational transitions. Further simulations using pairs of ir-carrageenan chains in 0.1 M NaI solutions confirm the formation of double helices during the disorder-to-order transition.
CARBOHYDRATE POLYMERS
(2023)
Article
Pharmacology & Pharmacy
Antonio Lipa-Castro, Francois-Xavier Legrand, Gillian Barratt
Summary: Cochleate systems formed from phospholipids have useful sustained release capabilities, improving bioavailability and reducing toxicity. There are various methods available for preparing cochleates, as well as techniques for characterization, ranging from simple to more sophisticated ones. These features of cochleate systems can guide formulators in choosing suitable methods for their needs in terms of time, precision, and technological difficulty.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Jiahui Chen, Olaf J. Borkiewicz, Alexander V. Grishaev, Fan Zhang, Mrinal K. Bera, Uta Ruett, Igor Levin
Summary: We propose a method for high-resolution structural characterization of biomacromolecules in aqueous solution using X-ray scattering experiments with an extended range of scattering vectors (q). This method allows the recovery of the atomic pair distribution function and facilitates structure determination. We demonstrate the potential of this method by studying cyclodextrins (CD) as model systems and successfully identifying deviations in the tilting angles of glycosidic units. Our results highlight the need for further exploration of ultra-wide-angle X-ray scattering measurements for biomacromolecules.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Lisa Thomson, Daniel McDowall, Libby Marshall, Olivia Marshall, Henry Ng, W. Joseph A. Homer, Dipankar Ghosh, Wanli Liu, Adam M. Squires, Eirini Theodosiou, Paul D. Topham, Louise C. Serpell, Robert J. Poole, Annela Seddon, Dave J. Adams
Summary: This study demonstrates the treatment of a simple dipeptide building block as a polyelectrolyte and the use of polymer physics approaches to explain self-assembly, leading to the preparation of interesting materials.
Article
Polymer Science
Yunwei Wang, Li Li, Yiming Wang, Qingsong Yang, Zhishuang Ye, Liang Sun, Fan Yang, Xuhong Guo
Summary: The study systematically investigated the effect of counterions on interactions among SPB particles, revealing the mechanisms of counterions on the interactions and local ordered structure among PAA chains in concentrated SPBs by combining SAXS, WAXS, and rheology techniques.
Review
Chemistry, Physical
Jizhen Zhang, Ken Aldren S. Usman, Mia Angela N. Judicpa, Dylan Hegh, Peter A. Lynch, Joselito M. Razal
Summary: X-rays are a type of high-energy electromagnetic radiation that can penetrate objects with wavelengths ranging from 10 picometers to 10 nanometers. They offer a powerful tool for studying the atomic and elemental information of objects, similar to visible light. This review summarizes the recent progress of using X-ray-based characterization methods in MXenes, a new family of 2D nanomaterials. These methods provide important information on synthesis, elemental composition, and the assembly of MXene sheets and their composites, and new characterization methods are proposed for future research directions.
Article
Biochemistry & Molecular Biology
Kevin Pounot, Giorgio Schiro, Matteo Levantino
Summary: Relevant events during protein function, such as ligand binding/release and interaction with substrates or light, often involve out-of-equilibrium structural dynamics. Time-resolved experimental techniques have been developed to track protein structural changes in real time after a reaction-triggering event. Time-resolved X-ray solution scattering is a promising approach that offers both structural sensitivity and temporal resolution in the femto-to-millisecond time range. This article presents the basic principles of the technique, describes recent relevant results, and discusses computational methods for interpreting time-resolved X-ray solution scattering data.
CURRENT OPINION IN STRUCTURAL BIOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Alexis Cherri, Ilias Iliopoulos, Gilles Regnier, Benoit Brule, Guillaume Le, Sylvie Tence-Girault
Summary: This study focuses on the isothermal crystallization process of a specific member of the PEKK family, PEKK 50/50, and demonstrates its potential for HT-LS manufacturing at high temperatures (approximately 280-290 degrees C) through experimental evidence.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Obaid Iqbal, Jean Claude Habumugisha, Shengyao Feng, Yuanfei Lin, Wei Chen, Wancheng Yu, Liangbin Li
Summary: The microstructural origins of the double yield points of metallocene linear low-density polyethylene (mLLDPE) precursor films were found to be highly related to the initial orientation of the original precursor film, with different orientations leading to different microstructural origins at the first yield point, but all precursor films undergo melting-recrystallization and the formation of the fibrillary structure beyond the second yield point.
Article
Materials Science, Multidisciplinary
Kakeru Obayashi, Kazutaka Kamitani, Chien-Wei Chu, Ryosuke Kawatoko, Chao-Hung Cheng, Atsushi Takahara, Ken Kojio
Summary: The internal structure of polyurethane adhesive undergoes changes during lap shear deformation, with an increase in the spacing of hard segment domains and the merging of tilt angle with the stretching direction. These findings are of great significance for the practical design of adhesives.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Paper & Wood
Claudia Vicente Esteves, Elisabet Brannvall, Jasna S. Stevanic, Per Tomas Larsson
Summary: The effect of kraft cooking, oxygen delignification, and refining on the softwood fiber wall nanostructure was evaluated using X-ray scattering. Kraft delignification was found to have a major influence on the fiber nanostructure modification, while oxygen delignification had little impact. Particle sizes were more stable compared to cavity sizes, and there were no significant differences among different delignification processes or refining degrees.
Article
Instruments & Instrumentation
Masafumi Fukuto, Lin Yang, Dmytro Nykypanchuk, Ivan Kuzmenko
JOURNAL OF SYNCHROTRON RADIATION
(2016)
Article
Chemistry, Physical
Lingshuang Song, Lin Yang, Jie Meng, Sichun Yang
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2017)
Article
Chemistry, Multidisciplinary
Vito Graziano, Lisa Miller, Lin Yang
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2018)
Article
Endocrinology & Metabolism
Alvin S. Acerbo, Andrea T. Kwaczala, Lin Yang, Stefan Judex, Lisa M. Miller
CALCIFIED TISSUE INTERNATIONAL
(2014)
Article
Biochemistry & Molecular Biology
Aleksandr Sverzhinsky, Shuo Qian, Lin Yang, Marc Allaire, Isabel Moraes, Dewang Ma, Jacqueline W. Chung, Manuela Zoonens, Jean-Luc Popot, James W. Coulton
JOURNAL OF MEMBRANE BIOLOGY
(2014)
Article
Instruments & Instrumentation
Lin Yang
JOURNAL OF SYNCHROTRON RADIATION
(2013)
Article
Multidisciplinary Sciences
Hideyo Inouye, Yan Zhang, Lin Yang, Nagarajan Venugopalan, Robert F. Fischetti, S. Charlotte Gleber, Stefan Vogt, W. Fowle, Bryan Makowski, Melvin Tucker, Peter Ciesielski, Bryon Donohoe, James Matthews, Michael E. Himmel, Lee Makowski
SCIENTIFIC REPORTS
(2014)
Article
Multidisciplinary Sciences
Maruti Hegde, Lin Yang, Francesco Vita, Ryan J. Fox, Renee van de Watering, Ben Norder, Ugo Lafont, Oriano Francescangeli, Louis A. Madsen, Stephen J. Picken, Edward T. Samulski, Theo J. Dingemans
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Jae-Hyun Cho, Baoyu Zhao, Jie Shi, Nowlan Savage, Qingliang Shen, James Byrnes, Lin Yang, Wonmuk Hwang, Pingwei Li
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Article
Biochemistry & Molecular Biology
Catherine Cheu, Lin Yang, Mu-Ping Nieh
CHEMISTRY AND PHYSICS OF LIPIDS
(2020)
Article
Instruments & Instrumentation
Lin Yang, Edwin Lazo, James Byrnes, Shirish Chodankar, Stephen Antonelli, Maksim Rakitin
Summary: During the COVID-19 pandemic, the Life Science X-ray Scattering (LiX) beamline developed new instrumentation and mail-in protocols to overcome the access barrier to solution scattering measurements. Efforts were made to utilize existing instrumentation and align with the larger support for remote measurements at NSLS-II. Additional software tools were developed to ensure data quality, automate adjustments in data processing, and provide initial data assessment summaries for mail-in measurements where staff-user interaction is limited.
JOURNAL OF SYNCHROTRON RADIATION
(2021)
Article
Instruments & Instrumentation
Lin Yang, Jiliang Liu, Shirish Chodankar, Stephen Antonelli, Jonathan DiFabio
Summary: This work introduces the instrumentation and software used for microbeam scattering and structural mapping at the Life Science X-ray Scattering beamline at NSLS-II. The adjustable beam size and simultaneous collection of scattering data at small and wide angles are achieved using a two-stage focusing scheme and multiple Pilatus detectors. Fly scans are implemented to minimize time interval between scattering patterns, and an in-vacuum sample environment is developed to reduce background scattering. The processing of data involves quantifying features from reciprocal coordinates and constructing structural maps. The paper presents examples of mapping onion epidermal cell walls and tomographic sectioning of an intact poplar stem.
JOURNAL OF SYNCHROTRON RADIATION
(2022)
Article
Chemistry, Physical
Chung-Hao Liu, Catherine Cheu, John G. Barker, Lin Yang, Mu-Ping Nieh
Summary: A well-defined discoidal bicelle composed of three lipids, DPPC, DHPC, and DPPG, can serve as a generalized template for the synthesis of hydrophobic polymer nano-rings. Styrene monomers migrate to the rim region during polymerization, forming well-defined nano-rings. This facile synthesis method is applicable to various hydrophobic monomers, and the nano-rings have a large interfacial area, making them potential building blocks for functional materials.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Prakash Nepal, Abdullah Al Bashit, Lin Yang, Lee Makowski
Summary: This article discusses the challenges and strategies of extracting information from fibrils using SAXS. By using micro- and nano-beams, scattering from very small volumes can be measured. The correlations between the positions of fibrils and other constituents have a significant impact on the observed scattering. A method to compute the spatial correlation function of the fibril in the direction perpendicular to the fibril axis is proposed, providing information about the fibril structure and tissue organization.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2022)
