Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: the first multicentre, phase III trial in China

Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke

(2015) Bart M. Demaerschalk et al.   STROKE

Safety and Efficacy of Intravenous Recombinant Tissue Plasminogen Activator Administered in the 3- to 4.5-hour Window in Korea

(2014) Tai Hwan Park et al.   Journal of Stroke & Cerebrovascular Diseases

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

Feasibility and outcomes of intravenous thrombolysis 3–4.5hours after stroke in Chinese patients

(2013) Zhi-Peng Xu et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Guidelines for the Early Management of Patients With Acute Ischemic Stroke

(2013) Edward C. Jauch et al.   STROKE

Results of Intravenous Thrombolysis Within 4.5 to 6 Hours and Updated Results Within 3 to 4.5 Hours of Onset of Acute Ischemic Stroke Recorded in the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis Register (SITS-ISTR)

(2013) Niaz Ahmed   JAMA Neurology

Implementation and Outcome of Thrombolysis with Alteplase 3 to 4.5 h After Acute Stroke in Chinese Patients

(2012) Xiao-Ling Liao et al.   CNS Neuroscience & Therapeutics

Thrombolysis for Acute Ischaemic Stroke with Alteplase in an Asian Population: Results of the Multicenter, Multinational Safe Implementation of Thrombolysis in Stroke-Non-European Union World (SITS-NEW)

(2012) Joung-Ho Rha et al.   International Journal of Stroke

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

(2010) Kennedy R Lees et al.   LANCET

Implementation and outcome of thrombolysis with alteplase 3–4·5 h after an acute stroke: an updated analysis from SITS-ISTR

(2010) Niaz Ahmed et al.   LANCET NEUROLOGY

Stroke treatment with alteplase given 3·0–4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial

(2009) Erich Bluhmki et al.   LANCET NEUROLOGY

Efficacy and Safety of Tissue Plasminogen Activator 3 to 4.5 Hours After Acute Ischemic Stroke

(2009) Maarten G. Lansberg et al.   STROKE

Thrombolysis with alteplase 3–4·5 h after acute ischaemic stroke (SITS-ISTR): an observational study

(2008) Nils Wahlgren et al.   LANCET

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE