Clinical and Imaging Markers of Prodromal Parkinson's Disease

The Parkinsonian Personality: More Than Just a “Trait”

(2019) Antonina Luca et al.   Frontiers in Neurology

The Combination of DAT-SPECT, Structural and Diffusion MRI Predicts Clinical Progression in Parkinson’s Disease

(2019) Sara Lorio et al.   Frontiers in Aging Neuroscience

Prodromal Parkinson's Disease: The Decade Past, the Decade to Come

(2019) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Predicting diagnosis of Parkinson's disease: A risk algorithm based on primary care presentations

(2019) Anette Schrag et al.   MOVEMENT DISORDERS

Hyposmia as a Predictive Marker of Parkinson’s Disease: A Systematic Review and Meta-Analysis

(2019) Xin Sui et al.   Biomed Research International

Erectile Dysfunction Preceding Clinically Diagnosed α-Synucleinopathies: A Case-Control Study in Olmsted County

(2019) Shemonti Hasan et al.   Parkinsons Disease

Longitudinal analyses of cerebrospinal fluid α‐Synuclein in prodromal and early Parkinson's disease

(2019) Brit Mollenhauer et al.   MOVEMENT DISORDERS

What Have We Learned from Cerebrospinal Fluid Studies about Biomarkers for Detecting LRRK2 Parkinson’s Disease Patients and Healthy Subjects with Parkinson’s-Associated LRRK2 Mutations?

(2019) David A. Loeffler et al.   Journal of Parkinsons Disease

Sleep Disturbance as Potential Risk and Progression Factor for Parkinson’s Disease

(2019) Nicolaas I. Bohnen et al.   Journal of Parkinsons Disease

Severe Constipation in Parkinson's Disease and in Parkinsonisms: Prevalence and Affecting Factors

(2019) Giuseppe Frazzitta et al.   Frontiers in Neurology

Update of the MDS research criteria for prodromal Parkinson's disease

(2019) Sebastian Heinzel et al.   MOVEMENT DISORDERS

Functional Connectivity Signatures of Parkinson’s Disease

(2019) Alessandro Tessitore et al.   Journal of Parkinsons Disease

CSF or serum neurofilament light added to α‐Synuclein panel discriminates Parkinson's from controls

(2019) Linda P. Oosterveld et al.   MOVEMENT DISORDERS

Physical activity and prodromal features of Parkinson disease

(2019) Katherine C. Hughes et al.   NEUROLOGY

REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)

(2018) Po-Chi Chan et al.   BEHAVIOURAL NEUROLOGY

The accuracy of the clinical diagnosis of Parkinson disease. The HUNT study

(2018) Eldbjørg Hustad et al.   JOURNAL OF NEUROLOGY

The effect of LRRK2 mutations on the cholinergic system in manifest and premanifest stages of Parkinson's disease: a cross-sectional PET study

(2018) Shu-Ying Liu et al.   LANCET NEUROLOGY

In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study

(2018) Karoline Knudsen et al.   LANCET NEUROLOGY

Application of the Movement Disorder Society prodromal criteria in healthy G2019S -LRRK2 carriers

(2018) Anat Mirelman et al.   MOVEMENT DISORDERS

Age- and sex-related heterogeneity in prodromal Parkinson's disease

(2018) Sebastian Heinzel et al.   MOVEMENT DISORDERS

Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease

(2018) C. Ruffmann et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease

(2018) Marthe Gurine Førland et al.   PARKINSONISM & RELATED DISORDERS

Loss of Substantia Nigra Hyperintensity at 3.0-T MR Imaging in Idiopathic REM Sleep Behavior Disorder: Comparison with 123I-FP-CIT SPECT

(2018) Yun Jung Bae et al.   RADIOLOGY

When Do α-Synucleinopathies Start? An Epidemiological Timeline

(2018) Rodolfo Savica et al.   JAMA Neurology

Accuracy of Rating Scales and Clinical Measures for Screening of Rapid Eye Movement Sleep Behavior Disorder and for Predicting Conversion to Parkinson’s Disease and Other Synucleinopathies

(2018) Matej Skorvanek et al.   Frontiers in Neurology

Diagnostic biomarkers for Parkinson’s disease at a glance: where are we?

(2018) Ilaria Cova et al.   JOURNAL OF NEURAL TRANSMISSION

Orthostatic Hypotension as a Prodromal Marker of α-Synucleinopathies

(2018) Jose-Alberto Palma et al.   JAMA Neurology

The prodromes of Parkinson's disease

(2018) Richard Nathaniel Rees et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Recent Advances in Biomarkers for Parkinson’s Disease

(2018) Runcheng He et al.   Frontiers in Aging Neuroscience

From Prodromal to Overt Parkinson’s Disease: Towards a New Definition in the Year 2040

(2018) Daniela Berg et al.   Journal of Parkinsons Disease

Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison

(2018) Susanna Jakobson Mo et al.   EJNMMI Research

Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies

(2017) Daryl J Wile et al.   LANCET NEUROLOGY

Cognition and the course of prodromal Parkinson's disease

(2017) Daniel Weintraub et al.   MOVEMENT DISORDERS

Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings

(2017) Charles H. Adler et al.   MOVEMENT DISORDERS

Application of the movement disorder society prodromal Parkinson's disease research criteria in 2 independent prospective cohorts

(2017) Andrea Pilotto et al.   MOVEMENT DISORDERS

Validation of the MDS research criteria for prodromal Parkinson's disease: Longitudinal assessment in a REM sleep behavior disorder (RBD) cohort

(2017) Seyed-Mohammad Fereshtehnejad et al.   MOVEMENT DISORDERS

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

Non-motor features of Parkinson disease

(2017) Anthony H.V. Schapira et al.   NATURE REVIEWS NEUROSCIENCE

Prospective clinical and DaT-SPECT imaging in premotor LRRK2 G2019S-associated Parkinson disease

(2017) María Sierra et al.   NEUROLOGY

Skin nerve phosphorylated α-synuclein deposits in idiopathic REM sleep behavior disorder

(2017) Elena Antelmi et al.   NEUROLOGY

Structural connectome alterations in prodromal and de novo Parkinson's disease patients

(2017) Ming-Ching Wen et al.   PARKINSONISM & RELATED DISORDERS

Association Between Poor Cognitive Functioning and Risk of Incident Parkinsonism

(2017) Sirwan K. L. Darweesh et al.   JAMA Neurology

Neuroimaging in pre-motor Parkinson's disease

(2017) Thomas R. Barber et al.   NeuroImage-Clinical

Alterations in striato-thalamo-pallidal intrinsic functional connectivity as a prodrome of Parkinson's disease

(2017) Eran Dayan et al.   NeuroImage-Clinical

DaT-SPECT assessment depicts dopamine depletion among asymptomatic G2019S LRRK2 mutation carriers

(2017) Moran Artzi et al.   PLoS One

Constipation: an emerging risk factor for Parkinson's disease?

(2016) P. Stirpe et al.   EUROPEAN JOURNAL OF NEUROLOGY

The prediagnostic phase of Parkinson's disease

(2016) Alastair John Noyce et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Assessment of α-synuclein in submandibular glands of patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study

(2016) Dolores Vilas et al.   LANCET NEUROLOGY

Prodromal Parkinson's disease as defined per MDS research criteria in the general elderly community

(2016) Philipp Mahlknecht et al.   MOVEMENT DISORDERS

Constipation in parkinson's disease: Subjective symptoms, objective markers, and new perspectives

(2016) Karoline Knudsen et al.   MOVEMENT DISORDERS

Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson's Disease

(2016) Sara Hall et al.   MOVEMENT DISORDERS

Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression

(2016) Nour K. Majbour et al.   MOVEMENT DISORDERS

Advances in markers of prodromal Parkinson disease

(2016) Ronald B. Postuma et al.   Nature Reviews Neurology

Prospective study of plasma urate and risk of Parkinson disease in men and women

(2016) Xiang Gao et al.   NEUROLOGY

Can we use peripheral tissue biopsies to diagnose Parkinson's disease? A review of the literature

(2015) S. A. Schneider et al.   EUROPEAN JOURNAL OF NEUROLOGY

Constipation preceding Parkinson's disease: a systematic review and meta-analysis

(2015) Kerala L Adams-Carr et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Prediagnostic presentations of Parkinson's disease in primary care: a case-control study

(2015) Anette Schrag et al.   LANCET NEUROLOGY

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

MDS research criteria for prodromal Parkinson's disease

(2015) Daniela Berg et al.   MOVEMENT DISORDERS

Nigro-caudate dopaminergic deafferentation: a marker of REM sleep behavior disorder?

(2015) Dario Arnaldi et al.   NEUROBIOLOGY OF AGING

Depression and subsequent risk of Parkinson disease: A nationwide cohort study

(2015) H. Gustafsson et al.   NEUROLOGY

Parkinson risk in idiopathic REM sleep behavior disorder: Preparing for neuroprotective trials

(2015) R. B. Postuma et al.   NEUROLOGY

Neuroimaging of Parkinson's disease: Expanding views

(2015) Carol P. Weingarten et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Concept of Prodromal Parkinson’s Disease

(2015) Philipp Mahlknecht et al.   Journal of Parkinsons Disease

Cerebrospinal Fluid α-Synuclein Predicts Cognitive Decline in Parkinson Disease Progression in the DATATOP Cohort

(2014) Tessandra Stewart et al.   AMERICAN JOURNAL OF PATHOLOGY

Premotor and nonmotor features of Parkinsonʼs disease

(2014) Jennifer G. Goldman et al.   CURRENT OPINION IN NEUROLOGY

VPS35 Parkinson’s disease phenotype resembles the sporadic disease

(2014) Walter Struhal et al.   JOURNAL OF NEURAL TRANSMISSION

Imaging prodromal Parkinson disease: The Parkinson Associated Risk Syndrome Study

(2014) D. Jennings et al.   NEUROLOGY

Skin nerve  -synuclein deposits: A biomarker for idiopathic Parkinson disease

(2014) V. Donadio et al.   NEUROLOGY

LRRK2 parkinsonism in Tunisia and Norway: A comparative analysis of disease penetrance

(2014) F. Hentati et al.   NEUROLOGY

Depression and Parkinson’s Disease: Current Knowledge

(2013) Laura Marsh   Current Neurology and Neuroscience Reports

TheVPS35gene and Parkinson's disease

(2013) Hao Deng et al.   MOVEMENT DISORDERS

Prodromal autonomic symptoms and signs in Parkinson's disease and dementia with Lewy bodies

(2013) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Olfaction and imaging biomarkers in premotor LRRK2 G2019S-associated Parkinson disease

(2013) M. Sierra et al.   NEUROLOGY

Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series

(2013) Carlos H. Schenck et al.   SLEEP MEDICINE

How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder

(2012) R. B. Postuma et al.   BRAIN

The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

(2012) Koichi Wakabayashi et al.   MOLECULAR NEUROBIOLOGY

Identifying prodromal Parkinson's disease: Pre-Motor disorders in Parkinson's disease

(2012) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Calibration of unified Parkinson's disease rating scale scores toMovementDisorder Society-unified Parkinson's disease rating scale scores

(2012) Christopher G. Goetz et al.   MOVEMENT DISORDERS

A Prospective Study of Bowel Movement Frequency and Risk of Parkinson's Disease

(2011) X. Gao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Daytime Napping, Nighttime Sleeping, and Parkinson Disease

(2011) Jianjun Gao et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study

(2011) Alex Iranzo et al.   LANCET NEUROLOGY

Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study

(2010) Alex Iranzo et al.   LANCET NEUROLOGY

Anxious personality predicts an increased risk of Parkinson's disease

(2010) James H. Bower et al.   MOVEMENT DISORDERS

Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease

(2010) Jan O. Aasly et al.   MOVEMENT DISORDERS

Dopamine turnover increases in asymptomatic LRRK2 mutations carriers

(2010) Vesna Sossi et al.   MOVEMENT DISORDERS

Genealogical studies in LRRK2-associated Parkinson’s disease in central Norway

(2010) Krisztina K. Johansen et al.   PARKINSONISM & RELATED DISORDERS

Plasma Urate and Parkinson's Disease in the Atherosclerosis Risk in Communities (ARIC) Study

(2009) H. Chen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's disease

(2009) M. M Ponsen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of olfactory dysfunction with risk for future Parkinson's disease

(2007) G. Webster Ross et al.   ANNALS OF NEUROLOGY