Efficacy and Safety of Probiotics in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis

A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome

(2018) Shamsuddin M. Ishaque et al.   BMC GASTROENTEROLOGY

A double blind, placebo-controlled, randomized clinical trial that breast milk derived-Lactobacillus gasseri BNR17 mitigated diarrhea-dominant irritable bowel syndrome

(2018) Suk Pyo Shin et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The effect of Clostridium butyricum on symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial

(2018) Yi-Yuan Sun et al.   Scientific Reports

Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study

(2018) K. Preston et al.   Beneficial Microbes

Efficacy and Safety of Once-Daily Linaclotide Administered Orally for 26 Weeks in Patients With IBS-C: Results From a Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial

(2018) William D. Chey et al.   GASTROENTEROLOGY

Effect of Lactobacillus gasseri BNR17 on irritable bowel syndrome: a randomized, double-blind, placebo-controlled, dose-finding trial

(2017) Ji Yeon Kim et al.   FOOD SCIENCE AND BIOTECHNOLOGY

A double-blind, placebo-controlled study to assess the effect of a probiotic mixture on symptoms and inflammatory markers in women with diarrhea-predominant IBS

(2017) K. Hod et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effects of baseline abdominal pain and bloating on response to lubiprostone in patients with irritable bowel syndrome with constipation

(2016) L. Chang et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Modern Management of Irritable Bowel Syndrome: More Than Motility

(2016) Jan Tack et al.   DIGESTIVE DISEASES

Efficacy of Lactobacillus casei Shirota for patients with irritable bowel syndrome

(2016) Annemieke Y. Thijssen et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Irritable bowel syndrome symptom severity improves equally with probiotic and placebo

(2016) Anna Lyra et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A Randomized, Double-Blind, Placebo-Controlled Trial: The Efficacy of Multispecies Probiotic Supplementation in Alleviating Symptoms of Irritable Bowel Syndrome Associated with Constipation

(2016) Valerio Mezzasalma et al.   Biomed Research International

Ehealth: Low FODMAP dietvs Lactobacillus rhamnosusGG in irritable bowel syndrome

(2016) Natalia Pedersen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome

(2015) Guillaume Pineton de Chambrun et al.   DIGESTIVE AND LIVER DISEASE

Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial

(2015) Hyuk Yoon et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study

(2015) Muhammed Majeed et al.   Nutrition Journal

Randomized double blind placebo-controlled trial of Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: improvement in abdominal pain and bloating in those with predominant constipation

(2015) Robin Spiller et al.   United European Gastroenterology Journal

Randomised clinical trial: a liquid multi-strain probiotic vs. placebo in the irritable bowel syndrome - a 12 week double-blind study

(2014) G. Sisson et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets

(2014) H. L. DuPont   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Selective Serotonin Reuptake Inhibitors for the Treatment of Irritable Bowel Syndrome

(2014) Andrew W. Bundeff et al.   ANNALS OF PHARMACOTHERAPY

Medication Management of Irritable Bowel Syndrome

(2014) Katy E. Trinkley et al.   DIGESTION

Cytokine and clinical response to Saccharomyces boulardii therapy in diarrhea-dominant irritable bowel syndrome

(2014) Zaigham Abbas et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

The safety of novel drugs used to treat irritable bowel syndrome

(2014) Shilan Mozaffari et al.   Expert Opinion On Drug Safety

Randomized clinical trial on the effect of a multispecies probiotic on visceroperception in hypersensitive IBS patients

(2014) S. Ludidi et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Randomized clinical trial: Effect of Lactobacillus plantarum 299 v on symptoms of irritable bowel syndrome

(2014) Cheryl Stevenson et al.   NUTRITION

I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life

(2014) Vicente Lorenzo-Zúñiga   WORLD JOURNAL OF GASTROENTEROLOGY

A randomised controlled trial of a probiotic ‘functional food’ in the management of irritable bowel syndrome

(2013) Lesley M Roberts et al.   BMC GASTROENTEROLOGY

Instability of the faecal microbiota in diarrhoea-predominant irritable bowel syndrome

(2013) Ana Durbán et al.   FEMS MICROBIOLOGY ECOLOGY

Faecal microbiota composition and host–microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome

(2013) Jonna Jalanka-Tuovinen et al.   GUT

Effect of multispecies probiotics on irritable bowel syndrome: A randomized, double-blind, placebo-controlled trial

(2013) Jun Sik Yoon et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Long-term treatment with probiotics in primary care patients with irritable bowel syndrome – a randomised, double-blind, placebo controlled trial

(2013) Luise Mølenberg Begtrup et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Irritable bowel syndrome, inflammatory bowel disease and the microbiome

(2013) Giles Major et al.   Current Opinion in Endocrinology Diabetes and Obesity

The impact of Irritable Bowel Syndrome on health-related quality of life: a Singapore perspective

(2012) Yu Tien Wang et al.   BMC GASTROENTEROLOGY

Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis

(2012) Rebecca M. Lovell et al.   Clinical Gastroenterology and Hepatology

Intestinal microbiota in functional bowel disorders: a Rome foundation report

(2012) Magnus Simrén et al.   GUT

Depigmenting Effect of Kojic Acid Esters in Hyperpigmented B16F1 Melanoma Cells

(2012) Ahmad Firdaus B. Lajis et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

World Gastroenterology Organisation Global Guidelines

(2012) Francisco Guarner et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Efficacy and safety profile of LCR35 complete freeze-dried culture in irritable bowel syndrome: A randomized, double-blind study

(2012) Michel Dapoigny   WORLD JOURNAL OF GASTROENTEROLOGY

Clinical trial:Lactobacillus plantarum299v (DSM 9843) improves symptoms of irritable bowel syndrome

(2012) Philippe Ducrotté   WORLD JOURNAL OF GASTROENTEROLOGY

Probiotics, Symptoms, and Gut Microbiota: What Are the Relations? A Randomized Controlled Trial in Subjects with Irritable Bowel Syndrome

(2012) Per G. Farup et al.   Gastroenterology Research and Practice

Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life -- a double-blind, placebo-controlled study

(2011) S. Guglielmetti et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota

(2011) Ian B Jeffery et al.   GUT

A double-blind placebo-controlled trial to study therapeutic effects of probiotic Escherichia coli Nissle 1917 in subgroups of patients with irritable bowel syndrome

(2011) Wolfgang Kruis et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

A Randomized, Double-blind, Placebo-controlled Multicenter Trial of Saccharomyces boulardii in Irritable Bowel Syndrome

(2011) Chang Hwan Choi et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

The Effect of a Multispecies Probiotic Mixture on the Symptoms and Fecal Microbiota in Diarrhea-dominant Irritable Bowel Syndrome

(2011) Bong Ki Cha et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Effects of probiotic fermented milk on symptoms and intestinal flora in patients with irritable bowel syndrome: A randomized, placebo-controlled trial

(2011) Bo Søndergaard et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Effect of Probiotics on Symptoms in Korean Adults with Irritable Bowel Syndrome

(2010) Kyoung Sup Hong et al.   Gut and Liver

Gut Microbiota is Not Modified by Randomized, Double-Blind, Placebo-Controlled Trial of VSL#3 in Diarrhea-Predominant Irritable Bowel Syndrome

(2010) Sonia Michail et al.   Probiotics and Antimicrobial Proteins

Clinical trial: the effect of a fermented milk containing three probiotic bacteria in patients with irritable bowel syndrome (IBS) - a randomized, double-blind, controlled study

(2009) M. SIMRÉN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Irritable bowel syndrome: Role of food in pathogenesis and management

(2009) Ashraf MORCOS et al.   Journal of Digestive Diseases

Efficacy of tricyclic antidepressants in irritable bowel syndrome: A meta-analysis

(2009) Roja Rahimi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Randomized Controlled Treatment Trial of Irritable Bowel Syndrome with a Probiotic E.-coli Preparation (DSM17252) Compared to Placebo

(2009) P Enck et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome

(2008) J. ZENG et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study

(2008) E. A. WILLIAMS et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Clinical trial: the effects of a fermented milk product containingBifidobacterium lactisDN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation

(2008) A. AGRAWAL et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Gastrointestinal Microbiota in Irritable Bowel Syndrome: Their Role in Its Pathogenesis and Treatment

(2008) Gareth C. Parkes et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Effects of 5-Hydroxytryptamine (Serotonin) Type 3 Antagonists on Symptom Relief and Constipation in Nonconstipated Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2008) Viola Andresen et al.   Clinical Gastroenterology and Hepatology

Therapeutic Effect of Lactobacillus acidophilus-SDC 2012, 2013 in Patients with Irritable Bowel Syndrome

(2008) Dong Hyun Sinn et al.   DIGESTIVE DISEASES AND SCIENCES

A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome

(2008) S. Drouault-Holowacz et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

A mixture ofEscherichia coli(DSM 17252) andEnterococcus faecalis(DSM 16440) for treatment of the irritable bowel syndrome - A randomized controlled trial with primary care physicians

(2008) p. enck et al.   NEUROGASTROENTEROLOGY AND MOTILITY