Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway
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Title
Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway
Authors
Keywords
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Journal
Frontiers in Neuroscience
Volume 14, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-04-02
DOI
10.3389/fnins.2020.00223
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Note: Only part of the references are listed.- Connexin43 contributes to inflammasome activation and LPS-initiated acute renal injury via modulation of intracellular oxidative status
- (2019) Yanru Huang et al. ANTIOXIDANTS & REDOX SIGNALING
- Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts
- (2018) Sangmi Ock et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Role of Inflammatory Response in Stroke Associated Programmed Cell Death
- (2018) K. Duris et al. Current Neuropharmacology
- An update on vinpocetine: New discoveries and clinical implications
- (2018) Yi-shuai Zhang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone
- (2018) Xiang Yin et al. Journal of Neuroinflammation
- Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
- (2017) Li-Rong Wu et al. Oncotarget
- Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients
- (2017) Fang Zhang et al. Translational Stroke Research
- Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions
- (2017) Yancy Ferrer-Acosta et al. Jove-Journal of Visualized Experiments
- Reactive astrocytes and therapeutic potential in focal ischemic stroke
- (2016) Gourav Roy Choudhury et al. NEUROBIOLOGY OF DISEASE
- Astrocytes: Integrative Regulators of Neuroinflammation in Stroke and Other Neurological Diseases
- (2016) Egle Cekanaviciute et al. Neurotherapeutics
- Inflammation and Stroke: An Overview
- (2016) Josef Anrather et al. Neurotherapeutics
- Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke
- (2016) Zhongwu Liu et al. PROGRESS IN NEUROBIOLOGY
- Inflammation after Ischemic Stroke: The Role of Leukocytes and Glial Cells
- (2016) Jong Youl Kim et al. Experimental Neurobiology
- Vinpocetine modulates metabolic activity and function during retinal ischemia
- (2015) Lisa Nivison-Smith et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Inflammatory Responses in Brain Ischemia
- (2015) Masahito Kawabori et al. CURRENT MEDICINAL CHEMISTRY
- Atorvastatin protects myocardium against ischemia–reperfusion arrhythmia by increasing Connexin 43 expression: A rat model
- (2015) Bo Bian et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Energy Metabolism of the Brain, Including the Cooperation between Astrocytes and Neurons, Especially in the Context of Glycogen Metabolism
- (2015) Anna Falkowska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Relationship between Dysphagia, National Institutes of Health Stroke Scale Score, and Predictors of Pneumonia after Ischemic Stroke
- (2015) Priscila W. Ribeiro et al. Journal of Stroke & Cerebrovascular Diseases
- Drip and Ship Thrombolytic Therapy for Acute Ischemic Stroke
- (2015) Kevin N. Sheth et al. STROKE
- Relationship between Dysphagia, National Institutes of Health Stroke Scale Score, and Predictors of Pneumonia after Ischemic Stroke
- (2015) Priscila W. Ribeiro et al. Journal of Stroke & Cerebrovascular Diseases
- Specific Cx43 phosphorylation events regulate gap junction turnover in vivo
- (2014) Joell L. Solan et al. FEBS LETTERS
- Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation
- (2014) Nidhi Batra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-inflammatory effects of vinpocetine on the functional expression of nuclear factor-kappa B and tumor necrosis factor-alpha in a rat model of cerebral ischemia–reperfusion injury
- (2014) Hongxin Wang et al. NEUROSCIENCE LETTERS
- Vesicular Trafficking and Stress Response Coupled to PI3K Inhibition by LY294002 as Revealed by Proteomic and Cell Biological Analysis
- (2013) Tomáš Takáč et al. JOURNAL OF PROTEOME RESEARCH
- The effect of PI3 kinase inhibitor LY294002 on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells
- (2013) Da Hye Hong et al. LIFE SCIENCES
- Isolation and Culture of Mouse Cortical Astrocytes
- (2013) Sebastian Schildge et al. Jove-Journal of Visualized Experiments
- ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
- (2011) Juan A. Orellana et al. JOURNAL OF NEUROCHEMISTRY
- Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor
- (2011) S.-M. Maira et al. MOLECULAR CANCER THERAPEUTICS
- Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer
- (2011) Matthew T. Burger et al. ACS Medicinal Chemistry Letters
- Role of connexin43 in central nervous system injury
- (2010) Shenton S.L. Chew et al. EXPERIMENTAL NEUROLOGY
- Vinpocetine inhibits NF- B-dependent inflammation via an IKK-dependent but PDE-independent mechanism
- (2010) K.-I. Jeon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histology of the Central Nervous System
- (2010) Robert H. Garman TOXICOLOGIC PATHOLOGY
- The steady-state expression of connexin43 is maintained by the PI3K/Akt in osteoblasts
- (2009) Rajib Bhattacharjee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) Joell L. Solan et al. BIOCHEMICAL JOURNAL
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