Oxidative Stress-Induced Axon Fragmentation Is a Consequence of Reduced Axonal Transport in Hereditary Spastic Paraplegia SPAST Patient Neurons

Microtubule-Based Transport and the Distribution, Tethering, and Organization of Organelles

(2017) Kari Barlan et al.   Cold Spring Harbor Perspectives in Biology

Reactive oxygen species induce neurite degeneration before induction of cell death

(2016) Koji Fukui   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Mechanism of impaired microtubule-dependent peroxisome trafficking and oxidative stress in SPAST-mutated cells from patients with Hereditary Spastic Paraplegia

(2016) Gautam Wali et al.   Scientific Reports

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

(2014) S. Havlicek et al.   HUMAN MOLECULAR GENETICS

The Global Epidemiology of Hereditary Ataxia and Spastic Paraplegia: A Systematic Review of Prevalence Studies

(2014) Luis Ruano et al.   NEUROEPIDEMIOLOGY

Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia

(2014) Y. Fan et al.   Biology Open

Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells

(2013) Asif M. Maroof et al.   Cell Stem Cell

Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia

(2013) Kyle R. Denton et al.   STEM CELLS

A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations

(2012) G. Abrahamsen et al.   Disease Models & Mechanisms

SPASTmutations in Australian patients with hereditary spastic paraplegia

(2012) H. Vandebona et al.   INTERNAL MEDICINE JOURNAL

Oxidative stress inhibits axonal transport: implications for neurodegenerative diseases

(2012) Cheng Fang et al.   Molecular Neurodegeneration

Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system

(2010) Sheena Abraham et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of mouse oocyte microtubule and organelle dynamics by PADI6 and the cytoplasmic lattices

(2010) Rui Kan et al.   DEVELOPMENTAL BIOLOGY

Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

(2010) Astrid Bottelbergs et al.   GLIA

Specific pattern of early white-matter changes in pure hereditary spastic paraplegia

(2010) Thomas Duning et al.   MOVEMENT DISORDERS

Deficits in axonal transport precede ALS symptoms in vivo

(2010) L. G. Bilsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisomes Are Oxidative Organelles

(2009) Vasily D. Antonenkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

(2009) Paul R. Kasher et al.   JOURNAL OF NEUROCHEMISTRY

Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Peroxisome Dynamics in Cultured Mammalian Cells

(2009) Sofie J. Huybrechts et al.   TRAFFIC

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

(2008) Sara Salinas et al.   LANCET NEUROLOGY