Article
Neurosciences
Lucas Albrechet-Souza, Andrei S. Nastase, Matthew N. Hill, Nicholas W. Gilpin
Summary: Understanding sex-specific effects of predator odor stress on amygdalar endocannabinoids may provide insights into the vulnerability to chronic psychiatric disorders. This study revealed differences in endocannabinoid levels in the amygdala of male and female rats exposed to stress, with implications for behavior regulation in females.
NEUROBIOLOGY OF STRESS
(2021)
Article
Pharmacology & Pharmacy
Natalia Malikowska-Racia, Kinga Salat, Joanna Gdula-Argasinska, Piotr Popik
Summary: The study found that women are twice as likely to develop PTSD as men, and the role of sex hormones in this disorder remains unclear. Chronic treatment with GABA-ergic and dopamine-mimetic medications showed potential in improving PTSD-like symptoms, with a sex-dependent efficacy observed in female and male mice.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Psychology, Biological
Carlos R. Maestas-Olguin, Madeline M. Parish, Nathan S. Pentkowski
Summary: Studies have shown that commercially available coyote urine is effective in inducing a complete profile of anti-predator defensive behaviors, while 2-phenylethylamine (PEA) does not achieve the same effect. Therefore, coyote urine may be an effective defense-inducing unconditioned predator odor stimulus.
PHYSIOLOGY & BEHAVIOR
(2021)
Article
Behavioral Sciences
Laura C. Ornelas, Ryan E. Tyler, Preethi Irukulapati, Sudheesha Paladugu, Joyce Besheer
Summary: The study revealed that female rats with high digging/low immobility behavior during exposure to TMT were associated with increased alcohol self-administration, while this association was not observed in rats with low digging/high immobility behavior. These findings suggest that individual differences in stress-reactivity can influence alcohol consumption behavior, particularly in females.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Behavioral Sciences
Tomasz Bielawski, Jaroslaw Drapala, Pawel Krowicki, Bartlomiej Stanczykiewicz, Dorota Frydecka
Summary: Trauma and chronic stress from a fast-paced lifestyle can result in cognitive decline and behavioral problems. This study used an animal model and found that chronic exposure to predator odor led to decreased reinforcement learning and altered behavior in rats. The findings highlight the impact of trauma on cognitive abilities.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Psychology, Biological
Nathan S. Pentkowski, Carlos Maestas-Olguin, Gabriela Martinez
Summary: Predator odors play a critical role in eliciting defensive behavior in prey species. This study investigates the effects of commercially available predator odors on adolescent male and female rats. The results show that the predator odors can induce defensive behavior, but the response is moderate compared to previous studies.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Neurosciences
Viren H. Makhijani, Janay P. Franklin, Kalynn Van Voorhies, Brayden Fortino, Joyce Besheer
Summary: The studies showed that exposure of male rats to TMT can lead to escalations in sweetened alcohol self-administration and reduction in BLA response to alcohol, and the frequency of exposure may influence the outcomes.
PSYCHOPHARMACOLOGY
(2021)
Article
Clinical Neurology
Lindsey K. Freeman, Mary Beth Miller, Angelynn Simenson, Emilie Sparrow, Amy N. Costa, Madison Musich, Christina S. McCrae, Ashley F. Curtis
Summary: There is a gender difference in the association between alcohol use and sleep patterns in middle-aged and older adults. Alcohol use is related to better subjective sleep quality in women but not in men.
Article
Behavioral Sciences
Mehrdad Alavi, Andrey E. Ryabinin, Melinda L. Helms, Michelle A. Nipper, Leslie L. Devaud, Deborah A. Finn
Summary: Stress can increase ethanol drinking, and there is an association between post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD). Predator stress (PS), used as an animal model of PTSD, increases anxiety-related behavior and ethanol intake in mice, with variations in response similar to comorbid PTSD and AUD. These effects are influenced by sex and involve changes in proteins related to stress and anxiety responses.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Neurosciences
Rishi Sharma, Pradeep Sahota, Mahesh M. Thakkar
Summary: PTSD is a debilitating neuropsychiatric illness that affects memory function. Sleep is crucial for memory consolidation, and sleep deprivation may attenuate memory consolidation and lead to sleep disturbances.
Article
Psychology, Clinical
Kenny Wolfs, Arjan E. R. Bos, Fraukje E. F. Mevissen, Jacques J. D. M. van Lankveld
Summary: This study applied a dual-process model to investigate condomless sexual behavior, and found that alcohol intoxication and sexual arousal have significant effects on working memory capacity, but their combined effect does not significantly impact intentions to use a condom. Implicit attitudes do not directly affect intentions to use a condom, but may have some influence when participants are in a state of alcohol intoxication.
ARCHIVES OF SEXUAL BEHAVIOR
(2023)
Article
Endocrinology & Metabolism
Breanna N. Harris, Breanna R. Roberts, Giuliana M. DiMarco, Kaylee Alers Maldonado, Zenobia Okwunwanne, Alena V. Savonenko, Paul L. Soto
Summary: Alzheimer's disease is a progressive disorder that affects cognitive, behavioral, and emotional functions. The cause of the disease is not fully understood, but stress and anxiety-related hormones may be involved. The study found that glucocorticoid levels increase with age and stressor exposure, but the magnitude of the increase does not change with age. Transgenic mice had higher post-stressor corticosterone levels, and female mice had higher corticosterone levels than males. Transgenic females showed more anxiety-like behavior. There were no significant differences between genotypes in recognition memory.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2023)
Article
Substance Abuse
Nathan T. Kearns, Heidemarie Blumenthal, Ateka A. Contractor, Casey R. Guillot, Hanan Rafiuddin
Summary: This study investigated the impact of bodily arousal on alcohol craving among college students exposed to trauma, finding that trauma type may play a role in this relationship. The results suggest that bodily arousal may only increase desire to drink within a specific subset of trauma-exposed college students.
Article
Neurosciences
Dean Kirson, Michael Q. Steinman, Sarah A. Wolfe, Samantha R. Spierling Bagsic, Michal Bajo, Suhas Sureshchandra, Christopher S. Oleata, Ilhem Messaoudi, Eric P. Zorrilla, Marisa Roberto
Summary: Alcohol use disorder (AUD) and affective disorders often coexist and share similar mechanisms. Male rats are more influenced by stress in familiar environments, while females are more affected in novel environments. By modifying alcohol history and trauma context, the study revealed important factors in vulnerability to comorbid AUD/PTSD-like symptoms.
JOURNAL OF NEUROSCIENCE RESEARCH
(2021)
Article
Immunology
Cana B. Quave, Steven J. Nieto, Colin N. Haile, Therese A. Kosten
Summary: The study found that stress can activate Toll-like receptors (TLRs) in the immune system, leading to increased susceptibility to depression in females. In rat experiments, female KO rats showed reduced center time after exposure to predator odor, while genotype did not affect this response in male rats.
BRAIN, BEHAVIOR, & IMMUNITY - HEALTH
(2021)
Article
Substance Abuse
Lucas Albrechet-Souza, Lara S. Hwa, Xiao Han, Eric Y. Zhang, Joseph F. DeBold, Klaus A. Miczek
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2015)
Article
Pharmacology & Pharmacy
Lucas Albrechet-Souza, Thiago W. Viola, Rodrigo Grassi-Oliveira, Klaus A. Miczek, Rosa M. M. de Almeida
FRONTIERS IN PHARMACOLOGY
(2017)
Article
Behavioral Sciences
Mailton Vasconcelos, Dirson J. Stein, Lucas Albrechet-Souza, Klaus A. Miczek, Rosa Maria M. de Almeida
BEHAVIOURAL BRAIN RESEARCH
(2019)
Article
Neurosciences
Emily L. Newman, Lucas Albrechet-Souza, Peter M. Andrew, John G. Auld, Kelly C. Burk, Lara S. Hwa, Eric Y. Zhang, Joseph F. DeBold, Klaus A. Miczek
PSYCHOPHARMACOLOGY
(2018)
Article
Behavioral Sciences
Karina G. Borelli, Lucas Albrechet-Souza, Alessandra G. Fedoce, Denise S. Fabri, Leonardo B. Resstel, Marcus L. Brandao
HORMONES AND BEHAVIOR
(2013)
Article
Neurosciences
Christopher O. Boyson, Elizabeth N. Holly, Akiko Shimamoto, Lucas Albrechet-Souza, Lindsay A. Weiner, Joseph F. DeBold, Klaus A. Miczek
JOURNAL OF NEUROSCIENCE
(2014)
Article
Neurosciences
Xiao Han, Lucas Albrechet-Souza, Michelle R. Doyle, Akiko Shimamoto, Joseph F. DeBold, Klaus A. Miczek
PSYCHOPHARMACOLOGY
(2015)
Article
Endocrinology & Metabolism
Thiago Wendt Viola, Luis Eduardo Wearick-Silva, Kerstin C. Creutzberg, Erika Kestering-Ferreira, Rodrigo Orso, Anderson Centeno-Silva, Lucas Albrechet-Souza, Paul R. Marshall, Xiang Li, Timothy W. Bredy, Marco A. Riva, Rodrigo Grassi-Oliveira
PSYCHONEUROENDOCRINOLOGY
(2019)
Review
Behavioral Sciences
Lucas Albrechet-Souza, Nicholas W. Gilpin
BEHAVIOURAL PHARMACOLOGY
(2019)
Article
Education, Scientific Disciplines
Flavia M. Souza-Smith, Lucas Albrechet-Souza, Elizabeth M. Avegno, Chloe D. Ball, Tekeda F. Ferguson, Lisa M. Harrison-Bernard, Patricia E. Molina
Summary: The current heightened social awareness and anxiety over escalating violence against Black Americans in the United States has led to a demand for a safe space for reflection, education, and civil discourse within academic settings. The authors propose a shared learning approach to discuss perspectives against racism.
ADVANCES IN PHYSIOLOGY EDUCATION
(2021)
Article
Neurosciences
Lucas Albrechet-Souza, Andrei S. Nastase, Matthew N. Hill, Nicholas W. Gilpin
Summary: Understanding sex-specific effects of predator odor stress on amygdalar endocannabinoids may provide insights into the vulnerability to chronic psychiatric disorders. This study revealed differences in endocannabinoid levels in the amygdala of male and female rats exposed to stress, with implications for behavior regulation in females.
NEUROBIOLOGY OF STRESS
(2021)
Article
Behavioral Sciences
D. Parker Kelley, Lucas Albrechet-Souza, Shealan Cruise, Rajani Maiya, Aspasia Destouni, Siva S. V. P. Sakamuri, Alexander Duplooy, Meghan Hibicke, Charles Nichols, Prasad V. G. Katakam, Nicholas W. Gilpin, Joseph Francis
Summary: Stress is associated with contextual memory deficits, which may lead to avoidance of trauma-associated contexts in posttraumatic stress disorder. These deficits may result from impaired pattern separation in the brain, which affects the ability to distinguish similar experiences. The production of reactive oxygen species in the hippocampus has been found to be related to pattern separation and may play a role in the effects of stress on memory.
GENES BRAIN AND BEHAVIOR
(2023)
Review
Behavioral Sciences
Dirson J. Stein, Mailton F. Vasconcelos, Lucas Albrechet-Souza, Keila M. M. Cereser, Rosa M. M. de Almeida
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2017)
Article
Psychiatry
Paula Madeira Fortes, Lucas Albrechet-Souza, Mailton Vasconcelos, Bruna Maria Ascoli, Ana Paula Menegolla, Rosa Maria M. de Almeida
TRENDS IN PSYCHIATRY AND PSYCHOTHERAPY
(2017)