Review
Surgery
Paola Solis-Pazmino, Kimberly Oka, Kristina La, Orly Termeie, Luis A. Figueroa, Eduardo Pilatuna, Daniel Solis-Pazmino, Mary Pat Harnegie, Jason Cohen, Moshe Barnajian, Yosef Nasseri
Summary: This meta-analysis and systematic review examined the rates and types of appendiceal neoplasm between complicated and uncomplicated appendicitis. The overall neoplasm rate did not differ significantly between the two groups, but the rate of neuroendocrine tumors (NET) was higher in uncomplicated appendicitis, while the rate of adenocarcinoma was higher in complicated appendicitis.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Surgery
Danielle Hayes, Shelby Reiter, Edard Hagen, Gary Lucas, Isabelle Chu, Tobias Muniz, Ryan Martinez
Summary: The risk of occult appendiceal neoplasm is low in patients under the age of 30; however, the rate of appendiceal neoplasm in patients 30 years and older is 11%, increasing with age to 16% for patients 50 years and older. Considering these findings, it is recommended to consider interval appendectomy in all patients 30 years and older with complicated appendicitis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Takuya Sugimoto, Yasutomo Nagasue, Eiji Tanaka, Hiroshi Yokomizo
Summary: This study compared the occurrence rates of appendiceal tumors between uncomplicated and complicated appendicitis. It found that among patients aged >= 60 years, the incidence of appendiceal tumors was significantly higher in complicated appendicitis than in uncomplicated appendicitis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Masahiro Shiihara, Yasuhiro Sudo, Norimasa Matsushita, Takeshi Kubota, Yasuhiro Hibi, Harushi Osugi, Tatsuo Inoue
Summary: This study retrospectively analyzed 305 patients with acute appendicitis, dividing them into an emergency surgery group and a conservative treatment group. Through multiple logistic regression analysis, C-reactive protein, ascites, appendiceal wall defect, and periappendiceal fluid collection were found to be independent risk factors for complicated appendicitis. The predictive nomogram based on these factors had an accuracy of 0.938 and can assist in distinguishing complicated appendicitis from uncomplicated appendicitis and predicting the success of conservative treatment.
Article
Multidisciplinary Sciences
Sanja Vanhatalo, Eveliina Munukka, Teemu Kallonen, Suvi Sippola, Juha Gronroos, Jussi Haijanen, Antti J. Hakanen, Paulina Salminen
Summary: This study compared the appendiceal microbiota in uncomplicated and complicated acute appendicitis and found that they have different microbial compositions. This study supports the idea of a disconnection between uncomplicated and complicated acute appendicitis.
Article
Medicine, General & Internal
Matthew Ashbrook, Vincent Cheng, Kulmeet Sandhu, Koji Matsuo, Morgan Schellenberg, Kenji Inaba, Kazuhide Matsushima
Summary: This study found that immediate operation for complicated appendicitis in pregnant women was associated with lower odds of maternal infectious complications without higher odds of perinatal or other maternal complications compared with successful nonoperative management. Failed nonoperative management was associated with worse clinical outcomes.
Article
Surgery
Wenjuan Ding, Zhiqiang Du, Xiangrong Zhou
Summary: The study found that ERAT is a safe and effective endoscopic treatment method for acute appendicitis and abscesses of the appendix. ERAT was associated with shorter operation time, reduced length of hospital stay, less time spent bedridden following surgery, fewer surgery-related complications, and lower in-patient expenses compared to LA and OA procedures.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Jun Fujishiro, Eiichiro Watanabe, Norimichi Hirahara, Keita Terui, Hirofumi Tomita, Tetsuya Ishimaru, Hiroaki Miyata
Summary: This study compared postoperative outcomes of laparoscopic and open appendectomies for acute appendicitis in children under widespread use of laparoscopic surgery. Results showed that there were no significant differences in postoperative complications and length of hospital stay between pediatric patients who underwent laparoscopic or open appendectomy, regardless of complicated or uncomplicated appendicitis cases.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Multidisciplinary Sciences
Yitian Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo
Summary: This study demonstrates a new entity of non-perforated appendicitis, acute hemorrhagic appendicitis, through studying a cluster of acute appendicitis among Tibetan students at a high school in central China. The clinical manifestations and pathological findings of this new type of appendicitis are unique, suggesting that it could be treated with antibiotics alone or self-limited.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Mounir Bouali, Yassine El Berni, Aziz Moufakkir, Abdelilah El Bakouri, Khalid El Hattabi, Fatimazahra Bensardi, Abdelaziz Fadil
Summary: This study evaluated the efficacy of the Alvarado scoring system in the preoperative diagnosis of acute appendicitis and found that it has high sensitivity and positive predictive value. Clinical experience remains crucial in diagnosing acute appendicitis.
ANNALS OF MEDICINE AND SURGERY
(2022)
Article
Pediatrics
Huan Li, Jianfeng Luo, Haibin Wang, Qin Guo, Peng Huang, Haiyan Lei, Wenhai Li, Jun Yang
Summary: This study aims to explore the success rate of non-surgical treatment of appendiceal abscess in children under 3 years old and assess the potential influence of an appendicolith on the treatment outcomes. The results show that non-surgical treatment of appendiceal abscess has a high success rate in children under 3 years old.
FRONTIERS IN PEDIATRICS
(2023)
Article
Surgery
Bobby Zamaray, M. F. J. de Boer, Z. Popal, A. Rijbroek, F. W. Bloemers, S. J. Oosterling
Summary: This study compared the incidence of intra-abdominal abscesses after laparoscopic versus open appendectomy for complicated appendicitis.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
F. Haak, O. Kollmar, A. Ioannidis, J. E. Slotta, M. B. Ghadimi, T. Glass, M. von Strauss Und Torney
Summary: This study retrospectively analyzed two cohorts from Switzerland and Germany, investigating the ability of clinical scoring systems and imaging to differentiate between complicated and uncomplicated appendicitis. Results showed limited capability of the current scoring systems to distinguish between complicated and uncomplicated appendicitis.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Surgery
Tamer A. A. M. Habeeb, Abdulzahra Hussain, Francisco Schlottmann, Mohammad Kermansaravi, Alberto Aiolfi, Ivan Matic, Osama Abdelazez, Said Mohamed Negm, Muhammad Ali Baghdadi, Mahmoud Abdou Yassin, Ahmed M. Sallam, Hatem Mohammad, Fady Mehaney Habib, Mohamed Abdelhamid, Mohamed Farouk Amin
Summary: This study aimed to evaluate recurrent appendicitis after successful drainage of appendicular abscess during COVID-19. Results showed that 30.4% of patients experienced recurrent appendicitis after three months, with 56.3% of the recurrences occurring after three months. Age, diabetes, hypertension, COVID-19 infection, and abscess size >3 cm were significant risk factors for recurrent appendicitis. Interval appendectomy is recommended in older age, people with diabetes, COVID-19 infected individuals, and abscesses larger than 3 cm in order to prevent recurrent appendicitis.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Multidisciplinary Sciences
Muhammad Zeb, Sabir Khan Khattak, Maryam Samad, Syed Shayan Shah, Syed Qasim Ali Shah, Abdul Haseeb
Summary: This study compared the efficacy of Alvarado, AIR, and RIPASA scores in diagnosing acute appendicitis. The results showed that RIPASA score outperformed AIR and Alvarado scores in terms of sensitivity, accuracy, and area under the curve. AIR score performed better in terms of specificity, negative predictive value, and positive likelihood ratio. In conclusion, RIPASA score is a better scoring system for diagnosing acute appendicitis compared to Alvarado and AIR scores.
Article
Critical Care Medicine
Raul Coimbra, Timothy Allison-Aipa, Bishoy Zachary, Matthew Firek, Sara Edwards
Summary: This study aimed to identify risk factors associated with 30-day unplanned readmissions after emergency general surgery (EGS). Using a retrospective cohort study, the analysis revealed associations between patient characteristics such as age, anesthesia score, sepsis, body mass index, procedure risk, length of stay, and discharge disposition. Thirty-day readmissions were found to have higher incidence of surgical site infections, wound disruption, postoperative sepsis, and thromboembolic events.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2023)
Article
Emergency Medicine
Lorenzo Cobianchi, Daniele Piccolo, Francesca Dal Mas, Vanni Agnoletti, Luca Ansaloni, Jeremy Balch, Walter Biff, Giovanni Butturini, Fausto Catena, Federico Coccolini, Stefano Denicolai, Belinda De Simone, Isabella Frigerio, Paola Fugazzola, Gianluigi Marseglia, Giuseppe Roberto Marseglia, Jacopo Martellucci, Mirko Modenese, Pietro Previtali, Federico Ruta, Alessandro Venturi, Haytham M. Kaafarani, Tyler J. Loftus
Summary: This study investigates trauma and emergency surgeons' knowledge and perception of using AI-based tools in clinical decision-making processes. The results show that there are technology enthusiasts and skeptics among surgeons, with a preference towards more classical decision-making aids. Lack of knowledge about AI and mistrust are also observed.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Review
Emergency Medicine
Nicola De'Angelis, Francesco Marchegiani, Carlo Alberto Schena, Jim Khan, Vanni Agnoletti, Luca Ansaloni, Ana Gabriela Barria Rodriguez, Paolo Pietro Bianchi, Walter Biffl, Francesca Bravi, Graziano Ceccarelli, Marco Ceresoli, Osvaldo Chiara, Mircea Chirica, Lorenzo Cobianchi, Federico Coccolini, Raul Coimbra, Christian Cotsoglou, Mathieu D'Hondt, Dimitris Damaskos, Belinda De Simone, Salomone Di Saverio, Michele Diana, Eloy Espin-Basany, Stefan Fichtner-Feigl, Paola Fugazzola, Paschalis Gavriilidis, Caroline Gronnier, Jeffry Kashuk, Andrew W. Kirkpatrick, Michele Ammendola, Ewout A. Kouwenhoven, Alexis Laurent, Ari Leppaniemi, Mickael Lesurtel, Riccardo Memeo, Marco Milone, Ernest Moore, Nikolaos Pararas, Andrew Peitzmann, Patrick Pessaux, Edoardo Picetti, Manos Pikoulis, Michele Pisano, Frederic Ris, Tyler Robison, Massimo Sartelli, Vishal G. Shelat, Giuseppe Spinoglio, Michael Sugrue, Edward Tan, Ellen Van Eetvelde, Yoram Kluger, Dieter Weber, Fausto Catena
Summary: This paper summarizes the learning curve in emergency minimally invasive surgery (MIS) and provides expert opinion statements for standardized curricula and training programs. Limited evidence exists on the learning process, suggesting a need for further research. The training should include simulation, supervised clinical practice, and surgical fellowships to ensure quality standards.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Nutrition & Dietetics
Benjamin Hess, Martin Cahenzli, Alastair Forbes, Rosa Burgos, Federico Coccolini, Olivier Corcos, Mette Holst, Oivind Irtun, Stanislaw Klek, Loris Pironi, Henrik Hojgaard Rasmussen, Mireille J. Serlie, Ronan Thibault, Simon Gabe, Annika Reintam Blaser
Summary: This survey assesses current attitudes and practices in managing acute mesenteric ischemia (AMI) worldwide. Results show that diagnosis of AMI is often delayed but rarely missed. Abdominopelvic CT-scan with intravenous contrast was suggested as the most useful diagnostic test. Treatment approaches vary greatly, indicating the need for updated guidelines.
CLINICAL NUTRITION ESPEN
(2023)
Review
Emergency Medicine
Brian W. C. A. Tian, Gabriele Vigutto, Edward Tan, Harry van Goor, Cino Bendinelli, Fikri Abu-Zidan, Rao Ivatury, Boris Sakakushev, Isidoro Di Carlo, Gabriele Sganga, Ronald V. Maier, Raul Coimbra, Ari Leppaniemi, Andrey Litvin, Dimitrios Damaskos, Richard Ten Broek, Walter Biffl, Salomone Di Saverio, Belinda De Simone, Marco Ceresoli, Edoardo Picetti, Joseph Galante, Giovanni D. Tebala, Solomon Gurmu Beka, Luigi Bonavina, Yunfeng Cui, Jim Khan, Enrico Cicuttin, Francesco Amico, Inaba Kenji, Andreas Hecker, Luca Ansaloni, Massimo Sartelli, Ernest E. Moore, Yoram Kluger, Mario Testini, Dieter Weber, Vanni Agnoletti, Nicola De' Angelis, Federico Coccolini, Ibrahima Sall, Fausto Catena
Summary: Sigmoid volvulus is a common surgical emergency, especially in elderly patients, who can present with a wide range of clinical states. Urgent treatment, such as endoscopic decompression or colectomy, is generally required.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Emergency Medicine
Belinda De Simone, Yoram Kluger, Ernest Moore, Massimo Sartelli, Fikri Abu-Zidan, Federico Coccolini, Luca D. Ansaloni, Giovanni Tebala, Salomone Di Saverio, Isidoro Di Carlo, Boris Sakakushev, Luigi Bonavina, Michael E. Sugrue, Joseph Galante, Rao Ivatury, Edoardo Picetti, Mircea Chirica, Imtiaz Wani, Miklosh Bala, Ibrahima Sall, Andrew Kirkpatrick, Vishal Shelat, Emmanouil Pikoulis, Ari Leppaniemi, Edward Tan, Richard P. G. ten Broek, Solomon Gurmu Beka, Andrey Litvin, Elie Chouillard, Raul Coimbra, Yunfeng Cui, Nicola De' Angelis, Gabriele Sganga, Philip Stahel, Vanni Agnoletti, Alessia Rampini, Mario Testini, Francesca Bravi, Ronald V. Maier, Walter L. Biffl, Fausto Catena
Summary: This study aimed to improve the accuracy and effectiveness of the TACS classification for emergency general surgery (EGS) patients. By involving international experts through a standardized Delphi approach, the new TACS classification provides a comprehensive and reproducible triage system which can reduce waiting time and improve communication among medical professionals.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Surgery
Fabio Cesare Campanile, Mauro Podda, Francesca Pecchini, Marco Inama, Sarah Molfino, Marco Augusto Bonino, Monica Ortenzi, Gianfranco Silecchia, Ferdinando Agresta, Michela Cinquini
Summary: The Italian Society for Endoscopic Surgery (SICE) developed new guidelines on laparoscopic treatment of ventral hernias, which were accepted by the government agency and published on the SNLG website. The guidelines are based on extensive literature review and the rigorous GRADE method. However, they have limitations due to the rapidly evolving nature of the topic and their focus on minimally invasive techniques.
UPDATES IN SURGERY
(2023)
Article
Surgery
Mauro Podda, Gianluca Pellino, Salomone Di Saverio, Federico Coccolini, Daniela Pacella, Stefano Piero Bernardo Cloffi, Francesco Vlrdis, Andrea Balla, Benedetto Ielpo, Francesco Pata, Gaetano Poillucci, Monica Ortenzi, Dimitrios Damaskos, Belinda De Simone, Massimo Sartelli, Ari Leppaniemi, Kumar Jayant, Fausto Catena, Antonio Giuliani, Marcello Di Martino, Adolfo Pisanu
Summary: The identification of high-risk patients is crucial in the early stages of infected pancreatic necrosis (IPN) to determine appropriate management strategies. This study found that history of uncontrolled arterial hypertension, qSOFA score, renal failure, haemodynamic failure were independent predictors of mortality in IPN patients. Cholangitis, abdominal compartment syndrome, and gastrointestinal/intra-abdominal bleeding were associated with increased risk of mortality. Upfront open surgical necrosectomy was strongly associated with higher mortality risk, while endoscopic drainage of pancreatic necrosis and enteral nutrition were protective factors.
UPDATES IN SURGERY
(2023)
Article
Surgery
Joanna Shaw, Bishoy Zakhary, Raul Coimbra, Laura Moore, Thomas Scalea, Rishi Kundi, William Teeter, Anna Romagnoli, Ernest Moore, Angela Sauaia, Bradley Dennis, Megan Brenner
Summary: This study aimed to investigate the outcomes associated with the use of tranexamic acid (TXA) in high- and low-profile introducer sheaths for resuscitative endovascular balloon occlusion of the aorta (REBOA). The results showed that patients who received TXA had a higher risk of distal embolism. Therefore, strict protocols for immediate diagnosis and treatment of thrombotic complications should be followed when performing REBOA in patients receiving TXA.
Article
Surgery
Marcello Di Martino, Benedetto Ielpo, Francesco Pata, Gianluca Pellino, Salomone Di Saverio, Fausto Catena, Belinda De Simone, Federico Coccolini, Massimo Sartelli, Dimitrios Damaskos, Damian Mole, Valentina Murzi, Ari Leppaniemi, Adolfo Pisanu, Mauro Podda
Summary: The timing of cholecystectomy has a significant impact on the outcomes of patients with moderately severe and severe ABP. Early cholecystectomy is associated with higher postoperative mortality and morbidity. Elderly and frail patients with severe complications of ABP are unlikely to benefit from early cholecystectomy.
Review
Emergency Medicine
Federico Coccolini, Massimo Sartelli, Robert Sawyer, Kemal Rasa, Bruno Viaggi, Fikri Abu-Zidan, Kjetil Soreide, Timothy Hardcastle, Deepak Gupta, Cino Bendinelli, Marco Ceresoli, Vishal G. G. Shelat, Richard ten Broek, Gian Luca Baiocchi, Ernest E. E. Moore, Ibrahima Sall, Mauro Podda, Luigi Bonavina, Igor A. A. Kryvoruchko, Philip Stahel, Kenji Inaba, Philippe Montravers, Boris Sakakushev, Gabriele Sganga, Paolo Ballestracci, Manu L. N. G. Malbrain, Jean-Louis Vincent, Manos Pikoulis, Solomon Gurmu Beka, Krstina Doklestic, Massimo Chiarugi, Marco Falcone, Elena Bignami, Viktor Reva, Zaza Demetrashvili, Salomone Di Saverio, Matti Tolonen, Pradeep Navsaria, Miklosh Bala, Zsolt Balogh, Andrey Litvin, Andreas Hecker, Imtiaz Wani, Andreas Fette, Belinda De Simone, Rao Ivatury, Edoardo Picetti, Vladimir Khokha, Edward Tan, Chad Ball, Carlo Tascini, Yunfeng Cui, Raul Coimbra, Michael Kelly, Costanza Martino, Vanni Agnoletti, Marja A. A. Boermeester, Nicola De'Angelis, Mircea Chirica, Walt L. L. Biffl, Luca Ansaloni, Yoram Kluger, Fausto Catena, Andrew W. W. Kirkpatrick
Summary: Intra-abdominal infections are a common global healthcare challenge caused by disruption to the gastrointestinal tract. It requires intensive resource utilization and physical source control is often needed. Advances have been made in non-surgical interventional procedures and open abdomen techniques to aid source control. The concept and adequacy of source control in intra-abdominal infections need a multidisciplinary approach.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Surgery
Paola Fugazzola, Alessandro Moroni, Vanni Agnoletti, Fausto Catena, Lorenzo Cobianchi, Salvatore Corallo, Francesca Dal Mas, Simone Frassini, Marcello Maestri, Stefano Magnone, Anna Pagani, Paolo Pedrazzoli, Andrea Rigamonti, Giorgia Santandrea, Matteo Tomasoni, Carlo Vallicelli, Jacopo Vigano, Luca Ansaloni
Summary: This study analyzed the outcomes of patients with colorectal peritoneal carcinosis and a peritoneal cancer index (PCI) greater than or equal to 16 treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The results showed that patients with a PCI less than 16 had a 2-year overall survival rate of 81%, while patients with a PCI greater than or equal to 16 had a 2-year overall survival rate of only 37%. Therefore, current guidelines need to reassess the exclusion of these patients from CRS and HIPEC.
UPDATES IN SURGERY
(2023)
Article
Surgery
Sara Capoccia Giovannini, Mauro Podda, Sonia Ribas, Giulia Montori, Emanuele Botteri, Ferdinando Agresta, Alberto Sartori, Hana Charvatova, Alberto Aiolfi, Stavros A. Antoniou, Catherine Arvieux, Frederik Berrevoet, Marja A. Boermeester, Giampiero Campanelli, Srinivas Chintapatla, Mette Willaume Christoffersen, Ursula Dahlstrand, Hanna De la Croix, Ulrich A. Dietz, Antonio Ferreira, Rene H. Fortenly, Christine Gaarder, Miguel Angel Garcia Urena, Hakan Gok, Pilar Hernandez-Granados, Barbora Jisova, Orest Laver, Orest Lerchuk, Manuel Lopez-Cano, Manuel Mega, Krispin Mitura, Filip Muysoms, Andre Oliva, Monica Ortenzi, Ulf Petersson, Micaela Piccoli, Victor G. Radu, Yohann Renard, Peder Rogmark, Danny Rosin, Ana Senent-Boza, Maarten Simons, Dominic Slade, Neil Smart, Stella R. Smith, Cesare Stabilini, Alexis Theodorou, Jared Torkington, Jaanna Vironen, Guido Woeste, Andrew De Beaux, Barbora East
BRITISH JOURNAL OF SURGERY
(2023)
Article
Medicine, General & Internal
Valentina Murzi, Eleonora Locci, Alessandro Carta, Tiziana Pilia, Federica Frongia, Emanuela Gessa, Mauro Podda, Adolfo Pisanu
Summary: This study aimed to identify predictive factors for the failure of conservative treatment of Hinchey IIa and IIb diverticular abscesses. The study found that smoking was the only independent predictor associated with conservative treatment failure.
MEDICINA-LITHUANIA
(2023)