Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells

TTC3 contributes to TGF-β1-induced epithelial−mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation

(2019) June-Hyung Kim et al.   Cell Death & Disease

Roscovitine attenuates renal interstitial fibrosis in diabetic mice through the TGF-β1/p38 MAPK pathway

(2019) Shuo Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells

(2019) Seung Eun Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Chrysin Inhibits Advanced Glycation End Products-Induced Kidney Fibrosis in Renal Mesangial Cells and Diabetic Kidneys

(2018) Eun-Jung Lee et al.   Nutrients

Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro

(2018) Bo Liu et al.   Stem Cell Research & Therapy

Aloe-emodin ameliorates renal fibrosis via inhibiting PI3K/Akt/mTOR signaling pathway in vivo and in vitro

(2018) Fang Dou et al.   REJUVENATION RESEARCH

Notch signaling inhibits cardiac fibroblast to myofibroblast transformation by antagonizing TGF-β1/Smad3 signaling

(2018) Xue-liang Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Paracrine effect of mesenchymal stem cell as a novel therapeutic strategy for diabetic nephropathy

(2018) Hongde Li et al.   LIFE SCIENCES

Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

(2018) Nesrine Ebrahim et al.   Cells

Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3β/β-catenin pathway

(2017) Xiaoping Zhang et al.   EXPERIMENTAL CELL RESEARCH

Transplantation of human fetal pancreatic progenitor cells ameliorates renal injury in streptozotocin-induced diabetic nephropathy

(2017) Yongwei Jiang et al.   Journal of Translational Medicine

Pirfenidone suppresses MAPK signalling pathway to reverse epithelial-mesenchymal transition and renal fibrosis

(2017) Zhenzhen Li et al.   NEPHROLOGY

Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes

(2017) Xiaoming Wu et al.   Scientific Reports

The cellular and signalling alterations conducted by TGF-β contributing to renal fibrosis

(2016) Génesis Vega et al.   CYTOKINE

TGF-β: the connecting link between nephropathy and fibrosis

(2016) Brijesh Sutariya et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis

(2016) Bo Wang et al.   MOLECULAR THERAPY

Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

(2016) Kanna Nagaishi et al.   Scientific Reports

Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy

(2015) C. Hu et al.   CURRENT MEDICINAL CHEMISTRY

Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy

(2015) Tan Li et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway

(2015) Cheng Yang et al.   Journal of Translational Medicine

Proregenerative Microenvironment Triggered by Donor Mesenchymal Stem Cells Preserves Renal Function and Structure in Mice with Severe Diabetes Mellitus

(2015) Fernando Ezquer et al.   Biomed Research International

Tempol Attenuates Renal Fibrosis in Mice with Unilateral Ureteral Obstruction: The Role of PI3K-Akt-FoxO3a Signaling

(2014) Hye Eun Yoon et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Inhibition of the K+ Channel KCa3.1 Reduces TGF-β1-Induced Premature Senescence, Myofibroblast Phenotype Transition and Proliferation of Mesangial Cells

(2014) Rong-Guo Fu et al.   PLoS One

The role of bone marrow derived-mesenchymal stem cells in attenuation of kidney function in rats with diabetic nephropathy

(2014) Mohamed Abdel Aziz et al.   Diabetology & Metabolic Syndrome

Effect of miR-21 on Renal Fibrosis by Regulating MMP-9 and TIMP1 in kk-ay Diabetic Nephropathy Mice

(2013) Jinyang Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy

(2013) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Repeated Systemic Administration of Human Adipose-Derived Stem Cells Attenuates Overt Diabetic Nephropathy in Rats

(2013) Li Zhang et al.   STEM CELLS AND DEVELOPMENT

Human umbilical cord blood-derived mesenchymal stem cells prevent diabetic renal injury through paracrine action

(2012) Jong Hee Park et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Effects of High Glucose on AVP-Induced Hyperplasia, Hypertrophy, and Type IV Collagen Synthesis in Cultured Rat Mesangial Cells

(2012) Atsuo Tahara et al.   ENDOCRINE RESEARCH

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis

(2012) Timothy Bowen et al.   JOURNAL OF PATHOLOGY

Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy

(2012) Eric W Brunskill et al.   BMC Nephrology

Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor- : A Model for Diabetic Podocytopathy

(2011) M. Herman-Edelstein et al.   DIABETES

Potential New Therapeutic Agents for Diabetic Kidney Disease

(2010) Faruk Turgut et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Therapeutic Intervention in Diabetic Nephropathy

(2009) Claire E. Hills et al.   AMERICAN JOURNAL OF NEPHROLOGY

Endovenous Administration of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells Prevents Renal Failure in Diabetic Mice

(2009) Fernando Ezquer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION