Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic TNNT2 Gene Variants

Effect of Trimetazidine Dihydrochloride Therapy on Exercise Capacity in Patients With Nonobstructive Hypertrophic Cardiomyopathy

(2019) Caroline J. Coats et al.   JAMA Cardiology

Sex differences in hypertrophic cardiomyopathy

(2019) Beau van Driel et al.   CURRENT OPINION IN CARDIOLOGY

Mavacamten Treatment for Obstructive Hypertrophic Cardiomyopathy

(2019) Stephen B. Heitner et al.   ANNALS OF INTERNAL MEDICINE

Metabolic changes in hypertrophic cardiomyopathies: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology

(2018) Jolanda van der Velden et al.   CARDIOVASCULAR RESEARCH

Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy

(2018) Louise L.A.M. Nijenkamp et al.   Circulation-Heart Failure

Hypertrophic cardiomyopathy mutations increase myofilament Ca2+buffering, alter intracellular Ca2+handling, and stimulate Ca2+-dependent signaling

(2018) Paul Robinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

(2018) Nicoletta Piroddi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region

(2017) Binnu Gangadharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models

(2017) Cecilia Ferrantini et al.   Journal of the American Heart Association

Value of Genetic Testing for the Prediction of Long-Term Outcome in Patients With Hypertrophic Cardiomyopathy

(2016) Hannah G. van Velzen et al.   AMERICAN JOURNAL OF CARDIOLOGY

Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy

(2015) Liselotte B. Christiansen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Genetic advances in sarcomeric cardiomyopathies: state of the art

(2015) C. Y. Ho et al.   CARDIOVASCULAR RESEARCH

Targets for therapy in sarcomeric cardiomyopathies

(2015) J. C. Tardiff et al.   CARDIOVASCULAR RESEARCH

Left ventricular outflow tract gradient is associated with reduced capillary density in hypertrophic cardiomyopathy irrespective of genotype

(2015) Ahmet Güçlü et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

New Perspectives on the Prevalence of Hypertrophic Cardiomyopathy

(2015) Christopher Semsarian et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diltiazem Treatment for Pre-Clinical Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers

(2015) Carolyn Y. Ho et al.   JACC-Heart Failure

Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: A novel pathogenic mechanism for hypertrophic cardiomyopathy

(2014) Rachel K. Moore et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations

(2014) E. Rosalie Witjas-Paalberends et al.   CARDIOVASCULAR RESEARCH

2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy

(2014)   EUROPEAN HEART JOURNAL

Clinical Phenotype and Outcome of Hypertrophic Cardiomyopathy Associated With Thin-Filament Gene Mutations

(2014) Raffaele Coppini et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

(2013) Vasco Sequeira et al.   CIRCULATION RESEARCH

Reproducibility of myocardial strain and left ventricular twist measured using complementary spatial modulation of magnetization

(2013) Peter P. Swoboda et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Thin Filament Mutations

(2011) Jil C. Tardiff   CIRCULATION RESEARCH

Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction

(2011) Stefan A.J. Timmer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Automatic generation of absolute myocardial blood flow images using [15O]H2O and a clinical PET/CT scanner

(2011) Hendrik J. Harms et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Microvascular Function Is Selectively Impaired in Patients With Hypertrophic Cardiomyopathy and Sarcomere Myofilament Gene Mutations

(2011) Iacopo Olivotto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evaluation of Techniques for the Quantification of Myocardial Scar of Differing Etiology Using Cardiac Magnetic Resonance

(2011) Andrew S. Flett et al.   JACC-Cardiovascular Imaging

Localization of the two tropomyosin-binding sites of troponin T

(2010) J.-P. Jin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Metabolic Modulator Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy

(2010) Khalid Abozguia et al.   CIRCULATION

Mapping Displacement and Deformation of the Heart With Local Sine-Wave Modeling

(2010) T. Arts et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING