Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis

(2019)   BMC Medicine

The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

(2019) Sha Joe Zhu et al.   eLife

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT

(2019) Jonathan Kim et al.   NATURE

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

(2019) Xue Li et al.   PLoS Genetics

Artemether–Lumefantrine and Dihydroartemisinin–Piperaquine Retain High Efficacy for Treatment of Uncomplicated Plasmodium falciparum Malaria in Myanmar

(2019) Kay Thwe Han et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Emergence and Spread of kelch13 Mutations Associated with Artemisinin Resistance in Plasmodium falciparum Parasites in 12 Thai Provinces from 2007 to 2016

(2018) Theerayot Kobasa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Do fitness costs explain the rapid spread of kelch13-C580Y substitutions conferring artemisinin resistance?

(2018) Shalini Nair et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study

(2018) Roberto Amato et al.   LANCET INFECTIOUS DISEASES

hmmIBD: software to infer pairwise identity by descent between haploid genotypes

(2018) Stephen F. Schaffner et al.   MALARIA JOURNAL

Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

(2018) Leila S. Ross et al.   Nature Communications

Predictors of antimalarial self-medication in illegal gold miners in French Guiana: a pathway towards artemisinin resistance

(2017) M Douine et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study

(2017) Mallika Imwong et al.   LANCET INFECTIOUS DISEASES

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar

(2017) Craig A. Bonnington et al.   MALARIA JOURNAL

Malaria epidemiology in low-endemicity areas of the northern coast of Ecuador: high prevalence of asymptomatic infections

(2017) Fabián E. Sáenz et al.   MALARIA JOURNAL

Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro

(2017) Judith Straimer et al.   mBio

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites

(2017) Hsiao-Han Chang et al.   PLoS Computational Biology

Indels, structural variation, and recombination drive genomic diversity inPlasmodium falciparum

(2016) Alistair Miles et al.   GENOME RESEARCH

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

(2016) Samuel O. Oyola et al.   MALARIA JOURNAL

Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir

(2016) Maylis Douine et al.   MALARIA JOURNAL

Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites

(2016) Timothy J.C. Anderson et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Worldwide Map ofPlasmodium falciparumK13-Propeller Polymorphisms

(2016) Didier Ménard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Continued Sensitivity ofPlasmodium falciparumto Artemisinin in Guyana, With Absence of Kelch Propeller Domain Mutant Alleles

(2016) Reyaud Rahman et al.   Open Forum Infectious Diseases

Independent Emergence of thePlasmodium falciparumKelch Propeller Domain Mutant Allele C580Y in Guyana

(2015) Stella M. Chenet et al.   JOURNAL OF INFECTIOUS DISEASES

Clonal population expansion in an outbreak of Plasmodium falciparum on the northwest coast of Ecuador

(2015) Fabián E. Sáenz et al.   MALARIA JOURNAL

COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data

(2015) Kevin Galinsky et al.   MALARIA JOURNAL

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

(2015) S. Bhatt et al.   NATURE

Genetic architecture of artemisinin-resistant Plasmodium falciparum

(2015) Olivo Miotto et al.   NATURE GENETICS

Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax

(2015) Eldin Talundzic et al.   PLoS One

Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation inpfcrt

(2015) Stéphane Pelleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

estMOI: estimating multiplicity of infection using parasite deep sequencing data

(2014) Samuel A. Assefa et al.   BIOINFORMATICS

Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

(2014) Shannon Takala-Harrison et al.   JOURNAL OF INFECTIOUS DISEASES

Were medicine quality and pharmaceutical management contributing factors in diminishing artemisinin efficacy in Guyana and Suriname?

(2014) Victor S Pribluda et al.   MALARIA JOURNAL

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

(2014) J. Straimer et al.   SCIENCE

Long term persistence of clonal malaria parasite Plasmodium falciparum lineages in the Colombian Pacific region

(2013) Diego F Echeverry et al.   BMC GENETICS

Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

(2013) Benoit Witkowski et al.   LANCET INFECTIOUS DISEASES

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

(2013) Olivo Miotto et al.   NATURE GENETICS

Discordant Temporal Evolution ofPfcrtandPfmdr1Genotypes and Plasmodium falciparum In Vitro Drug Susceptibility to 4-Aminoquinolines after Drug Policy Change in French Guiana

(2012) Eric Legrand et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Major Genome Region Underlying Artemisinin Resistance in Malaria

(2012) I. H. Cheeseman et al.   SCIENCE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Multiple independent introductions of Plasmodium falciparum in South America

(2011) E. Yalcindag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites

(2010) N. V. Dharia et al.   GENOME RESEARCH

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Origin and Evolution of Sulfadoxine Resistant Plasmodium falciparum

(2010) Sumiti Vinayak et al.   PLoS Pathogens

Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

(2009) Richard T. Eastman et al.   NATURE REVIEWS MICROBIOLOGY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE