Revisiting the Neuroblastoma Cell-Based Assay (CBA-N2a) for the Improved Detection of Marine Toxins Active on Voltage Gated Sodium Channels (VGSCs)

Presence of CTXs in moray eels and dusky groupers in the marine environment of the Canary Islands

(2020) Andres Sanchez-Henao et al.   AQUATIC TOXICOLOGY

Screening-level evaluation of marine benthic dinoflagellates toxicity using mammalian cell lines

(2020) Raquel A.F. Neves et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Evaluation of the new European Union reference method for paralytic shellfish toxins in shellfish: A review of twelve years regulatory monitoring using pre-column oxidation LC-FLD

(2019) Andrew D. Turner et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

An Attempt to Characterize the Ciguatoxin Profile in Seriola fasciata Causing Ciguatera Fish Poisoning in Macaronesia

(2019) Pablo Estevez et al.   Toxins

Predictive score and probability of CTX-like toxicity in fish samples from the official control of ciguatera in the Canary Islands

(2019) J. Andres Sanchez-Henao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Emerging Marine Biotoxins in Seafood from European Coasts: Incidence and Analytical Challenges

(2019) Pablo Estevez et al.   Foods

Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels

(2019) Keiichi Konoki et al.   Toxins

Ciguatoxin Occurrence in Food-Web Components of a Cuban Coral Reef Ecosystem: Risk-Assessment Implications

(2019) Lisbet Díaz-Asencio et al.   Toxins

Intraspecific Variability in the Toxin Production and Toxin Profiles of In Vitro Cultures of Gambierdiscus polynesiensis (Dinophyceae) from French Polynesia

(2019) Sébastien Longo et al.   Toxins

Ciguatoxin prevalence in 4 commercial fish species along an oceanic exposure gradient in the US Virgin Islands

(2018) Christopher R. Loeffler et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Application of solid phase adsorption toxin tracking (SPATT) devices for the field detection of Gambierdiscus toxins

(2018) Mélanie Roué et al.   HARMFUL ALGAE

Assessment of cytotoxicity in ten strains of Gambierdiscus australes from Macaronesian Islands by neuro-2a cell-based assays

(2018) Laia Reverté et al.   JOURNAL OF APPLIED PHYCOLOGY

A radioligand receptor binding assay for ciguatoxin monitoring in environmental samples: Method development and determination of quality control criteria

(2018) Lisbet Díaz-Asencio et al.   JOURNAL OF ENVIRONMENTAL RADIOACTIVITY

Toxicological Investigations on the Sea Urchin Tripneustes gratilla (Toxopneustidae, Echinoid) from Anaho Bay (Nuku Hiva, French Polynesia): Evidence for the Presence of Pacific Ciguatoxins

(2018) Hélène Taiana Darius et al.   Marine Drugs

Investigation of ciguatoxins in invasive lionfish from the greater caribbean region: Implications for fishery development

(2018) D. Ransom Hardison et al.   PLoS One

Solid Phase Adsorption Toxin Tracking (SPATT) Technology for the Monitoring of Aquatic Toxins: A Review

(2018) Mélanie Roué et al.   Toxins

Tissue Distribution and Elimination of Ciguatoxins in Tridacna maxima (Tridacnidae, Bivalvia) Fed Gambierdiscus polynesiensis

(2018) Mélanie Roué et al.   Toxins

Detection of pacific ciguatoxins using liquid chromatography coupled to either low or high resolution mass spectrometry (LC-MS/MS)

(2018) Manoella Sibat et al.   JOURNAL OF CHROMATOGRAPHY A

Development of an LC–MS/MS method to simultaneously monitor maitotoxins and selected ciguatoxins in algal cultures and P-CTX-1B in fish

(2018) J. Sam Murray et al.   HARMFUL ALGAE

A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis

(2018) Marcia Bodero et al.   Marine Drugs

New Insights into the Occurrence and Toxin Profile of Ciguatoxins in Selvagens Islands (Madeira, Portugal)

(2018) Pedro Costa et al.   Toxins

Implementation of liquid chromatography tandem mass spectrometry for the analysis of ciguatera fish poisoning in contaminated fish samples from Atlantic coasts

(2018) Pablo Estevez et al.   FOOD CHEMISTRY

Human neuronal cell based assay: A new in vitro model for toxicity evaluation of ciguatoxin

(2017) Teresa Coccini et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Screening for the presence of lipophilic marine biotoxins in shellfish samples using the neuro-2a bioassay

(2017) Marcia Bodero et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Toxicity screening of 13 Gambierdiscus strains using neuro-2a and erythrocyte lysis bioassays

(2017) Francesco Pisapia et al.   HARMFUL ALGAE

Taxonomic assignment of the benthic toxigenic dinoflagellate Gambierdiscus sp. type 6 as Gambierdiscus balechii (Dinophyceae), including its distribution and ciguatoxicity

(2017) Xinfeng Dai et al.   HARMFUL ALGAE

The prevalence of benthic dinoflagellates associated with ciguatera fish poisoning in the central Red Sea

(2017) Daniela Catania et al.   HARMFUL ALGAE

Biooxidation of Ciguatoxins Leads to Species-Specific Toxin Profiles

(2017) Tsuyoshi Ikehara et al.   Toxins

Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia)

(2017) Hélène Darius et al.   Toxins

Marine biotoxins and associated outbreaks following seafood consumption: Prevention and surveillance in the 21st century

(2017) Jonathan Nicolas et al.   Global Food Security-Agriculture Policy Economics and Environment

Analytical challenges to ciguatoxins

(2017) Toshiyuki Suzuki et al.   Current Opinion in Food Science

Analytical challenges for regulated marine toxins. Detection methods

(2017) Inés Rodríguez et al.   Current Opinion in Food Science

Ciguatoxicity of Gambierdiscus and Fukuyoa species from the Caribbean and Gulf of Mexico

(2017) R. Wayne Litaker et al.   PLoS One

Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean

(2017) Jorge Diogène et al.   Scientific Reports

Matrix effects on a cell-based assay used for the detection of paralytic shellfish toxins in bivalve shellfish samples

(2016) Ambbar Aballay-Gonzalez et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Evidence of the bioaccumulation of ciguatoxins in giant clams ( Tridacna maxima ) exposed to Gambierdiscus spp. cells

(2016) Mélanie Roué et al.   HARMFUL ALGAE

Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish

(2016) D. Ransom Hardison et al.   PLoS One

Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay

(2016) Richard J. Lewis et al.   PLoS One

Contribution to the risk characterization of ciguatoxins: LOAEL estimated from eight ciguatera fish poisoning events in Guadeloupe (French West Indies)

(2015) Virginie Hossen et al.   ENVIRONMENTAL RESEARCH

Exploration of new functional endpoints in neuro-2a cells for the detection of the marine biotoxins saxitoxin, palytoxin and tetrodotoxin

(2015) Jonathan Nicolas et al.   TOXICOLOGY IN VITRO

A saxitoxin-binding aptamer with higher affinity and inhibitory activity optimized by rational site-directed mutagenesis and truncation

(2015) X. Zheng et al.   TOXICON

Prevalence of ciguatoxins in lionfish (Pterois spp.) from Guadeloupe, Saint Martin, and Saint Barthélmy Islands (Caribbean)

(2015) Lucía Soliño et al.   TOXICON

Emergent Toxins in North Atlantic Temperate Waters: A Challenge for Monitoring Programs and Legislation

(2015) Marisa Silva et al.   Toxins

Dynamics of ciguatoxins from Gambierdiscus polynesiensis in the benthic herbivore Mugil cephalus: Trophic transfer implications

(2014) Aurélie Ledreux et al.   HARMFUL ALGAE

Distribution, abundance and diversity of Gambierdiscus spp. from a ciguatera-endemic area in Marakei, Republic of Kiribati

(2014) Yixiao Xu et al.   HARMFUL ALGAE

Determination of Toxins Involved in Ciguatera Fish Poisoning in the Pacific by LC/MS

(2014) Kentaro Yogi et al.   JOURNAL OF AOAC INTERNATIONAL

Bioanalytical chromatographic method validation according to current regulations, with a special focus on the non-well defined parameters limit of quantification, robustness and matrix effect

(2014) Oskar González et al.   JOURNAL OF CHROMATOGRAPHY A

A New Cytotoxicity Assay for Brevetoxins Using Fluorescence Microscopy

(2014) Jennifer McCall et al.   Marine Drugs

Detection of marine neurotoxins in food safety testing using a multielectrode array

(2014) Jonathan Nicolas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Involvement of both sodium influx and potassium efflux in ciguatoxin-induced nodal swelling of frog myelinated axons

(2014) César Mattei et al.   NEUROPHARMACOLOGY

The voltage-gated sodium channel: A major target of marine neurotoxins

(2014) César Mattei et al.   TOXICON

Simultaneous quantification of Pacific ciguatoxins in fish blood using liquid chromatography–tandem mass spectrometry

(2013) Yim Ling Mak et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pacific Ciguatoxins in Food Web Components of Coral Reef Systems in the Republic of Kiribati

(2013) Yim Ling Mak et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Invasive Lionfish (Pterois volitans): A Potential Human Health Threat for Ciguatera Fish Poisoning in Tropical Waters

(2013) Alison Robertson et al.   Marine Drugs

Marine neurotoxins: State of the art, bottlenecks, and perspectives for mode of action based methods of detection in seafood

(2013) Jonathan Nicolas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Bioavailability and intravenous toxicokinetic parameters for Pacific ciguatoxin P-CTX-1 in rats

(2013) Aurélie Ledreux et al.   TOXICON

MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets

(2012) Juan C. Stockert et al.   ACTA HISTOCHEMICA

Collaborative study for the detection of toxic compounds in shellfish extracts using cell-based assays. Part II: application to shellfish extracts spiked with lipophilic marine toxins

(2012) Aurélie Ledreux et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Collaborative study for the detection of toxic compounds in shellfish extracts using cell-based assays. Part I: screening strategy and pre-validation study with lipophilic marine toxins

(2012) Anne-Laure Sérandour et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Towards the standardisation of the neuroblastoma (neuro-2a) cell-based assay for ciguatoxin-like toxicity detection in fish: application to fish caught in the Canary Islands

(2012) A. Caillaud et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Evaluation of seafood toxicity in the Australes archipelago (French Polynesia) using the neuroblastoma cell-based assay

(2012) Ralph Pawlowiez et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Determination of Paralytic Shellfish Toxins in Shellfish by Receptor Binding Assay: Collaborative Study

(2012) Frances M. Van Dolah et al.   JOURNAL OF AOAC INTERNATIONAL

Linking ciguatera poisoning to spatial ecology of fish: A novel approach to examining the distribution of biotoxin levels in the great barracuda by combining non-lethal blood sampling and biotelemetry

(2012) Amanda C. O'Toole et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Validation of an accelerated solvent extraction liquid chromatography–tandem mass spectrometry method for Pacific ciguatoxin-1 in fish flesh and comparison with the mouse neuroblastoma assay

(2011) Jia Jun Wu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Detailed LC-MS/MS Analysis of Ciguatoxins Revealing Distinct Regional and Species Characteristics in Fish and Causative Alga from the Pacific

(2011) Kentaro Yogi et al.   ANALYTICAL CHEMISTRY

Spatial distribution of ciguateric fish in the Republic of Kiribati

(2011) Wing Hei Chan et al.   CHEMOSPHERE

Investigation of animal and algal bioassays for reliable saxitoxin ecotoxicity and cytotoxicity risk evaluation

(2011) François Perreault et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Identification of Ciguatoxins in Hawaiian Monk SealsMonachus schauinslandifrom the Northwestern and Main Hawaiian Islands

(2011) Marie-Yasmine Dechraoui Bottein et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Caribbean ciguatoxin profile in raw and cooked fish implicated in ciguatera

(2011) Ann Abraham et al.   FOOD CHEMISTRY

Proteomic analysis of hepatic tissue of ciguatoxin (CTX) contaminated coral reef fish Cephalopholis argus and moray eel Gymnothorax undulatus

(2011) Xi-Wen Jiang et al.   HARMFUL ALGAE

First Evidence of Palytoxin and 42-Hydroxy-palytoxin in the Marine Cyanobacterium Trichodesmium

(2011) Anne Sophie Kerbrat et al.   Marine Drugs

Toxicokinetics of the ciguatoxin P-CTX-1 in rats after intraperitoneal or oral administration

(2011) Marie-Yasmine Dechraoui Bottein et al.   TOXICOLOGY

An improved 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction assay for evaluating the viability of Escherichia coli cells

(2010) Hengwei Wang et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Update on Methodologies Available for Ciguatoxin Determination: Perspectives to Confront the Onset of Ciguatera Fish Poisoning in Europe

(2010) Amandine Caillaud et al.   Marine Drugs

Detection of ciguatoxin-like and paralysing toxins in Trichodesmium spp. from New Caledonia lagoon

(2010) Anne-Sophie Kerbrat et al.   MARINE POLLUTION BULLETIN

Colorimetric microbial viability assay based on reduction of water-soluble tetrazolium salts for antimicrobial susceptibility testing and screening of antimicrobial substances

(2009) Tadayuki Tsukatani et al.   ANALYTICAL BIOCHEMISTRY

Cell-based assay coupled with chromatographic fractioning: A strategy for marine toxins detection in natural samples

(2009) A. Caillaud et al.   TOXICOLOGY IN VITRO

Dual action of a dinoflagellate-derived precursor of Pacific ciguatoxins (P-CTX-4B) on voltage-dependent K+ and Na+ channels of single myelinated axons

(2009) Sébastien Schlumberger et al.   TOXICON

Toxic dinoflagellates (Dinophyceae) from Rarotonga, Cook Islands

(2009) Lesley L. Rhodes et al.   TOXICON

Ciguatera: the detection of neurotoxins in carnivorous reef fish from the coast of Cameroon, West Africa

(2008) P Bienfang et al.   AFRICAN JOURNAL OF MARINE SCIENCE

Detection of ciguatoxin in fish tissue using sandwich ELISA and neuroblastoma cell bioassay

(2008) Cara Empey Campora et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastoma×glioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins

(2008) Elisabeth Cañete et al.   TOXICON

Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins)

(2008) Aurélie Ledreux et al.   TOXICON

Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: Relationship to blood ciguatoxin concentrations

(2007) Marie-Yasmine Bottein Dechraoui et al.   TOXICOLOGY