Deconstructing cerebellar development cell by cell

Emerging connections between cerebellar development, behaviour and complex brain disorders

(2019) Aaron Sathyanesan et al.   NATURE REVIEWS NEUROSCIENCE

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation

(2019) Chia-Hsiang Chang et al.   DEVELOPMENTAL CELL

Childhood cerebellar tumours mirror conserved fetal transcriptional programs

(2019) Maria C. Vladoiu et al.   NATURE

Concepts and limitations for learning developmental trajectories from single cell genomics

(2019) Sophie Tritschler et al.   DEVELOPMENT

Organoid single-cell genomic atlas uncovers human-specific features of brain development

(2019) Sabina Kanton et al.   NATURE

On the nature and function of organizers

(2018) Alfonso Martinez Arias et al.   DEVELOPMENT

Using single‐cell genomics to understand developmental processes and cell fate decisions

(2018) Jonathan A Griffiths et al.   Molecular Systems Biology

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

(2018) Daniel E. Wagner et al.   SCIENCE

A Single-Cell Transcriptional Atlas of the Developing Murine Cerebellum

(2018) Robert A. Carter et al.   CURRENT BIOLOGY

The Use of Stem Cell-Derived Neurons for Understanding Development and Disease of the Cerebellum

(2018) Samuel P. Nayler et al.   Frontiers in Neuroscience

Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain

(2017) Blue B Lake et al.   NATURE BIOTECHNOLOGY

Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin+ progenitors

(2017) Alexandre Wojcinski et al.   NATURE NEUROSCIENCE

Photoreceptor Cilia and Retinal Ciliopathies

(2017) Kinga M. Bujakowska et al.   Cold Spring Harbor Perspectives in Biology

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

(2016) Atray Dixit et al.   CELL

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

(2016) Britt Adamson et al.   CELL

Consensus Paper: Cerebellar Development

(2015) Ketty Leto et al.   CEREBELLUM

Clonal analysis reveals granule cell behaviors and compartmentalization that determine the folded morphology of the cerebellum

(2015) E. Legue et al.   DEVELOPMENT

Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

(2015) Keiko Muguruma et al.   Cell Reports

Shh Signaling Protects Atoh1 from Degradation Mediated by the E3 Ubiquitin Ligase Huwe1 in Neural Precursors

(2014) Antoine Forget et al.   DEVELOPMENTAL CELL

Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects

(2014) Alexandros Onoufriadis et al.   HUMAN MOLECULAR GENETICS

Wls Provides a New Compartmental View of the Rhombic Lip in Mouse Cerebellar Development

(2014) J. Yeung et al.   JOURNAL OF NEUROSCIENCE

A High-Resolution Spatiotemporal Atlas of Gene Expression of the Developing Mouse Brain

(2014) Carol L. Thompson et al.   NEURON

Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum

(2014) Yusuke Seto et al.   Nature Communications

Peri- and Postnatal Development of Cerebellar Compartments in the Mouse

(2013) Izumi Sugihara et al.   CEREBELLUM

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences

(2013) M. Albert Basson et al.   Frontiers in Neuroanatomy

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome

(2013) Tian Yu et al.   eLife

Clustered Fine Compartmentalization of the Mouse Embryonic Cerebellar Cortex and Its Rearrangement into the Postnatal Striped Configuration

(2012) H. Fujita et al.   JOURNAL OF NEUROSCIENCE

Widespread Contribution of Gdf7 Lineage to Cerebellar Cell Types and Implications for Hedgehog-Driven Medulloblastoma Formation

(2012) Frances Y. Cheng et al.   PLoS One

Pattern formation during development of the embryonic cerebellum

(2012) F. V. Dastjerdi et al.   Frontiers in Neuroanatomy

Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary

(2011) N. A. Sunmonu et al.   DEVELOPMENT

Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome

(2011) Madeline A Lancaster et al.   NATURE MEDICINE

FGF17, a gene involved in cerebellar development, is downregulated in a patient with Dandy–Walker malformation carrying a de novo 8p deletion

(2011) Ginevra Zanni et al.   NEUROGENETICS

Preterm Delivery Disrupts the Developmental Program of the Cerebellum

(2011) Parthiv Haldipur et al.   PLoS One

Stochastic Mechanisms of Cell Fate Specification that Yield Random or Robust Outcomes

(2010) Robert J. Johnston et al.   Annual Review of Cell and Developmental Biology

GAP-43 is key to mitotic spindle control and centrosome-based polarization in neurons

(2010) Rashmi Mishra et al.   CELL CYCLE

Lack of Mid1, the Mouse Ortholog of the Opitz Syndrome Gene, Causes Abnormal Development of the Anterior Cerebellar Vermis

(2010) A. Lancioni et al.   JOURNAL OF NEUROSCIENCE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development

(2010) X. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem

(2010) V. V. Chizhikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Region-specific maturation of cerebral cortex in human fetal brain: diffusion tensor imaging and histology

(2009) Richa Trivedi et al.   NEURORADIOLOGY

Temporal control of neuronal diversity: common regulatory principles in insects and vertebrates?

(2008) J. Jacob et al.   DEVELOPMENT

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

(2008) E. Dessaud et al.   DEVELOPMENT

Comparative analysis of proneural gene expression in the embryonic cerebellum

(2008) Paola Zordan et al.   DEVELOPMENTAL DYNAMICS

Fast unfolding of communities in large networks

(2008) Vincent D Blondel et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

The evolution of cell types in animals: emerging principles from molecular studies

(2008) Detlev Arendt   NATURE REVIEWS GENETICS